This JAMA Patient Page describes the types of canker sores and how they can be treated.
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What Teens Should Know About Choosing Contraception
This JAMA Pediatrics Patient Page describes what teens should consider when choosing contraception methods.
Chronic urticaria: unmet needs, emerging drugs, and new perspectives on personalised treatment
Chronic urticaria is a common and debilitating mast cell-driven skin disease presenting with itchy wheals, angio-oedema, or both. Chronic urticaria is classified as spontaneous (without definite triggers) and inducible (with definite and subtype-specific triggers; eg, cold or pressure). Current...
Heat-Related Illness in Athletes
This JAMA Insights discusses heat-related illness in athletes, including risk factors, prevention, symptoms, and management.
Medications for Obesity: A Review
Importance: Obesity affects approximately 19% of women and 14% of men worldwide and is associated with increased morbidity. Antiobesity medications (AOMs) modify biological processes that affect appetite and significantly improve outcomes, such as type 2 diabetes, hypertension, and dyslipidemia...
Interventions for High Body Mass Index in Children and Adolescents: US Preventive Services Task Force Recommendation Statement
Importance: Approximately 19.7% of children and adolescents aged 2 to 19 years in the US have a body mass index (BMI) at or above the 95th percentile for age and sex, based on Centers for Disease Control and Prevention growth charts from 2000. The prevalence of high BMI increases with age and is...
Acute Abdomen in the Modern Era
Acute abdominal pain is one of the most common symptoms in patients presenting to the emergency department and accounts for 5 to 10% of all emergency department visits. Pathophysiological conditions that lead to surgical interventions in such patients are mainly gastrointestinal obstruction,...
What Parents Need to Know About Peanut Allergy
Peanut allergy can range from mild to severe, even causing life-threatening reactions.
Peanut allergy affects 1% to 3% of people in the US. It typically develops in young children and usually lasts their whole life. While there is no definitive cure once someone has a peanut allergy at...
Dupilumab for COPD with Blood Eosinophil Evidence of Type 2 Inflammation
Background: Dupilumab, a fully human monoclonal antibody that blocks the shared receptor component for interleukin-4 and interleukin-13, key and central drivers of type 2 inflammation, has shown efficacy and safety in a phase 3 trial involving patients with chronic obstructive pulmonary disease...
Ketamine vs Electroconvulsive Therapy for Treatment-Resistant Depression: A Secondary Analysis of a Randomized Clinical Trial
Importance: The ELEKT-D: Electroconvulsive Therapy (ECT) vs Ketamine in Patients With Treatment Resistant Depression (TRD) (ELEKT-D) trial demonstrated noninferiority of intravenous ketamine vs ECT for nonpsychotic TRD. Clinical features that can guide selection of ketamine vs ECT may inform...