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Fixed drug eruption

Author/s: Chou, Yu-Ju, Chang, Hua-Ching

A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot.
Keywords/Tags:
drug eruptions asymptomatic erythematous doxycycline

Occupational hypersensitivity pneumonitis after polyurethane adhesive exposure

Author/s: Arbaaz, Hasany, Aasim, Tarlo, Susan M.

Key points
• Hypersensitivity pneumonitis is a type of interstitial lung
disease that requires early diagnosis and treatment as it may
lead to progressive pulmonary fibrosis.
• An occupational history is essential when evaluating patients
with respiratory symptoms....

Keywords/Tags:
adhesives Polyurethanes pneumonitis Hypersensitivity Pneumonitis

Therapy for Mild to Moderate Asthma

Author/s: Gray, S. E., Cife, A. S., Press, V. G.

GUIDELINE TITLE Global Strategy for Asthma Management
and Prevention (GINA Strategy Report)
RELEASE DATE April 26, 2021
PRIOR VERSION April 3, 2020
DEVELOPER AND FUNDING SOURCE The Global Initiative for
Asthma (GINA)
TARGET POPULATION Patients aged 12 y with...

Keywords/Tags:
asthma Mild to Moderate Asthma therapy recommendations Asthma Therapy

Effect of Physical Therapy vs Arthroscopic Partial Meniscectomy in People With Degenerative Meniscal Tears: Five-Year Follow-up of the ESCAPE Randomized Clinical Trial

Author/s: Noorduyn, J. C. A., Van de Graaf, V. A., Willigenburg, N. W., Scholten-Peeters, G. G. M., Kret, Kret, E. J., Van Dijk, R. A., Buchbinder, R., Hawker, G. A., Coppieters, M. W., Poolman, R. W., ESCAPE Research Group

Importance: There is a paucity of high-quality evidence about the long-term effects (ie, 3-5 years and beyond) of arthroscopic partial meniscectomy vs exercise-based physical therapy for patients with degenerative meniscal tears.

Objectives: To compare the 5-year effectiveness of...

Keywords/Tags:
Knee Injuries Follow-Up Studies randomized controlled trial Meniscus Injuries Meniscectomy

The Effectiveness of Intraosseous Basivertebral Nerve Radiofrequency Ablation for the Treatment of Vertebrogenic Low Back Pain: An Updated Systematic Review with Single-Arm Meta-analysis

Author/s: Conger, A., Burnham, T. R., Clark, T., Teramoto, M, McCormick, Z. L.

Objective. To provide an estimate of the effectiveness of basivertebral nerve (BVN) radiofrequency ablation (RFA) to
treat vertebrogenic low back pain (LBP). Design. Systematic review with single-arm meta-analysis. Population.
Persons 18 years of age with chronic LBP associated with...

Keywords/Tags:
Endplate Vertebrogenic Discogenic Modic Ablation

Women’s health update: A literature review impacting primary care

Author/s: Dolan, B. M., Merriam, S., Prifti, C. A., Walsh, J. M.

The authors review studies on key issues in women’s health with potential impact on internal medicine practice. The reviewed articles discuss cardiovascular disease risks, bone health, breast cancer genetics, cervical cancer prevention, depression in the peripartum period, pelvic pain, and...

Keywords/Tags:
Women's Health primary care Literature Review Internal Medicine Practice Disease Risks

Effect of Physical Therapy vs Arthroscopic Partial Meniscectomy in People With Degenerative Meniscal Tears: Five-Year Follow-up of the ESCAPE Randomized Clinical Trial

Author/s: Noordyun, J. C. A., Van de Graaf, V. A., Willigenburg, N. W., Scholten-Peeters, G. G. M., Kret, E. J., Van Dijk, R. A., Buchbinder, R., Hawker, G. A., Coppieters, M. W., Poolman, R. W., ESCAPE Research Group

Importance: There is a paucity of high-quality evidence about the long-term effects (ie, 3-5 years and beyond) of arthroscopic partial meniscectomy vs exercise-based physical therapy for patients with degenerative meniscal tears.

Objectives: To compare the 5-year effectiveness of...

Keywords/Tags:
physical therapy Arthroscopic Partial Meniscectomy clinical trial Knee osteoarthritis Degenerative Meniscal Tear

Gabapentin Increasingly Implicated in Overdose Deaths

Author/s: Kuehn, B. M.

Gabapentin Increasingly Implicated
in Overdose Deaths
Postmortem toxicology tests detected gabapentin in almost 1 in 10 US overdose deaths
between 2019 and 2020.In about half of the
cases, a medical examiner or coroner ruled
the drug was a cause of the death,...

Keywords/Tags:
gabapentin Insurance Benefits Off-Label Use Drug Overdose

Effect of Varenicline Added to Counseling on Smoking Cessation Among African American Daily Smokers The Kick It at Swope IV Randomized Clinical Trial

Author/s: Cox, L. S., Nollen, N. L., Mayo, M. S., Faseru, B., Greiner, A., Ellerbeck, E. F., Krebill, R., Tyndale, R. F., Benowitz, N. L., Ahluwalia, J. S.

Importance: African American smokers have among the highest rates of tobacco-attributable morbidity and mortality in the US, and effective treatment is needed for all smoking levels.

Objectives: To evaluate the efficacy of varenicline vs placebo among African American adults who are light...

Keywords/Tags:
Varenicline smoking African Americans Smokers clinical trial

Cannabis-Based Products for Chronic Pain : A Systematic Review

Author/s: McDonah, M. S., Morasco, B. J., Wagner, J., Ahmed, A. Y., Fu, R., Kansagara, D., Chou, R.

Background: Contemporary data are needed about the utility of cannabinoids in chronic pain.

Purpose: To evaluate the benefits and harms of cannabinoids for chronic pain.

Data sources: Ovid MEDLINE, PsycINFO, EMBASE, the Cochrane Library, and Scopus to January 2022.

Study...

Keywords/Tags:
Adverse events cannabinoids cannabis neuropathic pain Systematic reviews

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