Diagnosis and acute management of migraine
Date Added: 
    February 8, 2023
      Journal/Publication: 
    CMAJ
      Publisher: 
    CMA Impact Inc
      Publication Date: 
    January 30, 2023
      Issue: 
    4
      Volume: 
    195
      Pages: 
    E153-E158
      Type: 
    Meta-analyses, Reviews, and Guidelines
      Format: 
    Article
      DOI (1): 
    10.1503/cmaj.211969
      PMID (1): 
    36717129
      Abstract
Migraine is a leading cause of disability across all age groups.
• Routine imaging is not recommended in patients with migraine
who have no red flags, atypical symptoms or abnormal findings
on neurologic examination.
• A stratified approach for acute migraine treatment empowers
patients to choose from different treatment options
depending on attack symptoms and severity and encourages
patients to combine medications from different classes.
• Effective acute migraine treatment includes acetaminophen,
nonsteroidal anti-inflammatory drugs and triptans.
• Ubrogepant and rimegepant are new, effective migraine
treatments, suitable for patients with cardiovascular disease in
whom triptans are contraindicated.
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RPR Commentary
A concise review of the presumed cause and treatment of migraine headaches. James W. Mold, MD, MPH