We aimed to evaluate the association between vitamin D deficiency and diabetic foot ulcer (DFU) in patients with diabetes. Pubmed, EMBASE, BIOSIS, the Cochrane Library, and Web of Knowledge, last updated in July 2018, were searched. We assessed eligible studies for the association between...
Library & Search Results
The 10 Building Blocks of High-Performing Primary Care
Our experiences studying exemplar primary care practices, and our work assisting other practices to become more patient centered, led to a formulation of the essential elements of primary care, which we call the 10 building blocks of high-performing primary care. The building blocks include 4...
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What Are Polygenic Scores and Why Are They Important?
Mendelian disorders and monogenic traits result from combinations of variants in 1 or a few genes that have a large effect on the propensity...
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Screening for Breast Cancer in Average-Risk Women: A Guidance Statement From the American College of Physicians
Description:
The purpose of this guidance statement is to provide advice to clinicians on breast cancer screening in average-risk women based on a review of existing guidelines and the evidence they include.
Methods:
This guidance statement is derived from an appraisal of...
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Early Subthreshold Aerobic Exercise for Sport-Related Concussion: A Randomized Clinical Trial
IMPORTANCE:
Sport-related concussion (SRC) is a significant public health problem without an effective treatment.
OBJECTIVE:
To assess the effectiveness of subsymptom threshold aerobic exercise vs a placebo-like stretching program prescribed to adolescents in the acute phase...
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Adverse Effects of First-line Pharmacologic Treatments of Major Depression in Older Adults
Objective. To assess selected adverse events of antidepressants in the treatment of major depressive disorder (MDD) in adults 65 years old or older. Antidepressants included in this review, as determined by expert opinion, are selective serotonin reuptake inhibitors (SSRIs),...
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Terminating a Patient: Is It Time to Part Ways?
Many family physicians chose the specialty of family medicine because of the value placed on the therapeutic relationship between the patient and the physician. When that relationship is significantly or repeatedly challenged, family physicians feel it deeply, and it’s not always clear how best...
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Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review
BACKGROUND:
Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent and a major cause of physical dysfunction and psychosocial distress. Exercise is recommended to reduce joint pain and improve physical function, but the effect of exercise on psychosocial function...
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Concussion Incidence, Duration, and Return to School and Sport in 5- to 14-Year-Old American Football Athletes
OBJECTIVE:
To collect prospective data on concussion incidence, risk factors, duration of symptoms, and return to school and sport in 5- to 14-year-old American football participants.
STUDY DESIGN:
We conducted a prospective cohort study over 2 years collecting data during...
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Replacing sedentary time with physical activity: a 15-year follow-up of mortality in a national cohort
BACKGROUND:
Sedentary behavior is associated with health risks in adults. The potential benefits of reducing sedentary time may be dependent not only on decrease per se, but also on the type of activity it replaces. Few longitudinal studies have investigated the effects on mortality when...
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