An update for clinicians on the role of blood pressure for prevention of cardiiovascular events from the Healthy Hearts for OK project.
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Aspirin Use in Primary Care
An update for clinicians on the role of low-dose aspirin for prevention of cardiiovascular events from the Healthy Hearts for OK project.
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Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors
Porphyromonas gingivalis, the keystone pathogen in chronic periodontitis, was identified in the brain of Alzheimer’s disease patients. Toxic proteases from the bacterium called gingipains were also identified in the brain of Alzheimer’s patients, and levels correlated with tau and...
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CME-Approved Videos: Prevention of Stroke in Patients with Atrial Fibrillation
Videos from the Patient-Centered Outcomes Research Institute on the prevention of stroke in patients with atrial fibrillation.
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How Will Treating My Early-Stage Prostate Cancer Affect My Quality of Life?
Early-stage prostate cancer can be treated in different ways. The three main ways are active surveillance, surgery, and radiotherapy. Active surveillance means having your prostate checked every few months to make sure the cancer is not spreading. Surgery would take out the prostate, and...
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Antipsychotics for Children with Hyperactivity or Disruptive Disorders
New evidence can help clinicians, caretakers, and others weigh the benefits and harms of antipsychotic treatment for children and adolescents.
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Platelet-Rich Plasma Versus Hyaluronic Acid Injections for the Treatment of Knee Osteoarthritis: Results at 5 Years of a Double-Blind, Randomized Controlled Trial
BACKGROUND::
Platelet-rich plasma (PRP) injections have been proposed as a new conservative option for knee degeneration to provide symptomatic relief and delay surgical intervention. Although the current literature provides some evidence on the benefits of this technique compared with...
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Choosing Wisely - 5 Things Physicians & Patients Should Question
Don’t recommend daily home finger glucose testing in patients with Type 2 diabetes mellitus not using insulin.
Self-monitoring of blood glucose (SMBG) is an integral part of patient self-management in maintaining safe and target-driven glucose control in type 1 diabetes...
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Radical Prostatectomy or Watchful Waiting in Prostate Cancer - 29-Year Follow-up
BACKGROUND
Radical prostatectomy reduces mortality among men with clinically detected localized prostate cancer, but evidence from randomized trials with long-term follow-up is sparse.
METHODS
We randomly assigned 695 men with localized prostate cancer to watchful waiting or...
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Interpretation of Rapid Influenza Diagnostic Test (RIDT) Results
A number of factors can influence the results of RIDTs. The accuracy of RIDTs depends largely on the conditions under which they are used.
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