Importance: Menopause, due to loss of ovarian follicular activity without another pathological or physiological cause, typically occurs between the ages of 45 years and 56 years. During the menopausal transition, approximately 50% to 75% of women have hot flashes, night sweats, or both (...
Library & Search Results
Diagnosis and acute management of migraine
Migraine is a leading cause of disability across all age groups.
• Routine imaging is not recommended in patients with migraine
who have no red flags, atypical symptoms or abnormal findings
on neurologic examination.
• A stratified approach for acute migraine treatment...
Transient ischemic attack and minor stroke: diagnosis, risk stratification and management
Patients with suspected cerebral ischemia should be urgently assessed to distinguish between transient ischemic attack (TIA), minor stroke or mimics such as migraine, seizure, vertigo or syncope.
The Canadian TIA Score can be used to determine risk for early subsequent stroke in patients...
Topical treatments for anal fissure
Clinical question
How effective are topical treatments (calcium channel blockers [CCBs], nitrates, and vitamin E) for
chronic anal fissures in adults?
Bottom line
Healing rates with topical nitroglycerin are roughly
60% versus 40% with placebo at 8 weeks. Topical...
Parkinson disease primer, part 1: diagnosis
Objective To provide family physicians an updated approach to the diagnosis of Parkinson disease (PD).
Sources of information Published guidelines on the diagnosis and management of PD were reviewed. Database searches were conducted to retrieve relevant research articles published between...
Normal pressure hydrocephalus treated with ventriculoperitoneal shunt
Normal pressure hydrocephalus is a form of adult hydrocephalus with ventriculomegaly in the absence of any structural blockage of the cerebrospinal fluid circulation.
Normal pressure hydrocephalus is a partially reversible cause of dementia, manifesting with a triad of cognitive...
Garlic lowers blood pressure in hypertensive subjects, improves arterial stiffness and gut microbiota: A review and meta-analysis
Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and...
Air Quality Index and Childhood Asthma: A Pilot Randomized Clinical Trial Intervention
Introduction: To reduce air pollution exposure, the U.S. asthma guidelines recommend that children check the Air Quality Index before outdoor activity. Whether adding the Air Quality Index and recommendations to asthma action plans reduces exacerbations and improves control and quality of life...
Positional Plagiocephaly and Craniosynostosis
Along with the decrease in sudden infant death syndrome due to the successful "Back to Sleep" Campaign, there was a reciprocal increase in cases of positional plagiocephaly (PP). The prevalence of PP significantly rose from approximately 5% to upward of 46% at age 7 months. Consequently,...
Autism Spectrum Disorder: A Review
Importance: Autism spectrum disorder (ASD), characterized by deficits in social communication and the presence of restricted, repetitive behaviors or interests, is a neurodevelopmental disorder affecting approximately 2.3% children aged 8 years in the US and approximately 2.2% of adults. This...