This is a summary of a systematic review evaluating the evidence regarding the comparative accuracy (the balance of sensitivity and specificity) and possible adverse consequences (both direct and indirect) of various methods used to diagnose celiac disease. The systematic review included 60...
Recent Resources
Diagnosis, Prevention, and Treatment of C. difficile: Current State of the Evidence
Focus
This is a summary of a systematic review that evaluated the recent evidence regarding the accuracy of diagnostic tests and the effectiveness of interventions for preventing and treating...
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Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women
Background
Pelvic floor muscle training (PFMT) is the most commonly used physical therapy treatment for women with stress urinary incontinence (SUI). It is sometimes also recommended for mixed urinary incontinence (MUI) and, less commonly, urgency urinary incontinence (UUI).
This...
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Nonsurgical Treatments for Urinary Incontinence in Women: A Systematic Review Update
Introduction. About 17 percent of adult women have had urinary incontinence (UI), classified as stress, urgency, or mixed. Stress UI is associated with an inability to retain urine with activities that increase intraabdominal pressure. Urgency UI is associated with the sudden,...
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Association Between Use of Sodium-Glucose Cotransporter 2 Inhibitors, Glucagon-like Peptide 1 Agonists, and Dipeptidyl Peptidase 4 Inhibitors With All-Cause Mortality in Patients With Type 2 Diabetes
IMPORTANCE:
The comparative clinical efficacy of sodium-glucose cotransporter 2 (SGLT-2) inhibitors, glucagon-like peptide 1 (GLP-1) agonists, and dipeptidyl peptidase 4 (DPP-4) inhibitors for treatment of type 2 diabetes is unknown.
OBJECTIVE:
To compare the efficacies of...
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2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task F
Preamble
Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health. In 2013, the National Heart, Lung...
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Oral Care Measures for Preventing Nursing Home-Acquired Pneumonia
BACKGROUND:
Pneumonia occurring in residents of long-term care facilities and nursing homes can be termed 'nursing home-acquired pneumonia' (NHAP). NHAP is the leading cause of mortality among residents. NHAP may be caused by aspiration of oropharyngeal flora into the lung, and by failure...
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How to Excel at Access — and Why It Matters
Health care spending in the United States totaled $3.3 trillion in 2016, more than double the amount spent in 2000. Twenty percent of the cost went toward physician services, with primary care accounting for approximately 7 percent.
These rising costs have real consequences for patients....
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Buprenorphine to Treat Opioid Use Disorder: A Practical Guide
Opioids were involved in 42,249 deaths in the United States in 2016, and opioid overdoses have quintupled since 1999.1 Among the causes behind these statistics is increased opiate prescribing by physicians—with primary care providers accounting for about one half of opiate prescriptions.2 As a...
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Management of Systolic BP in the Elderly
Discuss management of blood pressure in the elderly:
§ Disease or risk factor
§ BP components and their significance
§ Benefits and hazards of BP reduction
§ Other ways to reduce CV risk and law of diminishing returns
§ BP...
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