This Clinical Insights discusses special considerations in recurrent urinary tract infection diagnosis and management in older women.
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Bacterial vaginosis
Bacterial vaginosis is the most common cause of abnormal vaginal discharge, affecting 23%–30% of reproductive-aged people
Bacterial vaginosis is caused by a disrupted vaginal microbiome balance. Symptoms include itch, dysuria, and a thin, grey discharge with a “fishy” odour, particularly...
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Opioid-Induced Adrenal Insufficiency
A woman in her 40s with opioid use disorder receiving methadone (70 mg daily) was admitted for extended antibiotic treatment for methicillin-resistant Staphylococcus aureus bacteremia. She had been taking methadone at varying doses (ranging from 15 to 70 mg daily) for 15 years.
Following...
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Pediatric sialorrhea (drooling)
Sialorrhea is common in children with neurologic impairment
Sialorrhea can be normal in children with typical development until age 4 years. It occurs in as many as 44% of children with cerebral palsy.1 It typically results from poor oral motor control and fluctuates alongside the child’s...
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Exercise as a treatment for depression
Exercise effectively treats depression and may decrease suicide attempts
A 2023 meta-analysis of randomized controlled trials (RCTs) found that supervised, group or non-group, moderate- or vigorous-intensity, aerobic or resistance exercises (excluding mind–body activities such as yoga)...
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Screening for Breast Cancer: US Preventive Services Task Force Recommendation Statement
Importance: Among all US women, breast cancer is the second most common cancer and the second most common cause of cancer death. In 2023, an estimated 43 170 women died of breast cancer. Non-Hispanic White women have the highest incidence of breast cancer and non-Hispanic Black women have the...
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Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
Background: Osteoporosis is an abnormal reduction in bone mass and bone deterioration, leading to increased fracture risk. Etidronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts - bone cells that break down...
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Interstitial Lung Disease: A Review
Importance: Interstitial lung disease (ILD) consists of a group of pulmonary disorders characterized by inflammation and/or fibrosis of the lung parenchyma associated with progressive dyspnea that frequently results in end-stage respiratory failure. In the US, ILD affects approximately 650 000...
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Measles
Canada has had measles elimination status since 1998 but remains vulnerable to outbreaks
Increased measles activity globally raises the risk of travel-related cases in Canada, which can spread rapidly in underimmunized communities.
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Arteriovenous Access for Hemodialysis: A Review
Importance: Hemodialysis requires reliable vascular access to the patient’s blood circulation, such as an arteriovenous access in the form of an autogenous arteriovenous fistula or nonautogenous arteriovenous graft. This Review addresses key issues associated with the construction and...
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