Secondary Prevention after Ischemic Stroke

Author/s: 
Karen L. Furie, Peter J. Kelly
Date Added: 
March 4, 2026
Journal/Publication: 
New England Journal of Medicine
Publication Date: 
February 18, 2026
Type: 
Meta-analyses, Reviews, and Guidelines
Format: 
Article
DOI (1): 
10.1056/NEJMcp2415601
PMID (1): 
41707139

RPR Commentary

A review of the causes of ischemic stroke and the risk reduction strategies available to prevent recurrences. James W. Mold, MD, MPH

Abstract

The risk of recurrent ischemic stroke can be reduced by managing modifiable risk factors and instituting a regimen of mechanism-specific secondary stroke prevention. Strategies for secondary prevention should be instituted as early as possible. Poststroke monitoring of risk metrics, lifestyle behaviors, and medication recommendations is of key importance.