Description: Antimicrobial overuse is a major health care issue that contributes to antibiotic resistance. Such overuse includes unnecessarily long durations of antibiotic therapy in patients with common bacterial infections, such as acute bronchitis with chronic obstructive...
Recent Resources
Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians
Safety and tolerability of natural and synthetic cannabinoids in adults aged over 50 years: A systematic review and meta-analysis
Background: Cannabinoid-based medicines (CBMs) are being used widely in the elderly. However, their safety and tolerability in older adults remains unclear. We aimed to conduct a systematic review and meta-analysis of safety and tolerability of CBMs in adults of age ≥50 years....
Management of Persistent Pain in the Older Patient A Clinical Review
Importance: Persistent pain is highly prevalent, costly, and frequently disabling in later life.
Objective: To describe barriers to the management of persistent pain among older adults, summarize current management approaches, including pharmacologic and...
Screening for Lung Cancer US Preventive Services Task Force Recommendation Statement
Importance: Lung cancer is the second most common cancer and the leading cause of cancer death in the US. In 2020, an estimated 228 820 persons were diagnosed with lung cancer, and 135 720 persons died of the disease. The most important risk factor for lung cancer is smoking....
Responding to Unsafe Opioid Use: Abandon the Drug, Not the Patient
Physicians have a legal and ethical duty to protect their patients and support them during times of clinical need; the decision to end a doctor-patient relationship should not be made lightly. However, in a recent survey of 794 primary care practices, 90% reported discharging patients in the...
Once-Weekly Semaglutide in Adults with Overweight or Obesity
Background: Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle intervention has not been confirmed.
Methods: ...
Quick Guide to Primary Care First
Primary Care First is a voluntary five-year payment model that rewards value and quality by offering an innovative payment structure to support advanced primary care delivery. Primary Care First aims to improve quality and access to care for all patients, particularly those with complex chronic...
Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke: A Review
Importance: Stroke is the fifth leading cause of death and a leading cause of disability in the United States, affecting nearly 800 000 individuals annually.
Observations: Sudden neurologic dysfunction caused by focal brain ischemia with imaging evidence...
Mobile phone text messaging and app-based interventions for smoking cessation
Background: Mobile phone-based smoking cessation support (mCessation) offers the opportunity to provide behavioural support to those who cannot or do not want face-to-face support. In addition, mCessation can be automated and therefore provided affordably even in resource-poor...
Mild bleeding disorders in adults
About 11% of patients in primary care reported bleeding symptoms in a 2010 Canadian study.1 Mild bleeding disorders should be considered in patients with disproportionate bleeding (i.e., excessive postsurgical bleeding...