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A retrospective cohort study of 12,306 pediatric COVID‑19 patients in the United States

Author/s: Parcha, V., Booker, K.S., Kalra, R., Kuranz, S., Berra, L., Arora, G., Arora, P.

Children and adolescents account for ~ 13% of total COVID-19 cases in the United States. However, little is known about the nature of the illness in children. The reopening of schools underlines the importance of understanding the epidemiology of pediatric COVID-19 infections. We sought to...

Keywords/Tags:
COVID-19 pediatrics United States children 2019 novel coronavirus coronavirus

Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma: A Systematic Review and Meta-analysis

Author/s: Kim, L.H.Y., Saleh, C., Whalen-Browne, A., O'Byrne, P.M., Chu, D.K.

Importance: The benefits and harms of adding long-acting muscarinic antagonists (LAMAs) to inhaled corticosteroids (ICS) and long-acting β2-agonists (LABAs) for moderate to severe asthma remain unclear.

Objective: To systematically synthesize the outcomes...

Keywords/Tags:
asthma inhalers Inhaler Therapy

Screening for Colorectal Cancer US Preventive Services Task Force Recommendation Statement

Author/s: Davidson, K. W., Barry, M. J., Mangione, C. M., Cabana, M., Caughey, A. B., Davis, E. M., Donahue, K. E., Doubeni, C. A., Krist, A. H., Kubik, M., Li, L., Ogedegbe, G., Owens, D. K., Pbert, L., Silverstein, M., Stevermer, J., Tseng, C., Wong, J. B.

Abstract

Importance: Colorectal cancer is the third leading cause of cancer death for both men and women, with an estimated 52 980 persons in the US projected to die of colorectal cancer in 2021. Colorectal cancer is most frequently diagnosed among persons aged 65 to 74...

Keywords/Tags:
cancer colorectal men women screening

Update to U.S. Selected Practice Recommendations for Contraceptive Use: Self-Administration of Subcutaneous Depot Medroxyprogesterone Acetate

Author/s: Curtis, K. M., Nguyen, A., Reeves, J. A., Clark, E. A., Folger, S. G., Whiteman, M. K.

U.S. Selected Practice Recommendations for Contraceptive Use (U.S. SPR), adapted by CDC from global guidance developed by the World Health Organization (WHO), provides evidence-based guidance on contraceptive use for U.S. health care providers (1). During January-February, 2021, CDC evaluated...

Keywords/Tags:
contraceptive self-administration contraception decision making

Final Report of a Trial of Intensive versus Standard Blood-Pressure Control

Author/s: Lewis, C. E., Fine, L. J., Beddhu, S., Cheung, A. K., Cushman, W. C., Cutler, J. A., Evans, G. W., Johnson, K. C., Kitzman, D. W., Oparil, S., Rahman, M., Reboussin, D. M., Rocco, M. V., Sink, K, M., Snyder, J. K., Whelton, P. K., Williamson, J. D., Wright Jr., J. T., Ambrosius, W. T.

Background: In a previously reported randomized trial of standard and intensive systolic blood-pressure control, data on some outcome events had yet to be adjudicated and post-trial follow-up data had not yet been collected.

Methods: We randomly assigned...

Keywords/Tags:
blood-pressure trial cardiovascular hypotension stroke

Post COVID-19 Syndrome (Long Haul Syndrome): Description of a Multidisciplinary Clinic at the Mayo Clinic and Characteristics of the Initial Patient Cohort

Author/s: Vanichkachorn, G., Newcomb, R., Cowl, C. T., Trenary, M., Higgins, S., Neveau, D., Murad, M. H., Breeher, L., Miller, S.

Objective

To describe characteristics of a series of patients reporting prolonged symptoms after an infection with COVID-19.

Methods

This study describes the multidisciplinary COVID-19 Activity Rehabilitation Program (CARP), established at Mayo Clinic to evaluate and treat...

Keywords/Tags:
COVID-19 depression anxiety fatigue,

Acupuncture Treatment for Symptom Management in Atopic Dermatitis: A Study Protocol for a Randomized, Participant- and Assessor-Blind, Sham-Controlled Trial

Author/s: Park. J. G., Park, H.J., Chae, Y., Kim, Y., Lee, H., Kim, K.

Atopic dermatitis (AD) is a chronic inflammatory skin disease with persistent itching, which impairs quality of life (QoL). Although various conventional treatments for AD exist, patients with AD often seek complementary and alternative therapies when conventional therapy has failed to relieve...

Keywords/Tags:
Acupuncture Atopic Dermatitis quality of life skin disease

Get SET Early to Identify and Treatment Refer Autism Spectrum Disorder at 1 Year and Discover Factors That Influence Early Diagnosis

Author/s: Pierce, K., Gazestani, V., Bacon, E., Gyurjyan, G., Cook-Clark, T., Karins, K., Courchesne, E., Cheng, A., Barnes, C.C., Nalabolu, S., Cha, D., Arias, S., Lopez, L., Pham, C.

Objectives

To examine the impact of a new approach, Get SET Early, on the rates of early autism spectrum disorder (ASD) detection and factors that influence the screen-evaluate-treat chain.

Study design

Following Get SET Early training, 203 pediatricians...

Keywords/Tags:
screening autism Early Deteticion diagnosis

The Key Role of Nonpharmacologic Management of Cachexia in Persons With Advanced Illness: A Teachable Moment

Author/s: Kabani, A., Dy, S.M., Gupta, A.

A man in his 80s with advanced colon cancer and malignant ascites presented to the oncology clinic to discuss next steps. He reported weight loss (approximately 15 kg in 2 months), and his daughter commented on his limited appetite, weakness, and that he was “just bones.” Recent computed...

Keywords/Tags:
weight loss Colon cancer oncology nonpharmacological treatment Cachexia

Infant pacifier sanitization and risk of challenge-proven food allergy: A cohort study

Author/s: Soriano, V.X., Koplin, J.J., Forrester, M., Peters, R.L., O'Hely, M., Dharmage, S.C., Wright, R., Ranaganathan, S., Burgner, D., Thompson, K., Dwyer, T., Vuilerman, P., Ponsonby, A.

Background: Environmental microbial exposure plays a role in immune system development and susceptibility to food allergy.

Objective: We sought to investigate whether infant pacifier use during the first postnatal year, with further consideration of...

Keywords/Tags:
infant Pregnancy Pregnant Persons Mothers Allergic reactions Food Allergies

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