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Management of Peripheral Artery Disease

Author/s: Aman Kansal, MD, Andrew M. Davis, MD, MPH, Jennifer A. Rymer, MD, MBA

This JAMA Clinical Guidelines Synopsis summarizes the American College of Cardiology and American Heart Association’s 2024 guidelines on management of lower extremity peripheral artery disease.
Keywords/Tags:
guidelines surgery vascular surgery peripheral arterial disease Cardiology

Inhaled Pharmacotherapy for Stable COPD

Author/s: Nathan C Nowalk, Andrew M Davis, Krysta S Wolfe

This JAMA Clinical Guidelines Synopsis summarizes the 2025 Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations for inhaled pharmacotherapy for stable COPD.
Keywords/Tags:
lung disease copd

Diagnosis and Treatment of Type 2 Diabetes in Adults A Review

Author/s: Rita R Kalyani, Joshua J Neumiller, Nisa M Maruthur, Deborah J Wexler

Importance: Type 2 diabetes involves progressive loss of insulin secretion from pancreatic β cells in the setting of insulin resistance and manifests clinically as hyperglycemia. Type 2 diabetes accounts for 90% to 95% of all cases of diabetes globally, with estimates ranging from 589 million to...

Keywords/Tags:
diabetes type 2 diabetes treatment

Understanding and Managing Headaches in Children and Teens

Author/s: Cynthia-Mae M Hunt, Lindsay A Thompson

This JAMA Pediatrics Patient Page discusses symptoms and treatment of headaches in children and teens.
Keywords/Tags:
children teens headaches

New Frontier, New Challenges—Recognizing and Managing Adverse Effects of Antiamyloid Therapies

Author/s: Megan A Rech, Neelum T Aggarwal, Ula Hwang

This clinical insight discusses the diagnosis and management of adverse effects of antiamyloid therapies and what medications require consideration or avoidance.
Keywords/Tags:
antiamyloid therapies

Early Invasive or Conservative Strategies for Older Patients With Acute Coronary Syndromes: A Meta-Analysis

Author/s: Rohin K Reddy, David Koeckerling, Christian Eichhorn, Yasser Jamil, Maddalena Ardissino, Volker Braun, Haitham Abu Sharar, Norbert Frey, James P Howard, Yousif Ahmad

Importance: The optimal management strategy for older patients who present with acute coronary syndrome (ACS) remains unclear due to a paucity of randomized evidence. New large and longer-term randomized data are available.

Objective: To test the association of an early invasive strategy...

Keywords/Tags:
stroke older patients heart heart failure

Occupational Heat-Related Illness

Author/s: June T Spector, Coralynn S Sack, David K Bonauto

This JAMA Insights proposes solutions to help reduce the risk of heat-related illnesses among workers.
Keywords/Tags:
heat illnesses occupational disease

Adrenal Insufficiency in Adults: A Review

Author/s: Anand Vaidya, James Findling, Irina Bancos

Importance: Adrenal insufficiency is a syndrome of cortisol deficiency and is categorized as primary, secondary, or glucocorticoid induced. Although primary and secondary adrenal insufficiency are rare, affecting less than 279 per 1 million individuals, glucocorticoid-induced adrenal...

Keywords/Tags:
adrenal adrenal insufficiency Adults

Surgery versus corticosteroid injection for carpal tunnel syndrome (DISTRICTS): an open-label, multicentre, randomised controlled trial

Author/s: Wijnand A C Palmbergen, Roy Beekman, A Marijne Heeren, Bart F L van Nuenen, Tim W H Alleman, Esther Verstraete, Korné Jellema, Wim I M Verhagen, Leo H Visser, Godard C W de Ruiter, Diederik van de Beek, Corianne A J M de Borgie, Johannes A Bogaards, Rob M A de Bie, Camiel Verhamme, Dutch CTS study group

Background: Surgery and corticosteroid injections are established treatments for carpal tunnel syndrome, but the optimal treatment strategy remains unclear. This study aimed to compare starting treatment with surgery versus starting with a corticosteroid injection.

Methods: We conducted...

Keywords/Tags:
Netherlands middle aged Humans Adrenal Cortex Hormones* / administration & dosage Adrenal Cortex Hormones* / therapeutic use Carpal Tunnel Syndrome* / drug therapy Carpal Tunnel Syndrome* / surgery Carpal Tunnel Syndrome* / therapy Decompression Surgical* / methods

What Is a Cardiac CT Calcium Score?

Author/s: Kristin L Walter

This JAMA Patient Page describes the use of cardiac computed tomography scans to look for calcium in the coronary arteries as a predictor of future atherosclerotic cardiovascular disease events.
Keywords/Tags:
cardiac computed tomography calcium coronary arteries Atherosclerotic Cardiovascular Disease Coronary Vessels

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