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Obesity Treatment, Beyond the Guidelines: Practical Suggestions for Clinical Practice

Author/s: Kahan, Scott, Manson, JoAnn E.

No abstract available.
Keywords/Tags:
obesity primary care overweight weight loss

Quick Uptakes: Taking the Uncertainty Out of Interpreting BRCA Variants

Author/s: Voelker, Rebecca

The Problem

Testing for BRCA1 and BRCA2 mutations identifies both benign and pathogenic genetic variants. But information about specific variants, particularly those of uncertain clinical significance (VUS), often isn’t systematically curated, expertly reviewed, or...

Keywords/Tags:
BRCA BRCA variants

Pharmacologic and Nonpharmacologic Treatments for Urinary Incontinence in Women: A Systematic Review and Network Meta-analysis of Clinical Outcomes

Author/s: Balk, E.M., Rofebero, V.N., Adam, G.P., Kimmel, H.J., Trikalinos, T.A., Jeppson, P.C.

BACKGROUND:

Urinary incontinence (UI), a common malady in women, most often is classified as stress, urgency, or mixed.

PURPOSE:

To compare the effectiveness of pharmacologic and nonpharmacologic interventions to improve or cure stress, urgency, or mixed UI in nonpregnant ...

Keywords/Tags:
behavioral interventions incontinence

Aspirin for the Primary Prevention of Cardiovascular Disease: Weighing Up the Evidence

Author/s: Murphy, Sean, McCarthy, Cian P., McEvoy, John W.

Aspirin is one of the most universally recognized and commonly prescribed medications worldwide. It is estimated that 48.7 million U.S. adults are taking aspirin for cardiovascular disease prevention; the majority (~73%) for primary prevention. The benefit of aspirin for secondary prevention of...

Keywords/Tags:
aspirin cardiovascular events

Exercise Videogames, Physical Activity, and Health: Wii Heart Fitness: A Randomized Clinical Trial

Author/s: Bock, Beth C., Dunsiger, Shira I., CIccolo, Joseph T., Serber, Eva R., Wu, Wen-Chih, Tilkemeier, Peter, Walaska, Kristen A., Marcus, Bess H.

INTRODUCTION:

Adults who engage in regular physical activity have lower rates of morbidity and mortality than those who do not. Exercise videogames may offer an attractive, sustainable alternative or supplement to traditional modes of exercise. This study compared exercise videogames with...

Keywords/Tags:
video games exercise physical activity

Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial

Author/s: Packer, Douglas L., Mark, Daniel B., Robb, RIchard A., Monahan, Kristi H., Bahnson, Tristram D., Poole, Jessica E., Noseworthy, Peter A., Rosenberg, Yves D., Jeffries, Neal, Mitchell, L. Brent, Flaker, Greg C., Pokushalov, Evgeny, Romanov, ALexander, Bunch, T. Jared, Noelker, Georg, Ardashev, Andrey, Revishvili, Amiran, Wilber, David J., Cappato, Riccardo, Kuck, Karl-Heinz, Hindricks, Gerhard, Davies, D. Wyn, Kowey, Peter R., Naccarelli, Gerald V., Reiffel, James A., Piccini, Jonathan P., Silverstein, Adam P., Al-Khalidi, Hussein R., Lee, Kerry L.

IMPORTANCE:

Catheter ablation is effective in restoring sinus rhythm in atrial fibrillation (AF), but its effects on long-term mortality and stroke risk are uncertain.

OBJECTIVE:

To determine whether catheter ablation is more effective than conventional medical therapy for...

Keywords/Tags:
symptomatic atrial fib atrial fib cather ablation

Effect of Catheter Ablation vs Medical Therapy on Quality of Life Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial

Author/s: Mark, Daniel B., Anstrom, Kevin J., Sheng, Shubin, Piccini, Jonathan P., Baloch, Khaula N., Monahan, Kristi H., Daniels, Melanie R., Bahnson, Tristram D., Poole, Jeanne E., Rosenberg, Yves, Lee, Kerry L., Packer, Douglas L.

IMPORTANCE:

Catheter ablation is more effective than drug therapy in restoring sinus rhythm in patients with atrial fibrillation (AF), but its incremental effect on long-term quality of life (QOL) is uncertain.

OBJECTIVE:

To determine whether catheter ablation is more...

Keywords/Tags:
atrial fib catheter ablation medical therapy QOL

Reducing Risk for Patients on Long-Term Opioids

Author/s: National Resource Center for Academic Detailing

Safer prescribing of opioids: algorithm for managing patients already receiving long-term opioids.
Keywords/Tags:
opioids long-term opioids risk reduction

Pain and Opioid Management in Primary Care

Author/s: National Resource Center for Academic Detailing

Oklahoma ranked 5th nationally in rates of opioid prescribing in 2016, with 97.9 opioid prescriptions per 100 people. Opioids account for the majority of prescription drug-related overdose deaths. Despite recent declines, deaths from opioids remain common.
Keywords/Tags:
opioids pain management

Pulmonary Health Effects of Agriculture

Author/s: Nordgren, Tara M., Bailey, Kristina L.

PURPOSE OF REVIEW:

Occupational exposures in the agricultural industry are associated with numerous lung diseases, including chronic obstructive pulmonary disease, asthma, hypersensitivity pneumonitis, lung cancer, and interstitial lung diseases. Efforts are ongoing to ascertain...

Keywords/Tags:
pulmonary disease agriculture farmers pulmonary disorders

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