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Impact of Biopsy Technique on Clinically Important Outcomes for Cutaneous Melanoma: A Systematic Review and Meta-analysis
We performed a systematic review and meta-analysis to examine the relationship between the type of biopsy technique employed in the diagnosis of cutaneous melanoma and 4 clinically important outcomes: melanoma-specific mortality, all-cause mortality, Breslow tumor depth, or melanoma recurrence....
Is the antibody testing for COVID-19 in the general population a useful diagnostic tool?
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Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older
Importance: Data are limited regarding statin therapy for primary prevention of atherosclerotic cardiovascular disease (ASCVD) in adults 75 years and older.
Objective: To evaluate the role of statin use for mortality and primary prevention of ASCVD in...
Forecasting Opioid Use Disorder at 25 Years of Age in 16-Year Old Adolescents
Objective
t To evaluate the accuracy of detecting 16 year old male (N=465) and female (N=162) youths who subsequently manifest opioid use disorder (OUD) at 25 years of age. We hypothesized that the combined measures of two components of etiology, heritable risk and substance use...
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Acupuncture for Recurrent Urinary Tract Infection in Women: A Systematic Review and Meta-Analysis
Abstract
Background: Increasing antibiotic resistance has motivated interest in non-antibiotic prophylaxis of recurrent urinary tract infections (rUTI).
Objectives: To conduct a systematic review of the current state of evidence of acupuncture for...
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Association Between Oral Corticosteroid Bursts and Severe Adverse Events: A Nationwide Population-Based Cohort Study
Abstract
Background: Long-term use of oral corticosteroids has known adverse effects, but the risk from brief oral steroid bursts (≤14 days) is largely unknown.
Objective: To examine the associations between steroid bursts and severe adverse events...
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Multisystem Inflammatory Syndrome in U.S. Children and Adolescents
Abstract
BACKGROUND
Understanding the epidemiology and clinical course of multisystem inflammatory syndrome in children (MIS-C) and its temporal association with coronavirus disease 2019 (Covid-19) is important, given the clinical and public health implications of the syndrome....
Does Adding of Hydroxychloroquine to the Standard Care Provide Any Benefit in Reducing the Mortality Among COVID-19 Patients?: A Systematic Review
Hydroxychloroquine has been promoted for its use in treatment of COVID-19 patients based on in-vitro evidences. We searched the databases to include randomized and observational studies evaluating the effect of Hydroxychloroquine on mortality in COVID-19 patients. The outcome was summarized as...
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