Aspirin is one of the most universally recognized and commonly prescribed medications worldwide. It is estimated that 48.7 million U.S. adults are taking aspirin for cardiovascular disease prevention; the majority (~73%) for primary prevention. The benefit of aspirin for secondary prevention of...
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Aspirin for the Primary Prevention of Cardiovascular Disease: Weighing Up the Evidence
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Exercise Videogames, Physical Activity, and Health: Wii Heart Fitness: A Randomized Clinical Trial
INTRODUCTION:
Adults who engage in regular physical activity have lower rates of morbidity and mortality than those who do not. Exercise videogames may offer an attractive, sustainable alternative or supplement to traditional modes of exercise. This study compared exercise videogames with...
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Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial
IMPORTANCE:
Catheter ablation is effective in restoring sinus rhythm in atrial fibrillation (AF), but its effects on long-term mortality and stroke risk are uncertain.
OBJECTIVE:
To determine whether catheter ablation is more effective than conventional medical therapy for...
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Effect of Catheter Ablation vs Medical Therapy on Quality of Life Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial
IMPORTANCE:
Catheter ablation is more effective than drug therapy in restoring sinus rhythm in patients with atrial fibrillation (AF), but its incremental effect on long-term quality of life (QOL) is uncertain.
OBJECTIVE:
To determine whether catheter ablation is more...
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Reducing Risk for Patients on Long-Term Opioids
Safer prescribing of opioids: algorithm for managing patients already receiving long-term opioids.
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Pain and Opioid Management in Primary Care
Oklahoma ranked 5th nationally in rates of opioid prescribing in 2016, with 97.9 opioid prescriptions per 100 people. Opioids account for the majority of prescription drug-related overdose deaths. Despite recent declines, deaths from opioids remain common.
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Pulmonary Health Effects of Agriculture
PURPOSE OF REVIEW:
Occupational exposures in the agricultural industry are associated with numerous lung diseases, including chronic obstructive pulmonary disease, asthma, hypersensitivity pneumonitis, lung cancer, and interstitial lung diseases. Efforts are ongoing to ascertain...
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Pharmacotherapy for social anxiety disorder (SAnD)
Background
Recognition is growing that social anxiety disorder (SAnD) is a chronic and disabling disorder, and data from early trials demonstrate that medication may be effective in its treatment. This systematic review is an update of an earlier review of pharmacotherapy of SAnD.
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Improving the Adoption of Advance Directives in Primary Care Practices
Background: Oklahoma's Advance Directive completion rate is less than 10%. We compared the implementation performance of 2 advance directive forms to determine which form could be more successfully disseminated.
Methods: The implementation of the Oklahoma Advance...
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Prescribing Statins to Reduce Cardiovascular Disease – Ten Common Misconceptions
Statins (HMG-CoA reductase inhibitors) are one of the most widely prescribed medications in the world. However, their use in patients is often inappropriate because these medications have some unique properties not shared with other pharmaceuticals. This Commentary lists ten common...
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