Author/s:     Jane R. Montealegre, Susan G. Hilsenbeck, Shaun Bulsara  
  
          Importance  There are limited data on the effectiveness of mailed self-collection to increase cervical cancer screening (CCS) participation in underresourced health care settings.
Objective  To compare the effectiveness of mailed self-collection kits, with and without patient navigation,...
     
     
  
      
    
      Author/s:     Jane R. Montealegre, Susan G. Hilsenbeck, Shaun Bulsara  
  
          Importance  There are limited data on the effectiveness of mailed self-collection to increase cervical cancer screening (CCS) participation in underresourced health care settings.
Objective  To compare the effectiveness of mailed self-collection kits, with and without patient navigation,...
     
     
  
      
    
      Author/s:     Jeffry Florian, Pablo Salcedo, Keith Burkhart, Aanchal Shah, Lakshmi Manasa S Chekka, Dro Keshishi, Vikram Patel, ShanChao Yang, Melanie Fein, Ryan DePalma, Murali Matta, David G Strauss, Rodney Rouse  
  
          Importance  The wide use of unregulated cannabidiol (CBD) products among consumers raises safety concerns. Most research on CBD has studied the relatively high doses used by patients taking prescription CBD. However, limited safety data are available at lower doses.
Objective  To study...
     
     
  
      
    
      Author/s:     Shalender Bhasin, Peter J Snyder  
  
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In clinical trials involving middle-aged and older men with hypogonadism, testosterone treatment led to improved sexual activity and libido, correction of anemia, and modestly improved energy, mood, and walking ability. (The following key points also refer to findings from clinical...
     
     
  
      
    
      Author/s:     Daehoon Kim, MD, Jaemin Shim, MD, Eue-Keun Choi, MD  
  
          Importance: Data from randomized clinical trials on a long-term anticoagulation strategy for patients after catheter-based ablation for atrial fibrillation (AF) are lacking.
Objective: To evaluate whether discontinuing oral anticoagulant therapy provides superior clinical outcomes...
     
     
  
      
    
      Author/s:     Gilles Lemesle, M.D., Ph.D., Romain Didier, M.D., Ph.D., Philippe Gabriel Steg, M.D., Tabassome Simon, M.D., Ph.D., Gilles Montalescot, M.D., Ph.D., Nicolas Danchin, M.D., Christophe Bauters, M.D., Ph.D.  
  
          Background: The appropriate antithrombotic regimen for patients with chronic coronary syndrome who are at high atherothrombotic risk and receiving long-term oral anticoagulation remains unknown.
Methods: We conducted a multicenter, double-blind, randomized, placebo-controlled trial in...
     
     
  
      
    
      Author/s:     Sofie Mesens, Andrew D Krystal, Rama Melkote, Haiyan Xu, Gahan Pandina, Jay B Saoud, Remy Luthringer, Adam Savitz, Wayne C Drevets  
  
          Importance: Existing pharmacological treatments for insomnia have significant limitations.
Objective: To assess the effective dose range, safety, and tolerability of the novel selective orexin-2 receptor antagonist seltorexant in insomnia disorder.
Design, setting, and participants...
     
     
  
      
    
      Author/s:     Kevin Lieu, MD, Kathy T. LeSaint, MD, Zhanna Livshits, MD  
  
          This JAMA Patient Page describes the venomous snakes found in the US as well as snakebite symptoms, treatment, and prevention.
     
     
  
      
    
      Author/s:     Mathur A, Bhat A, Gohar A  
  
          Restless Legs Syndrome (RLS) or Willis‑Ekbom Disease is a sensorimotor condition marked by an irresistible need to move the legs, typically accompanied by uncomfortable sensations that peak during periods of rest and disrupt nightly sleep. Early identification in primary care is essential, as...
     
     
  
      
    
      Author/s:     Anand Vaidya, James Findling, Irina Bancos  
  
          Importance: Adrenal insufficiency is a syndrome of cortisol deficiency and is categorized as primary, secondary, or glucocorticoid induced. Although primary and secondary adrenal insufficiency are rare, affecting less than 279 per 1 million individuals, glucocorticoid-induced adrenal...