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USPSTF Recommendation: Preexposure Prophylaxis to Prevent Acquisition of HIV

Author/s: Wong, John B.

Interview with John B. Wong, MD, USPSTF member and coauthor of Preexposure Prophylaxis to Prevent Acquisition of HIV: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.

Stress urinary incontinence and synthetic mesh midurethral slings in women

Author/s: Kanji, Sarah, Clancy, Aisling A.

Stress urinary incontinence has a prevalence of 10%–40% and is considered severe in 3%–17% of women worldwide.1 Diagnosis involves demonstrating involuntary urine leakage with increases in intra-abdominal pressure (e.g., exercising, coughing). On history, it is important to differentiate this...

Keywords/Tags:
female Surgical treatment suburethral slings

Comparative Efficacy of Pharmacological Treatments for Acne Vulgaris: A Network Meta-Analysis of 221 Randomized Controlled Trials

Author/s: Huang, Chung-Yen, Chang, I-Jing, Bolick, Nicole, Hsu, Wan-Ting, Su, Chin-Hua, Hsieh, Tyng-Shiuan, Huang, I-Hsuan, Lee, Chien-Chang

PURPOSE Acne is an extremely common skin disease with an estimated global prevalence of 9.4%. We aim to provide comprehensive comparisons of the common pharmacological treatments for acne.

METHODS Randomized controlled trials comparing the efficacy of pharmacological therapies for acne...

Keywords/Tags:
randomized control trial adolescent acne

Pelvic organ prolapse

Author/s: Lee, Patricia E., Mcleod, Laura

Prolapse is found in 41%–50% of adult females, with symptoms of pelvic pressure and vaginal bulge sensation reported by 3%–6% of adult females. Prolapse is diagnosed and staged with physical examination based on the maximum descent of vaginal tissue (anterior, posterior or apex) on Valsalva...

Keywords/Tags:
pelvic organ female postmenopause

Oral Nonprescription Pain Medications for Adults

Author/s: Vordenberg, Sarah E.

Some prescription pain medications prescribed by doctors also include a nonprescription pain medication. Therefore, to avoid taking more than the recommended amount of acetaminophen or an NSAID, it is important to tell your doctor if you are taking over-the-counter pain medications in addition...

Keywords/Tags:
patient education naproxene ibuprofen

Low-Dose Aspirin and the Risk of Stroke and Intracerebral Bleeding in Healthy Older People

Author/s: Cloud, Geoffrey, Williamson, Jeff D., Le Thi Phuong Thao

Importance Low-dose aspirin has been widely used for primary and secondary prevention of stroke. The balance between potential reduction of ischemic stroke events and increased intracranial bleeding has not been established in older individuals.

Objective To establish the risks of...

Keywords/Tags:
elderly stroke risk low-dose aspirin

Folic Acid Supplementation to Prevent Neural Tube Defects: Preventive Medication

Recommendations made by the USPSTF are independent of the U.S. government. They should not be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services.
Keywords/Tags:
Pregnant Persons Folic Acid dietary supplements

What Parents Should Know About Bugs and Bug Repellents

Author/s: Henderson, Emily J., Rutt, jennifer N., Albertini, Laurie W.

What Parents Should Know About Bugs and Bug Repellents
Keywords/Tags:
children parents

Management of Latent Tuberculosis Infection

Author/s: Kim, S., Thal, R., Szwarko, D.

In theUS, approximately 13million people have latent tuberculosis infection (LTBI),definedaspeoplewhoareinfectedwithMycobacterium
tuberculosiswho do not have symptoms and do not transmit the disease.Without treatment, approximately 5% to 10% of immunocompetent personswithLTBI develop...

Keywords/Tags:
prednisone Tuberculin Centers for Disease Control and Prevention, U.S. tuberculosis Infection

Bempedoic Acid for Primary Prevention of Cardiovascular Events in Statin-Intolerant Patients

Author/s: Nissen, S. E., Menon, V., Nicholls, S. J., Brennan, D., Laffin, L., Ridker, P., Ray, K. K., Mason, D., Kastelein, J. J. P., Cho, L., Libby, P., Li, N., Foody, J., Louie, M. J., Lincoff, A. M.

Importance: The effects of bempedoic acid on cardiovascular outcomes in statin-intolerant patients without a prior cardiovascular event (primary prevention) have not been fully described.

Objective: To determine the effects of bempedoic acid on cardiovascular outcomes in primary...

Keywords/Tags:
Cardiovascular Diseases stroke drug therapy bempedoic acid statin-intolerant patients

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