Clinical trials of renin-angiotensin-aldosterone system (RAAS) antagonists in heart failure with preserved ejection fraction (HFpEF) have suggested neutral results and treatment is focused on associated symptoms and comorbidities. MEDLINE and EMBASE were searched through October 2019 for...
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Statin Use Over 65 Years of Age and All-Cause Mortality: A 10-Year Follow-Up of 19 518 People
Abstract
OBJECTIVES
As life expectancy continues to rise, the burden of cardiovascular disease among older people is expected to increase, making cardiovascular prevention in older people an issue of growing interest and public health importance. We aimed to explore the long‐term...
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Summary of Revisions: Standards of Medical Care in Diabetes—2020
No abstract available.
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Canadian practice guidelines for the treatment of children and adolescents with eating disorders
Abstract
Objectives: Eating disorders are common and serious conditions affecting up to 4% of the population. The
mortality rate is high. Despite the seriousness and prevalence of eating disorders in children and adolescents, no
Canadian practice guidelines exist to facilitate...
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Diagnosis and Treatment of Clostridioides (Clostridium) difficile Infection in Adults in 2020
Not available
The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application
Abstract
Background:
A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in China in December 2019. There is limited support for many of its key epidemiologic features, including the incubation period for clinical disease (...
Clinical guideline for homeless and vulnerably housed people, and people with lived homelessness experience
KEY POINTS
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Clinical assessment and care of homeless and vulnerably housed populations should include tailoring approaches to a person’s gender, age, Indigenous heritage, ethnicity and history of trauma; and advocacy for comprehensive primary health care.
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As...
Pharmacotherapy for the Treatment of Cannabis Use Disorder: A Systematic Review
BACKGROUND:
Cannabis use disorder (CUD) is a growing concern, and evidence-based data are needed to inform treatment options.
PURPOSE:
To review the benefits and risks of pharmacotherapies for the treatment of CUD.
DATA SOURCES:
MEDLINE, PsycINFO, Cochrane...
Ameliorative Effects Of N-Acetylcysteine As Adjunct Therapy On Symptoms Of Painful Diabetic Neuropathy
PURPOSE:
Painful diabetic neuropathy (PDN) is a variant of diabetic peripheral neuropathy which is highly prevalent and distressing in diabetic patients. Despite its high burden, the optimal treatment of PDN has remained a clinical challenge. To explain the emergence and maintenance of...
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