Pertussis Infection in Adults

Author/s: 
Paul B. Cornia, Benjamin A. Lipsky
Date Added: 
February 26, 2026
Journal/Publication: 
JAMA
Publication Date: 
February 18, 2026
Type: 
Meta-analyses, Reviews, and Guidelines
Format: 
Article
DOI (1): 
10.1001/jama.2025.26153
PMID (1): 
41706481

RPR Commentary

A concise review of pertussis infection in adults. (Much more common than you might think.) James W. Mold, MD, MPH

Abstract

Pertussis, or whooping cough, is a highly contagious respiratory illness caused by Bordetella pertussis, a fastidious gram-negative coccobacillus that is a human pathogen without known animal or environmental reservoirs. There are 8 additional known Bordetella species, 3 of which can cause respiratory illness in humans: B parapertussis (which causes infection clinically indistinguishable from pertussis), B bronchiseptica, and B holmesii.