1. Home
  2. Meta-analyses, Reviews, and Guidelines
  3. Recent Resources

Recent Resources

A challenging diagnosis: hereditary angioedema presenting during pregnancy

Author/s: Chair, I., Lacuesta, G., Nash, C. M., Cook, V.

• Hereditary angioedema (HAE) is a rare autosomal dominant
disorder characterized by recurrent episodes of painful (and
usually asymmetric) swelling without urticaria that leads to
substantial morbidity and even mortality (in the case of
laryngeal involvement) if left...

Keywords/Tags:
abdominal pain Morbidity diagnosis, differential Hereditary angioedema (HAE) female

Conservative interventions for treating urinary incontinence in women: an Overview of Cochrane systematic reviews

Author/s: Todhunter-Brown, A., Hazelton, ,C., Campbell, P., Elders, A., Hagen, S., McClurg, D.

Background: Urinary incontinence (UI) is the involuntary loss of urine and can be caused by several different conditions. The common types of UI are stress (SUI), urgency (UUI) and mixed (MUI). A wide range of interventions can be delivered to reduce the symptoms of UI in women. Conservative...

Keywords/Tags:
weight loss stress urinary incontinence urgency urinary incontinence mixed urinary incontinence quality of life

Use of Recommended Health Care Measures to Prevent Selected Complications of Sickle Cell Anemia in Children and Adolescents — Selected U.S. States, 2019

Author/s: Schieve, L. A., Simmons, G. M., Payne, A. B., Abe, K., Hsu, L. L., Hulihan, M., Pope, S., Rhie, S., Dupervil, B., Hooper, W. C.

Introduction: Sickle cell disease (SCD), a group of inherited blood cell disorders that primarily affects Black or African American persons, is associated with severe complications and a >20-year reduction in life expectancy. In 2014, an expert panel convened by the National Heart, Lung, and...

Keywords/Tags:
health personnel African Americans medicaid child blood cells

The Management of Major Depressive Disorder: Synopsis of the 2022 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline

Author/s: McQuaid, J. R., Buelt, A., Capaldi, V., Fuller, M., Issa, F., Lang, A. E., Hoge, C., Sall, J., Wiechers, I. R., Williams, S.

Abstract
Description: In February 2022, the U.S. Department of Veterans Affairs (VA) and U.S. Department of Defense (DoD) approved a joint clinical practice guideline (CPG) for the management of major depressive disorder (MDD). This synopsis summarizes key recommendations.

Methods:...

Keywords/Tags:
Department of Veterans Affairs veterans Department of Defense Algorithms alternative therapies

Management of Heart Failure

Author/s: Belkin, M. N., Cifu, A. S., Pinney, S.

GUIDELINE TITLE 2022 American College of Cardiology
(ACC)/American Heart Association AHA)/Heart Failure
Society of America (HFSA) Guidelines for the Management
of Heart Failure
RELEASE DATE April 1, 2022
PRIOR VERSIONS 2017 ACC/AHA/HFSA Focused Update
of the...

Keywords/Tags:
Stroke Volume American Heart Association Cardiology heart failure Sodium

Treatment of Clostridioides difficile Infection

Author/s: Sehgal, K., Cifu, A. S., Khanna, S.

Clostridioides difficile infection is a common nosocomial and community-acquired cause of diarrhea, with an estimated 453 000 cases per year in the United States.1 Treatment of CDI is based on severity and recurrence risk.
Keywords/Tags:
Humans United States Diarrhea C. diff infections

Diagnosis and Treatment of Myelodysplastic Syndromes: A Review

Author/s: Sekeres, M. A., Taylor, J.

Importance Myelodysplastic neoplasms (MDS), formerly known as myelodysplastic syndromes, are clonal hematopoietic malignancies that cause morphologic bone marrow dysplasia along with anemia, neutropenia, or thrombocytopenia. MDS are associated with an increased risk of acute myeloid leukemia (...

Keywords/Tags:
Leukemia Hematinics Prognosis Myedysplastic syndromes drug therapy

Pre-exposure prophylaxis for HIV: effective and underused

Author/s: Hempel, A., Biondi, M. J., Baril, J., Tan, D. H. S.

Pre-exposure prophylaxis (PrEP) is a highly effective modality for HIV prevention that can be prescribed by generalists.

Pre-exposure prophylaxis should be offered to patients who are at high risk of HIV exposure, including gay, bisexual and other men who have sex with men (GBM), women...

Keywords/Tags:
Follow-Up Studies Substance Abuse, intravenous Canada sexually transmitted diseases Drug users

Management of acute diverticulitis

Author/s: Zondervan, N., Snelgrove, R., Bradley, N.

1 Emergency department visits and hospital admissions for acute
diverticulitis have increased
Emergency department visits for acute diverticulitis increased by 26.8% to
113.9 visits per 100 000 from 2006 to 2013 in the United States.1
Hospital admissions for...

Keywords/Tags:
Colonoscopy abscess Anti-Bacterial Agents Bacterial translocation sepsis

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

Author/s: Humbert, M., Kovacs, G., Hoeper, M. M., Badagliacca, R., Berger, R. M. F., Brida, M., Carlsen, J., Coats, A. J. S., Escribano-Subias, P., Ferrari, P., Ferreira, D. S., Ghofrani, H. A., Ginnakoulas, G., Kiely, D. G., Mayer, E., Meszaros, G., Nagavci, B., Olsson, K. M., Pepke-Zaba, J., Quint, J. K., Rådegran, G., Simonneau, G., Sitbon, O., Tonia, T., Toshner, M., Vachiery, J. L., Noordegraaf, A. V., Delcroix, M., Rosenkranz, S., ESC/ERS Scientific Document Group

Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple clinical conditions and may be associated with a variety of cardiovascular and respiratory diseases. The complexity of managing PH requires a multifaceted, holistic, and multidisciplinary approach, with active...

Keywords/Tags:
Chronic Thrombo-embolic pulmonary hypertension clinical practice cardiovascular respiratory disease Pathophysiological disorder

RPR User Guide

Research-to-Practice-to-Research (RPR) Exchange

If you need assistance with the RPR Exchange, please use the QOS form and leave a question or suggestion.  We review them regularly and will get back with you.  If you  need general information about using the RPR Exchange, the User Guide is available on-line.  You might also find the FAQs useful for some of the common questions RPR users have.