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Topical treatments for anal fissure

Author/s: Fagan, C., Kolber, M. R., Lindblad, A. J.

Clinical question
How effective are topical treatments (calcium channel blockers [CCBs], nitrates, and vitamin E) for
chronic anal fissures in adults?
Bottom line
Healing rates with topical nitroglycerin are roughly
60% versus 40% with placebo at 8 weeks. Topical...

Keywords/Tags:
Treatment Outcome vasodilator agents / therapeutic use nitroglycerin vasodilator agents anal fissure

Parkinson disease primer, part 1: diagnosis

Author/s: Frank, C., Chiu, R., Lee, J.

Objective To provide family physicians an updated approach to the diagnosis of Parkinson disease (PD).

Sources of information Published guidelines on the diagnosis and management of PD were reviewed. Database searches were conducted to retrieve relevant research articles published between...

Keywords/Tags:
Levodopa Parkinson's Disease diagnosis Parkinson Humans

Normal pressure hydrocephalus treated with ventriculoperitoneal shunt

Author/s: Fereshtehnejad, S., Nicholls, M., Huang, S., Akter, R.

Normal pressure hydrocephalus is a form of adult hydrocephalus with ventriculomegaly in the absence of any structural blockage of the cerebrospinal fluid circulation.

Normal pressure hydrocephalus is a partially reversible cause of dementia, manifesting with a triad of cognitive...

Keywords/Tags:
Hydrocephalus normal pressure neurology brain imaging ventriculoperitoneal shunt

Garlic lowers blood pressure in hypertensive subjects, improves arterial stiffness and gut microbiota: A review and meta-analysis

Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and...

Keywords/Tags:
aged garlic extract blood pressure hyptertension arterial stiffness gut microbiome

Air Quality Index and Childhood Asthma: A Pilot Randomized Clinical Trial Intervention

Author/s: Rosser, F. J., Rothenberger, S. D., Han, Y., Forno, E., Celedón, J. C.

Introduction: To reduce air pollution exposure, the U.S. asthma guidelines recommend that children check the Air Quality Index before outdoor activity. Whether adding the Air Quality Index and recommendations to asthma action plans reduces exacerbations and improves control and quality of life...

Keywords/Tags:
children quality of life asthma air pollution United States

Positional Plagiocephaly and Craniosynostosis

Author/s: Santiago, G. S., Santiage, C. N., Chwa, E. S., Purnell, C. A.

Along with the decrease in sudden infant death syndrome due to the successful "Back to Sleep" Campaign, there was a reciprocal increase in cases of positional plagiocephaly (PP). The prevalence of PP significantly rose from approximately 5% to upward of 46% at age 7 months. Consequently,...

Keywords/Tags:
infant sleep risk factors prevalence craniosynotoses plagiocephaly

Autism Spectrum Disorder: A Review

Author/s: Hirota, T., King, B. H.

Importance: Autism spectrum disorder (ASD), characterized by deficits in social communication and the presence of restricted, repetitive behaviors or interests, is a neurodevelopmental disorder affecting approximately 2.3% children aged 8 years in the US and approximately 2.2% of adults. This...

Keywords/Tags:
Autism Spectrum Disorder* / epidemiology irritable mood central nervous system stimulants autism ADHD

A Review on Lumps, Bumps, and Birthmarks: When and Why to Refer

Author/s: Brown, K. W., Lucas, E., Hoppe, I. C., Humphries, L. S.

Skin lesions of the face, trunk, and extremities are commonly seen in the pediatric population. Although most of these lesions are benign, they can be locally destructive or interfere with normal development. Recognition and diagnosis of these lesions allow for timely workup and referral;...

Keywords/Tags:
skin diseases pediatric diagnosis birthmarks assessment

Practical Management of Lumps and Bumps of the Fingers, Hand, and Wrist

Author/s: Ho Gung, J., Mehrzad, R., Bhatt, R. A.

Background: Primary care physicians encounter many patients who present with lumps and bumps on their fingers, hands, and wrists. Some benign lesions including ganglion cysts, epidermal inclusion cysts, and giant cell tumors of the tendon sheath that are benign and can be managed by primary care...

Keywords/Tags:
Dupuytren’s Contracture Epidermal Inclusion Cysts Fingers, Ganglion Cysts Giant Cell Tumors plastic surgery primary health care

The American Society of Pain and Neuroscience (ASPN) Evidence-Based Clinical Guideline of Interventional Treatments for Low Back Pain

Author/s: Sayed, D., Grider, J., Strand, N., Hagedorn, J. M., Falowski, S., Lam, C. M., Francio, V. T., Beall, D. P., Tomycz, N. D., Davanzo, J. R., Aiyer, R., Lee, D. W., Kaila, H., Sheen, S., Malinowski, M. N., Verdolin, M., Vodapally, S., Carayannopoulos, A., Jain, S., Azeem, N., Tolba, R., Chien, G. C. C., Ghosh, P., Mazzola, A. J., Amirdelfan, K., Chakravarthy, K., Petersen, E., Schatman, M. E., Deer, T.

Introduction
Painful lumbar spinal disorders represent a leading cause of disability in the US and worldwide. Interventional treatments for lumbar disorders are an effective treatment for the pain and disability from low back pain. Although many established and emerging interventional...

Keywords/Tags:
evidence-based interventional treatments Low Back Pain lumbar spinal disorders Pain

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