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Incidence and Estimated Vaccine Effectiveness Against Hospitalizations for All-Cause Pneumonia Among Older US Adults Who Were Vaccinated and Not Vaccinated With 13-Valent Pneumococcal Conjugate Vaccine

Author/s: Hsiao, A., Hansen, J., Timbol, J., Lewis, N., Isturiz, R., Alexander-Parrish, R., McLaughlin, J., Gessner, B. D., Klein, N. P.

Importance: Following routine use of 13-valent pneumococcal conjugate vaccine (PCV13) in children in 2010, invasive pneumococcal disease rates have decreased substantially in children and adults. In 2014, the Advisory Committee for Immunization Practices recommended routine use of PCV13 among...

Keywords/Tags:
Vaccine Effectiveness All-Cause Pneumonia 13-Valent Pneumococcal Conjugate Vaccine PCV13

Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment: A Systematic Review and Meta-analysis

Author/s: Byrne, P., Demasi, M., Jones, M., Smith, S. M., O'Brien, K. K., DuBroff, R.

Importance: The association between statin-induced reduction in low-density lipoprotein cholesterol (LDL-C) levels and the absolute risk reduction of individual, rather than composite, outcomes, such as all-cause mortality, myocardial infarction, or stroke, is unclear.

Objective: To...

Keywords/Tags:
"Cholesterol Statin Treatment meta-analysis Systemic Review

Diagnosis and management of postural orthostatic tachycardia syndrome

Author/s: Raj, S. R., Fedorowski, A., Sheldon, R. S.

Postural orthostatic tachycardia syndrome (POTS) is a chronic multisystem disorder; the cardinal feature is orthostatic tachycardia.

Patients with POTS have symptoms of orthostatic intolerance that improve with recumbence.

Girls and women are more commonly affected with POTS,...

Keywords/Tags:
POTS diagnosis management Postural Orthostatic Tachycardia Syndrome

Acute Cholecystitis A Review

Author/s: Gallaher, J. R., Charles, A.

Importance Gallbladder disease affects approximately 20 million people in the US. Acute cholecystitis is diagnosed in approximately 200 000 people in the US each year.

Observations Gallstone-associated cystic duct obstruction is responsible for 90% to 95% of the cases of acute...

Keywords/Tags:
Cholecystitis Gallbladder disease acalculous cholecystitis Critical Illness

Evaluation of Budesonide-Formoterol for Maintenance and Reliever Therapy Among Patients With Poorly Controlled Asthma A Systematic Review and Meta-analysis

Author/s: Beasley, R., Harrison, T., Peterson, S., Gustafson, P., Hamblin, A., Bengtsson, T., Fageras, M.

Importance: The Global Initiative for Asthma (GINA) recommends 2 alternative treatments for patients receiving treatment at steps 3 to 5: single inhaler combination inhaled corticosteroid-formoterol as both maintenance and reliever (SMART) or inhaled corticosteroid-long-acting β2-agonist as...

Keywords/Tags:
Budesonide-Formoterol therapy asthma Inhaler

Diagnosis of Lyme Disease

Author/s: Pitrak, D, Nguyen, C. T., Cifu, A. S.

Lyme disease is the most common tick-borne illness in the US, occurring predominantly in the Northeast, the upper Midwest, and Northern California, with increasing incidence and geographic range.1 Lyme disease can cause a skin lesion at the site of the initial tick bite as well as disseminated...

Keywords/Tags:
Lyme disease diagnosis US tick-borne illness

GLP1Agonists and SGLT2 Inhibitors Table

Author/s: Mold, J. W.

Based upon the following two meta-analyses:
1. Alexander JT, et al. The longer-term benefits and harms of glucagon-like peptide-1 receptor agonists: A Systematic review and meta-analysis. JGIM, 2021; 7(2): 415-43.
2. Alexander JT, et al. Longer-term benefits and risks of sodium-...

Child & Adolescent Immunization Schedule

Author/s: Centers for Disease Control and Prevention

Recommendations for Ages 18 Years or Younger, United States, 2022
Keywords/Tags:
child adolescent Immunization Immunization Schedule

Dietary recommendations for prevention of atherosclerosis

This review aims at summarizing updated evidence on cardiovascular disease (CVD) risk associated with consumption of specific food items to substantiate dietary strategies for atherosclerosis prevention. A systematic search on PubMed was performed to identify meta-analyses of cohort studies and...

Keywords/Tags:
Atherosclerosis Coronary Heart Disease cardiovascular disease diet

Lateral epicondylosis

Author/s: Li, Y., Liu, F., Badre, A.

Lateral epicondylosis tennis elbow is a degenerative noninflammatory condition of the common extensor origin at the lateral epicondyle of the elbow Tennis elbow has a prevalence of 1 3 peaking at age 35 50 years 1 It is associated with smoking and with a combination of repetitive and forceful...

Keywords/Tags:
Tennis Elbow Elbow Condition Common Extensor Origin smoking

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