Background
Headaches resulting from proton pump inhibitor (PPI) use could cause discontinuation of PPI in as many as 40% of patients who experience such headaches. Previous studies focusing on acute headache risk from PPI use are rare and limited to clinical trials of a single PPI.
...Objectives
To estimate associations between long‐term use of proton pump inhibitors (PPIs) and pneumonia incidence in older adults in primary care.
Design
Longitudinal analyses of electronic medical records.
Setting
England
Participants
...
Context
Proton pump inhibitors (PPIs) are among the most commonly used drugs worldwide, and have been linked to acute interstitial nephritis. Less is known about the relationship between PPI use and chronic kidney disease (CKD).
Objective
To quantify the association between...
BACKGROUND
Actinic keratosis is the most frequent premalignant skin disease in the white population. In current guidelines, no clear recommendations are made about which treatment is preferred.
METHODS
We investigated the effectiveness of four frequently used field-directed...
BACKGROUND:
Type 2 diabetes is a chronic disorder that requires lifelong treatment. We aimed to assess whether intensive weight management within routine primary care would achieve remission of type 2 diabetes.
METHODS:
We did this open-label, cluster-randomised trial (...
What is the problem and what is known about it so far?
Many parents choose not to vaccinate their children because of worry about autism, even though the 1998 study claiming to show that children who receive the measles, mumps, rubella (MMR) vaccine were at increased risk...
OBJECTIVE:
To analyze injuries that were directly associated with yoga practice and identify specific poses that should be avoided in patients with osteopenia or osteoporosis.
PATIENTS AND METHODS:
We retrospectively reviewed the medical records of patients with injuries...
OBJECTIVE:
To investigate the efficacy of yoga as antihypertensive lifestyle therapy and identify moderators that account for variability in the blood pressure (BP) response to yoga.
METHODS:
We systematically searched 6 electronic databases from inception through June 4,...
The Library of the Royal College of Surgeons of England is home to a meticulously kept archive of the lives of medical students who attended Sir James Paget's anatomy lectures at St Bartholomew's Hospital in London, UK, between 1839 and 1859. Published in 1869, “What Becomes of Medical Students...
Poorly managed working practices, including poor provision of education to artificial stonecutters, has led to what has been called an epidemic of silicosis. Tony Kirby reports.
On Feb 21, 2019, Australia's national news network ABC reported the results of an audit of the stonecutting...
