1. Home
  2. Search by Resource
  3. Article
  4. Poster
  5. Search for Resource

Library & Search Results

Diagnosis and Treatment of Myelodysplastic Syndromes: A Review

Author/s: Sekeres, M. A., Taylor, J.

Importance Myelodysplastic neoplasms (MDS), formerly known as myelodysplastic syndromes, are clonal hematopoietic malignancies that cause morphologic bone marrow dysplasia along with anemia, neutropenia, or thrombocytopenia. MDS are associated with an increased risk of acute myeloid leukemia (...

Keywords/Tags:
Leukemia Hematinics Prognosis Myedysplastic syndromes drug therapy

Pre-exposure prophylaxis for HIV: effective and underused

Author/s: Hempel, A., Biondi, M. J., Baril, J., Tan, D. H. S.

Pre-exposure prophylaxis (PrEP) is a highly effective modality for HIV prevention that can be prescribed by generalists.

Pre-exposure prophylaxis should be offered to patients who are at high risk of HIV exposure, including gay, bisexual and other men who have sex with men (GBM), women...

Keywords/Tags:
Follow-Up Studies Substance Abuse, intravenous Canada sexually transmitted diseases Drug users

Management of acute diverticulitis

Author/s: Zondervan, N., Snelgrove, R., Bradley, N.

1 Emergency department visits and hospital admissions for acute
diverticulitis have increased
Emergency department visits for acute diverticulitis increased by 26.8% to
113.9 visits per 100 000 from 2006 to 2013 in the United States.1
Hospital admissions for...

Keywords/Tags:
Colonoscopy abscess Anti-Bacterial Agents Bacterial translocation sepsis

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

Author/s: Humbert, M., Kovacs, G., Hoeper, M. M., Badagliacca, R., Berger, R. M. F., Brida, M., Carlsen, J., Coats, A. J. S., Escribano-Subias, P., Ferrari, P., Ferreira, D. S., Ghofrani, H. A., Ginnakoulas, G., Kiely, D. G., Mayer, E., Meszaros, G., Nagavci, B., Olsson, K. M., Pepke-Zaba, J., Quint, J. K., Rådegran, G., Simonneau, G., Sitbon, O., Tonia, T., Toshner, M., Vachiery, J. L., Noordegraaf, A. V., Delcroix, M., Rosenkranz, S., ESC/ERS Scientific Document Group

Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple clinical conditions and may be associated with a variety of cardiovascular and respiratory diseases. The complexity of managing PH requires a multifaceted, holistic, and multidisciplinary approach, with active...

Keywords/Tags:
Chronic Thrombo-embolic pulmonary hypertension clinical practice cardiovascular respiratory disease Pathophysiological disorder

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

Author/s: Humbert, M., Kovacs, G., Hoeper, M. M., Badagliacca, R., Berger, R. M. F., Brida, M., Carlsen, J., Coats, A. J. S., Escribano-Subias, P., Ferrari, P., Ferreira, D. S., Ghofrani, H. A., Ginnakoulas, G., Kiely, D. G., Mayer, E., Meszaros, G., Nagavci, B., Olsson, K. M., Pepke-Zaba, J., Quint, J. K., Rådegran, G., Simonneau, G., Sitbon, O., Tonia, T., Toshner, M., Vachiery, J. L., Noordegraaf, A. V., Delcroix, M., Rosenkranz, S., ESC/ERS Scientific Document Group

Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple clinical conditions and may be associated with a variety of cardiovascular and respiratory diseases. The complexity of managing PH requires a multifaceted, holistic, and multidisciplinary approach, with active...

Keywords/Tags:
Chronic Thrombo-embolic pulmonary hypertension clinical practice cardiovascular respiratory disease Pathophysiological disorder

Optimal Urine Culture Diagnostic Stewardship Practice-Results from an Expert Modified-Delphi Procedure

Author/s: Claeys, K. C., Trautner, B. W., Leekha, S., Coffey, K. C., Crnich, C. J., Diekema, D. J., Fakih, M. G., Goetz, M. B., Gupta, K., Jones, M. M., Leykum, L., Liang, S. Y., Pineles, L., Pleiss, A., Spivak, E. S., Suda, K. J., Taylor, J. M., Rhee, C., Morgan, D. J.

Background: Urine cultures are nonspecific and often lead to misdiagnosis of urinary tract infection and unnecessary antibiotics. Diagnostic stewardship is a set of procedures that modifies test ordering, processing, and reporting in order to optimize diagnosis and downstream treatment. In this...

Keywords/Tags:
Diagnostic Stewardship Expert consensus modified Delphi urinary tract infections urine cultures

Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis

Author/s: Yin, X., Rodgers, A., Perkovic, A., Huang, L., Li, K., Yu, J., Wu, Y., Wu, J. H. Y., Marklund, M., Huffman, M. D., Miranda, J. J., Di Tanna, G. L., Labarthe, D., Elliott, P., Tian, M., Neal, B.

Objectives The Salt Substitute and Stroke Study (SSaSS) recently reported blood pressure-mediated benefits of a potassium-enriched salt substitute on cardiovascular outcomes and death. This study assessed the effects of salt substitutes on a breadth of outcomes to quantify the consistency of the...

Keywords/Tags:
hypertension meta-analysis stroke Salt Substitutes blood pressure

International normalized ratio and activated partial thromboplastin time testing

Author/s: Chornenki, N. L. J., Fralick, M., Sholzberg, M.

International normalized ratio (INR) and activated partial thromboplastin time (aPTT) have limited clinical utility
The INR and aPTT should be used only for specific clinical indications (see Appendix 1, available at...

Keywords/Tags:
Bleeding disorder direct oral anticoagulants activated partial thromboplastin International normalized ratio Specimen handling

Covid-19 Vaccines — Immunity, Variants, Boosters

Author/s: Barouch, D. H.

The coronavirus disease 2019 (Covid-19) pandemic has claimed an estimated 15 million lives, including more than 1 million lives in the United States alone. The rapid development of multiple Covid-19 vaccines has been a triumph of biomedical research, and billions of vaccine doses have been...

Keywords/Tags:
United States Biomedical Research vaccines Pandemics Immunity

Treatment of Clostridioides difficile Infection

Author/s: Sehgal, K., Cifu, A. S., Khanna, S.

GUIDELINE TITLE ACG Clinical Guidelines: Prevention,
Diagnosis, and Treatment of Clostridioides difficile Infections
RELEASE DATE May 18, 2021
PRIOR VERSION 2013
DEVELOPER American College of Gastroenterology (ACG)
FUNDING SOURCE ACG
TARGET POPULATION Adults...

RPR User Guide

Research-to-Practice-to-Research (RPR) Exchange

If you need assistance with the RPR Exchange, please use the QOS form and leave a question or suggestion.  We review them regularly and will get back with you.  If you  need general information about using the RPR Exchange, the User Guide is available on-line.  You might also find the FAQs useful for some of the common questions RPR users have.