Author/s: Ayalew Tefferi, Naseema Gangat, Giuseppe Gaetano Loscocco, Paola Guglielmelli
Importance: Essential thrombocythemia, a clonal myeloproliferative neoplasm with excessive platelet production, is associated with an increased risk of thrombosis and bleeding. The annual incidence rate of essential thrombocythemia in the US is 1.5/100 000 persons.
Observations: Patients...
Author/s: Jane S Thornton, William N Morley, Samir K Sinha
KEY POINTS
Physical activity is a modifiable risk factor for more than 30 chronic conditions relevant to the older adult; 150 minutes per week of moderate physical activity can reduce all-cause mortality by 31% compared with no physical activity.
Physical activity is one of the most...
Author/s: Ricky D Turgeon, James P McCormack, Jen Potter
Clinical question
Does sodium restriction improve outcomes in patients with chronic heart failure (CHF)?
Bottom line
In patients with CHF, restricting dietary sodium to less than 2 g/day does not reduce death or hospitalization compared with 2 to 3 g/day.
Author/s: Philippe Harris, Caroline Bissonnette, Paul Tabet, René Wittmer
Objective: To provide primary care physicians with a review of common oral white lesions and a practical management algorithm.
Sources of information: Between January and April 2024 relevant literature and clinical guidelines were searched for using the PubMed MEDLINE database with no...
Author/s: Bianca A Allison, Tracey A Wilkinson, Julie Maslowsky
This JAMA Insights explores how clinicians can effectively communicate person-centered health care information to adolescents regarding sexual and reproductive health, contraception, and sexually transmitted infection testing and treatment.
Author/s: US Preventive Services Task Force, Wanda K Nicholson, Michael Silverstein, John B Wong
Importance: Osteoporotic fractures are associated with psychological distress, subsequent fractures, loss of independence, reduced ability to perform activities of daily living, and death.
Objective: The US Preventive Services Task Force (USPSTF) commissioned a systematic review to...
Author/s: Jill Jin
This JAMA Patient Page describes osteoporosis and the US Preventive Services Task Force recommendations for screening for osteoporosis.
Author/s: Rebecca Burch
This JAMA Insights explores the prevalence of episodic and chronic migraine in adults and acute and preventive treatments for migraine, such as novel calcitonin gene-related peptide receptor antagonists.
Author/s: Courtney Romba, Jasleen Singh
Pediatricians are often the first providers to assess and treat attention-deficit/hyper-activity disorder (ADHD) in youth. While a variety of pharmacological and psychosocial interventions exist for ADHD, stimulants remain the first-line medication treatment. Many stimulant formulations now...
Author/s: Krishnansu S Tewari
Cervical cancer is preventable through vaccination and treatment of dysplasia identified on screening (cytologic screening, DNA testing for high-risk human papillomavirus subtypes, or both).
Early-stage cervical cancer is treated with open radical hysterectomy and pelvic lymphadenectomy;...