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Therapy for Mild to Moderate Asthma

Author/s: Gray, S. E., Cife, A. S., Press, V. G.

GUIDELINE TITLE Global Strategy for Asthma Management
and Prevention (GINA Strategy Report)
RELEASE DATE April 26, 2021
PRIOR VERSION April 3, 2020
DEVELOPER AND FUNDING SOURCE The Global Initiative for
Asthma (GINA)
TARGET POPULATION Patients aged 12 y with...

Keywords/Tags:
asthma Mild to Moderate Asthma therapy recommendations Asthma Therapy

Effect of Physical Therapy vs Arthroscopic Partial Meniscectomy in People With Degenerative Meniscal Tears: Five-Year Follow-up of the ESCAPE Randomized Clinical Trial

Author/s: Noorduyn, J. C. A., Van de Graaf, V. A., Willigenburg, N. W., Scholten-Peeters, G. G. M., Kret, Kret, E. J., Van Dijk, R. A., Buchbinder, R., Hawker, G. A., Coppieters, M. W., Poolman, R. W., ESCAPE Research Group

Importance: There is a paucity of high-quality evidence about the long-term effects (ie, 3-5 years and beyond) of arthroscopic partial meniscectomy vs exercise-based physical therapy for patients with degenerative meniscal tears.

Objectives: To compare the 5-year effectiveness of...

Keywords/Tags:
Knee Injuries Follow-Up Studies randomized controlled trial Meniscus Injuries Meniscectomy

Women’s health update: A literature review impacting primary care

Author/s: Dolan, B. M., Merriam, S., Prifti, C. A., Walsh, J. M.

The authors review studies on key issues in women’s health with potential impact on internal medicine practice. The reviewed articles discuss cardiovascular disease risks, bone health, breast cancer genetics, cervical cancer prevention, depression in the peripartum period, pelvic pain, and...

Keywords/Tags:
Women's Health primary care Literature Review Internal Medicine Practice Disease Risks

Gabapentin Increasingly Implicated in Overdose Deaths

Author/s: Kuehn, B. M.

Gabapentin Increasingly Implicated
in Overdose Deaths
Postmortem toxicology tests detected gabapentin in almost 1 in 10 US overdose deaths
between 2019 and 2020.In about half of the
cases, a medical examiner or coroner ruled
the drug was a cause of the death,...

Keywords/Tags:
gabapentin Insurance Benefits Off-Label Use Drug Overdose

Effect of Physical Therapy vs Arthroscopic Partial Meniscectomy in People With Degenerative Meniscal Tears: Five-Year Follow-up of the ESCAPE Randomized Clinical Trial

Author/s: Noordyun, J. C. A., Van de Graaf, V. A., Willigenburg, N. W., Scholten-Peeters, G. G. M., Kret, E. J., Van Dijk, R. A., Buchbinder, R., Hawker, G. A., Coppieters, M. W., Poolman, R. W., ESCAPE Research Group

Importance: There is a paucity of high-quality evidence about the long-term effects (ie, 3-5 years and beyond) of arthroscopic partial meniscectomy vs exercise-based physical therapy for patients with degenerative meniscal tears.

Objectives: To compare the 5-year effectiveness of...

Keywords/Tags:
physical therapy Arthroscopic Partial Meniscectomy clinical trial Knee osteoarthritis Degenerative Meniscal Tear

Effect of Varenicline Added to Counseling on Smoking Cessation Among African American Daily Smokers The Kick It at Swope IV Randomized Clinical Trial

Author/s: Cox, L. S., Nollen, N. L., Mayo, M. S., Faseru, B., Greiner, A., Ellerbeck, E. F., Krebill, R., Tyndale, R. F., Benowitz, N. L., Ahluwalia, J. S.

Importance: African American smokers have among the highest rates of tobacco-attributable morbidity and mortality in the US, and effective treatment is needed for all smoking levels.

Objectives: To evaluate the efficacy of varenicline vs placebo among African American adults who are light...

Keywords/Tags:
Varenicline smoking African Americans Smokers clinical trial

Long-Acting Reversible Contraception With Contraceptive Implants and Intrauterine Devices

Author/s: Averbach, S., Hofler, L.

Long-acting reversible contraception (LARC), including contraceptive implants and intrauterine devices (IUDs), is highly effective, with typical-use failure rates of less than 1 pregnancy per 100 person-years of use.1 Fertility returns rapidly after discontinuation of LARC.
Keywords/Tags:
contraception Contraceptive Implants Intrauterine Devices

Chronic anal pain: A review of causes, diagnosis, and treatment

Author/s: Knowles, C. H., Cohen, R. C.

Chronic anal pain is diffi cult to diagnose and treat, especially with no obvious anorectal cause apparent on clinical examination. This review identifi es 3 main diagnostic
categories for chronic anal pain: local causes, functional
anorectal pain, and neuropathic pain syndromes....

Keywords/Tags:
Anal Pain Causes diagnosis treatment chronic pain

Cannabis-Based Products for Chronic Pain : A Systematic Review

Author/s: McDonah, M. S., Morasco, B. J., Wagner, J., Ahmed, A. Y., Fu, R., Kansagara, D., Chou, R.

Background: Contemporary data are needed about the utility of cannabinoids in chronic pain.

Purpose: To evaluate the benefits and harms of cannabinoids for chronic pain.

Data sources: Ovid MEDLINE, PsycINFO, EMBASE, the Cochrane Library, and Scopus to January 2022.

Study...

Keywords/Tags:
Adverse events cannabinoids cannabis neuropathic pain Systematic reviews

The monkeypox virus

Author/s: Halani, S., Mishra, S., Bogoch, I. I.

Monkeypox is a viral infection with person-to-person
transmission through direct contact or fomites
The virus is endemic to West and Central Africa.1
Animal-to-human transmission may initiate outbreaks, and person-to-person transmission
occurs through direct, close...

Keywords/Tags:
Monkeypox Virus Transmission Precautions 'Vaccination

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