Importance: Hypothyroidism is a disease of thyroid hormone deficiency. The prevalence ranges from 0.3% to 12% worldwide, depending on iodine intake, and it is more common in women and older adults. Untreated hypothyroidism can cause serious health complications such as heart failure and myxedema...
Recent Resources
Self-Collection for Cervical Cancer Screening in a Safety-Net Setting: The PRESTIS Randomized Clinical Trial
Importance There are limited data on the effectiveness of mailed self-collection to increase cervical cancer screening (CCS) participation in underresourced health care settings.
Objective To compare the effectiveness of mailed self-collection kits, with and without patient navigation,...
Keywords/Tags:
Self-Collection for Cervical Cancer Screening in a Safety-Net Setting: The PRESTIS Randomized Clinical Trial
Importance There are limited data on the effectiveness of mailed self-collection to increase cervical cancer screening (CCS) participation in underresourced health care settings.
Objective To compare the effectiveness of mailed self-collection kits, with and without patient navigation,...
Keywords/Tags:
Cannabidiol and Liver Enzyme Level Elevations in Healthy Adults: A Randomized Clinical Trial
Importance The wide use of unregulated cannabidiol (CBD) products among consumers raises safety concerns. Most research on CBD has studied the relatively high doses used by patients taking prescription CBD. However, limited safety data are available at lower doses.
Objective To study...
Keywords/Tags:
Testosterone Treatment in Middle-Aged and Older Men with Hypogonadism
•
In clinical trials involving middle-aged and older men with hypogonadism, testosterone treatment led to improved sexual activity and libido, correction of anemia, and modestly improved energy, mood, and walking ability. (The following key points also refer to findings from clinical...
Keywords/Tags:
Long-Term Anticoagulation Discontinuation After Catheter Ablation for Atrial Fibrillation: The ALONE-AF Randomized Clinical Trial
Importance: Data from randomized clinical trials on a long-term anticoagulation strategy for patients after catheter-based ablation for atrial fibrillation (AF) are lacking.
Objective: To evaluate whether discontinuing oral anticoagulant therapy provides superior clinical outcomes...
Keywords/Tags:
Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation
Background: The appropriate antithrombotic regimen for patients with chronic coronary syndrome who are at high atherothrombotic risk and receiving long-term oral anticoagulation remains unknown.
Methods: We conducted a multicenter, double-blind, randomized, placebo-controlled trial in...
Keywords/Tags:
Efficacy and Safety of Seltorexant in Insomnia Disorder: A Randomized Clinical Trial
Importance: Existing pharmacological treatments for insomnia have significant limitations.
Objective: To assess the effective dose range, safety, and tolerability of the novel selective orexin-2 receptor antagonist seltorexant in insomnia disorder.
Design, setting, and participants...
Keywords/Tags:
Venomous Snakes and Snakebites
This JAMA Patient Page describes the venomous snakes found in the US as well as snakebite symptoms, treatment, and prevention.
Keywords/Tags:
Restless Legs Syndrome in Adult Primary Care
Restless Legs Syndrome (RLS) or Willis‑Ekbom Disease is a sensorimotor condition marked by an irresistible need to move the legs, typically accompanied by uncomfortable sensations that peak during periods of rest and disrupt nightly sleep. Early identification in primary care is essential, as...
Keywords/Tags: