Many trials of naltrexone have been carried out in alcohol-dependent patients. This paper is aimed to systematically review its benefits, adverse effects, and discontinuation of treatment. We assessed and extracted the data of double-blind, randomized controlled trials (RCTs) comparing...
Recent Resources
Naltrexone for the treatment of alcoholism: A meta-analysis of randomized controlled trials
Brief physician advice for problem alcohol drinkers. A randomized controlled trial in community-based primary care practices
OBJECTIVE:
Project TrEAT (Trial for Early Alcohol Treatment) was designed to test the efficacy of brief physician advice in reducing alcohol use and health care utilization in problem drinkers.
DESIGN:
Randomized controlled clinical trial with 12-month follow-up.
...
Brief physician and nurse practitioner-delivered counseling for high-risk drinking. Results at 12-month follow-up
BACKGROUND:
The objective of this study was to determine the effects of a brief primary care provider-delivered counseling intervention on the reduction of alcohol consumption by high-risk drinkers. The intervention was implemented as part of routine primary care medical practice.
...
Adapting Screening, Brief Intervention, and Referral to Treatment for Alcohol and Drugs to Culturally Diverse Clinical Populations
OBJECTIVES:
To review the literature on the screening, brief intervention, and referral to treatment (SBIRT) approach to alcohol and drug use with racial and ethnic subgroups in the United States and to develop recommendations for culturally competent SBIRT practice.
METHODS:
...Primary care intervention to reduce alcohol misuse ranking its health impact and cost effectiveness
BACKGROUND:
The U.S. Preventive Services Task Force (USPSTF) has recommended screening and behavioral counseling interventions in primary care to reduce alcohol misuse. This study was designed to develop a standardized rating for the clinically preventable burden and cost effectiveness of...
Helping Patients Who Drink Too Much: A Clinician's Guide
Why screen for heavy drinking?
- At-risk drinking and alcohol problems are common. About 3 in 10 U.S. adults drink at levels that elevate their risk for physical, mental health, and social problems. Of these heavy drinkers, about 1 in 4 currently has alcohol abuse or...
A meta-analysis of alcohol consumption and the risk of 15 diseases
BACKGROUND:
To compare the strength of evidence provided by the epidemiological literature on the association between alcohol consumption and the risk of 14 major alcohol-related neoplasms and non-neoplastic diseases, plus injuries.
METHODS:
A search of the epidemiological...
Planning and Implementing Screening and Brief Intervention for Risky Alcohol Use
Like hypertension or tobacco screening, alcohol screening and brief intervention (alcohol SBI) is a clinical preventative service. It identifies and helps patients who may be drinking too much. It involves:
- A validated set of screening questions to identify patients' drinking...
Addressing Alcohol Use: Practice Manual
Risky alcohol use, defined as any level of alcohol consumption which increases the risk of harm to oneself or others, is both a substance use disorder and medical issue. Recognized as one of the leading preventable causes of death, risky alcohol use leads to over 88,000 deaths each year in the...
Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review
IMPORTANCE:
Alcohol consumption is associated with 88 000 US deaths annually. Although routine screening for heavy alcohol use can identify patients with alcohol use disorder (AUD) and has been recommended, only 1 in 6 US adults report ever having been asked by a health professional about...