IMPORTANCE Hypertension is a prevalent condition that affects approximately 45% of the adult US population and is the most commonly diagnosed condition at outpatient office visits. Hypertension is a major contributing risk factor for heart failure, myocardial infarction, stroke, and chronic...
Recent Resources
The Key Role of Nonpharmacologic Management of Cachexia in Persons With Advanced Illness: A Teachable Moment
A man in his 80s with advanced colon cancer and malignant ascites presented to the oncology clinic to discuss next steps. He reported weight loss (approximately 15 kg in 2 months), and his daughter commented on his limited appetite, weakness, and that he was “just bones.” Recent computed...
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Non-steroidal anti-inflammatory drugs for acute low back pain
Background: Acute low back pain (LBP) is a common health problem. Non-steroidal anti-inflammatory drugs (NSAIDs) are often used in the treatment of LBP, particularly in people with acute LBP. In 2008, a Cochrane Review was published about the efficacy of NSAIDs for LBP...
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Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians
Description: Antimicrobial overuse is a major health care issue that contributes to antibiotic resistance. Such overuse includes unnecessarily long durations of antibiotic therapy in patients with common bacterial infections, such as acute bronchitis with chronic obstructive...
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Safety and tolerability of natural and synthetic cannabinoids in adults aged over 50 years: A systematic review and meta-analysis
Background: Cannabinoid-based medicines (CBMs) are being used widely in the elderly. However, their safety and tolerability in older adults remains unclear. We aimed to conduct a systematic review and meta-analysis of safety and tolerability of CBMs in adults of age ≥50 years....
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Management of Persistent Pain in the Older Patient A Clinical Review
Importance: Persistent pain is highly prevalent, costly, and frequently disabling in later life.
Objective: To describe barriers to the management of persistent pain among older adults, summarize current management approaches, including pharmacologic and...
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Screening for Lung Cancer US Preventive Services Task Force Recommendation Statement
Importance: Lung cancer is the second most common cancer and the leading cause of cancer death in the US. In 2020, an estimated 228 820 persons were diagnosed with lung cancer, and 135 720 persons died of the disease. The most important risk factor for lung cancer is smoking....
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Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke: A Review
Importance: Stroke is the fifth leading cause of death and a leading cause of disability in the United States, affecting nearly 800 000 individuals annually.
Observations: Sudden neurologic dysfunction caused by focal brain ischemia with imaging evidence...
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Understanding Suicide Risk And Prevention
KEY POINTS:
- Suicide rates have been rising during the past several years, but suicide is preventable.
- There are many known risk factors for suicide, but the predictive utility of any single risk factor is low, requiring a focus on population-level rather than...
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Mobile phone text messaging and app-based interventions for smoking cessation
Background: Mobile phone-based smoking cessation support (mCessation) offers the opportunity to provide behavioural support to those who cannot or do not want face-to-face support. In addition, mCessation can be automated and therefore provided affordably even in resource-poor...
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