On December 11, 2020, the US Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for the Pfizer-BioNTech coronavirus disease 2019 (COVID-19) vaccine, administered as 2 doses separated by 21 days....
Recent Resources
Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Pfizer-BioNTech COVID-19 Vaccine
A Battery of Easily Accessible, Simple Tools for the Assessment of Concussion in Children
Objective: To determine whether a non-proprietary, novel testing battery can identify recently concussed children within 8 weeks of injury.
Study design: In total, 568 clinic outpatients aged 10-18 years were sorted into 3 groups: 316 had never been...
Development and Assessment of a Pictographic Pediatric Constipation Action Plan
Objective: To assess the Uniformed Services Constipation Action Plan (USCAP) as an evidence-based, personalized, clinical action tool with pictograms to aid clinicians and families in the management of functional constipation.
Study design: The USCAP...
Discriminating Multisystem Inflammatory Syndrome in Children Requiring Treatment from Common Febrile Conditions in Outpatient Settings
Objectives: To examine whether patients with multisystem inflammatory syndrome in children (MIS-C) demonstrated well-defined clinical features distinct from other febrile outpatients, given the difficulties of seeing acute care visits during the severe acute respiratory syndrome...
Bupropion and Naltrexone in Methamphetamine Use Disorder
BACKGROUND
The use of naltrexone plus bupropion to treat methamphetamine use disorder has not been well studied.
METHODS
We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the use of a sequential parallel comparison design to evaluate the...
Clinical diagnosis of benign paroxysmal positional vertigo and vestibular neuritis
Not available
Bupropion and Naltrexone in Methamphetamine Use Disorder
BACKGROUND
The use of naltrexone plus bupropion to treat methamphetamine use disorder has not been well studied.
METHODS
We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the use of a sequential parallel comparison design to evaluate the...
Stepped Exercise Program for Patients With Knee Osteoarthritis: A Randomized Controlled Trial
Background: Physical therapy (PT) and other exercise-based interventions are core components of care for knee osteoarthritis (OA), but both are underutilized, and some patients have limited access to PT services. This clinical trial is examining a STepped Exercise Program for...
Weekly and Monthly Subcutaneous Buprenorphine Depot Formulations vs Daily Sublingual Buprenorphine With Naloxone for Treatment of Opioid Use Disorder: A Randomized Clinical Trial
Importance: Buprenorphine treatment for opioid use disorder may be improved by sustained-release formulations.
Objective: To determine whether treatment involving novel weekly and monthly subcutaneous (SC) buprenorphine depot formulations is noninferior...
Dynamics and Correlation Among Viral Positivity, Seroconversion, and Disease Severity in COVID-19
Background: The understanding of viral positivity and seroconversion during the course of coronavirus disease 2019 (COVID-19) is limited.
Objective: To describe patterns of viral polymerase chain reaction (PCR) positivity and evaluate their correlations...