Importance: Approximately 27% of adults in the US and Canada report having ever used cannabis for medical purposes. An estimated 10.5% of the US population reports using cannabidiol (CBD), a chemical compound extracted from cannabis that does not have psychoactive effects, for therapeutic...
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Open Access Canadian guideline on HIV pre- and postexposure prophylaxis: 2025 update
Background: New HIV infections occur annually in Canada, highlighting the need for pre- and postexposure prophylaxis (PrEP and PEP). Through the Canadian Institutes of Health Research (CIHR) Pan-Canadian Network for HIV/AIDS and STBBI (sexually transmitted and blood-borne infections) Clinical...
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Lung Cancer in Nonsmoking Individuals: A Review
Importance: Lung cancer in nonsmoking individuals (defined as people who have smoked fewer than 100 cigarettes in their lifetime) accounts for 15% to 20% of all lung cancer cases worldwide. In the US, the annual incidence of lung cancer in nonsmoking individuals is 14.4 to 20.8 per 100 000...
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Addressing Faith-Based Concerns about Vaccination
Religious beliefs are cited as one cause of declining vaccination rates, and religious participation has been associated with hesitancy to receive vaccines. However, many personal vaccine objections attributed to faith-based reasons are more likely matters of personal faith interpretation rather...
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Continuous Glucose Monitoring
This JAMA Insights discusses continuous glucose monitoring use among individuals with type 2 diabetes, including types of devices, evidence of effectiveness, and adverse effects and contraindications.
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What Parents and Teens Need to Know About Testicular Pain
This JAMA Pediatrics Patient Page describes the symptoms and treatment for testicular torsion in boys.
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Approach to pelvic venous disorders
Objective: To provide a practical guide to help family physicians recognize, diagnose, and manage patients with pelvic venous disorders (PeVDs), often overlooked as causes of chronic pelvic pain and varicose veins.
Sources of information: This review is based on guidelines from the...
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Pharmacologic Treatment of Perinatal Depression
Approximately 1 in 7 individuals are affected by perinatal depression, defined as a depressive episode occurring during pregnancy or within 12 months after delivery. Although the diagnostic criteria are similar to those of major depressive disorder, perinatal depression may also include symptoms...
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Long QT Syndrome
To assess a physician’s expertise on the basis of whether the doctor checks a patient’s QT interval would be excessive, but the fact remains that in many cases, checking it saves lives. The author of a respected textbook on electrocardiography1 wrote, “The measurement of the QT interval has...
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Peripheral Neuropathy: A Review
Importance Peripheral neuropathy, defined as damage to peripheral nerves, affects approximately 1% of adults worldwide. More than 200 causes of peripheral neuropathy exist, with symptoms ranging in severity from mild toe numbness to debilitating symptoms that can require a wheelchair. Diabetes...
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