Author/s: Shreya Narayanan, Christopher D. Jackson, MD
Diverticulitis involves inflammation of outpouchings of the intestinal wall, a condition known as diverticulosis.
Risk factors for diverticulosis include being older than 65 years, obesity (body mass index [BMI] of 30 or more), high blood pressure, type 2 diabetes, certain medications (...
Author/s: Elizabeth Alpert, Hugh Silk, Lisa Simon
Dental caries (tooth decay or cavities) refers to demineralization of teeth, which occurs after bacteria metabolize dietary carbohydrates into acid. More than 90% of US adults experience caries and 26% have untreated caries.
Author/s: Herbert Tilg, Salvatore Petta, Norbert Stefan, Giovanni Targher
Importance Metabolic dysfunction–associated steatotic liver disease (MASLD) includes a range of liver conditions, progressing from isolated steatosis (characterized by fat accumulation in the liver without inflammation) to metabolic dysfunction–associated steatohepatitis (MASH), which involves...
Author/s: Jedid-Jah Blom, Dominica Gidrewicz, Justine Turner, Donald R. Duerksen, M. Ines Pinto-Sánchez
Celiac disease is frequently undiagnosed, in part because of its highly variable clinical presentation.
Celiac disease can present with classic gastrointestinal symptoms (e.g., diarrhea, abdominal pain, bloating, weight loss), atypical or extraintestinal manifestations (e.g., anemia,...
Author/s: Shiyi Julia Zhu, Rana S. Hinman, Rachel K. Nelligan
Importance: Tai chi is a type of exercise recommended for knee osteoarthritis, but access to in-person tai chi can be limited.
Objective: To evaluate the effects of an unsupervised multimodal online tai chi intervention on knee pain and function for people with knee osteoarthritis.
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Author/s: Alison Flehr, Christopher Dowrick, Catherine Kaylor-Hughes, Jane Gunn
In this Viewpoint, we respond to the 2022 Lancet–World Psychiatric Association Commission’s call for united action on depression. We present primary care-focused recommendations synthesised from key outcomes of 16 observational cohorts of adults with depression in primary care, representing more...
Author/s: Jean H. Ashburn
Importance Hemorrhoidal disease, pathology of the tissue lining of the anal canal, affects approximately 10 million individuals in the US. Hemorrhoidal disease may impair quality of life due to bleeding, pain, anal irritation, and tissue prolapse.
Observations Hemorrhoids are classified...
Author/s: Bart J. van Essen, Daan C.H. Ceelen, Wouter Ouwerkerk, Tiew-Hwa K. Teng, Ganash N. Tharshana, Fook Ming Hew, Javed Butler, Faiez Zannad, Carolyn S. Lam, Justin Ezekowitz, Adriaan A. Voors, Jasper Tromp
Background: In 2022, a network meta-analysis showed that a combination of β-blockers, angiotensin receptor-neprilysin inhibitors (ARNi), mineralocorticoid receptor antagonists (MRAs), and sodium-glucose cotransporter 2 inhibitors (SGLT2i) was most effective in reducing all-cause mortality in...
Author/s: Alistair Mukondiwa, Callie L. Brown, Lindsay A. Thompson
This JAMA Pediatrics Patient Page describes respiratory syncytial virus (RSV) in children and how to prevent its spread.
Author/s: Kristine D. Olson, Daniella Meeker, Matt Troup
Importance: While in short supply and high demand, ambulatory care clinicians spend more time on administrative tasks and documentation in the electronic health record than on direct patient care, which has been associated with burnout, intention to leave, and reduced quality of care.
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