The authors review studies on key issues in women’s health with potential impact on internal medicine practice. The reviewed articles discuss cardiovascular disease risks, bone health, breast cancer genetics, cervical cancer prevention, depression in the peripartum period, pelvic pain, and...
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Gabapentin Increasingly Implicated in Overdose Deaths
Gabapentin Increasingly Implicated
in Overdose Deaths
Postmortem toxicology tests detected gabapentin in almost 1 in 10 US overdose deaths
between 2019 and 2020.In about half of the
cases, a medical examiner or coroner ruled
the drug was a cause of the death,...
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Effect of Physical Therapy vs Arthroscopic Partial Meniscectomy in People With Degenerative Meniscal Tears: Five-Year Follow-up of the ESCAPE Randomized Clinical Trial
Importance: There is a paucity of high-quality evidence about the long-term effects (ie, 3-5 years and beyond) of arthroscopic partial meniscectomy vs exercise-based physical therapy for patients with degenerative meniscal tears.
Objectives: To compare the 5-year effectiveness of...
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Effect of Varenicline Added to Counseling on Smoking Cessation Among African American Daily Smokers The Kick It at Swope IV Randomized Clinical Trial
Importance: African American smokers have among the highest rates of tobacco-attributable morbidity and mortality in the US, and effective treatment is needed for all smoking levels.
Objectives: To evaluate the efficacy of varenicline vs placebo among African American adults who are light...
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Long-Acting Reversible Contraception With Contraceptive Implants and Intrauterine Devices
Long-acting reversible contraception (LARC), including contraceptive implants and intrauterine devices (IUDs), is highly effective, with typical-use failure rates of less than 1 pregnancy per 100 person-years of use.1 Fertility returns rapidly after discontinuation of LARC.
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The effect of lead exposure on IQ test scores in children under 12 years: a systematic review and meta-analysis of case-control studies
An inevitable exposure to the toxic heavy metal such as lead in our environmental can have irreversible effects on children's mental performance.In this study, 3316 children in 8 case-control studies were selected for review. The case group was exposed to a concentration of lead above 10 μg/dL,...
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Cannabis-Based Products for Chronic Pain : A Systematic Review
Background: Contemporary data are needed about the utility of cannabinoids in chronic pain.
Purpose: To evaluate the benefits and harms of cannabinoids for chronic pain.
Data sources: Ovid MEDLINE, PsycINFO, EMBASE, the Cochrane Library, and Scopus to January 2022.
Study...
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Chronic anal pain: A review of causes, diagnosis, and treatment
Chronic anal pain is diffi cult to diagnose and treat, especially with no obvious anorectal cause apparent on clinical examination. This review identifi es 3 main diagnostic
categories for chronic anal pain: local causes, functional
anorectal pain, and neuropathic pain syndromes....
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Pool Toes: Case Report and Review of Pool-Associated Pedal Dermatoses
Pool swimmers are susceptible to pedal dermatoses. The causes for these conditions are asteototic dermatitis, contact dermatitis, friction-induced injury, infections, keratoderma, pruritus, thermal injury, ultraviolet radiation exposure, and urticaria. The specific dermatoses include aquagenic...
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Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
Background: Osteoporosis is an abnormal reduction in bone mass and bone deterioration leading to increased fracture risk. Risedronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts. This is an update of a Cochrane...
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