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https://www.rpr.lib.ok.us/taxonomy/term/8990/all
enCost-effectiveness of management strategies in recurrent acute otitis media
https://www.rpr.lib.ok.us/resource/cost-effectiveness-management-strategies-recurrent-acute-otitis-media
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
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<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2022-12-11T00:00:00-06:00">December 11, 2022</span></div>
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<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
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<div class="field-item even">The Journal of Pediatrics</div>
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<div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix">
<div class="field-label">Publisher: </div>
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<div class="field-item even">Elsevier</div>
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<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
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<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2022-12-03T00:00:00-06:00">December 3, 2022</span></div>
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<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
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<div class="field-item even"><a href="https://www.jpeds.com/article/S0022-3476(22)01092-7/fulltext?dgcid=raven_jbs_aip_email" target="_blank">Cost-effectiveness of management strategies in recurrent acute otitis media</a></div>
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<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
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<div class="field-item even">Clinical Research Results</div>
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<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
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<div class="field-item even">Article</div>
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<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
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<div class="field-item even">10.1016/j.jpeds.2022.11.032</div>
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<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
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<div class="field-item even"><a href="/tags/recurrent-acute-otitis-media" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Recurrent acute otitis media</a></div>
<div class="field-item odd"><a href="/tags/ear-infections" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">ear infections</a></div>
<div class="field-item even"><a href="/tags/tympanostomy-tube-placement" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Tympanostomy tube placement</a></div>
<div class="field-item odd"><a href="/tags/nonsurgical-medical-management" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">nonsurgical medical management</a></div>
<div class="field-item even"><a href="/tags/acute-otitis-media" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">acute otitis media</a></div>
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<div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix">
<div class="field-label">PMID (1): </div>
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<div class="field-item even">36470464</div>
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<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/drug-resistance-microbial" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Drug Resistance, Microbial</a></div>
<div class="field-item odd"><a href="/mesh/treatment-failure" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Treatment Failure</a></div>
<div class="field-item even"><a href="/mesh/anti-bacterial-agents" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">anti-bacterial agents</a></div>
<div class="field-item odd"><a href="/mesh/quality-life" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">quality of life</a></div>
<div class="field-item even"><a href="/mesh/otitis-media" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Otitis Media</a></div>
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<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
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<div class="field-item even"><p>In children with recurrent acute otitis media, medical management is preferred over tympanostomy tubes from a cost-effectiveness perspective. James W. Mold, MD, MPH</p>
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<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
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<div class="field-item even">Free full text</div>
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<a href="https://www.jpeds.com/article/S0022-3476(22)01092-7/fulltext?dgcid=raven_jbs_aip_email" class="btn btn-primary" target="_blank">View</a> </div>
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<div class="field-item even" property="content:encoded"><p>Objective: To evaluate the cost-effectiveness of tympanostomy tube placement vs. nonsurgical medical management, with the option of tympanostomy tube placement in the event of treatment failure, in children with recurrent acute otitis media (AOM).</p>
<p>Study design: A Markov decision model compared management strategies in children ages 6 to 35 months, using patient-level data from a recently completed, multicenter, randomized clinical trial of tympanostomy tube placement vs. medical management. The model ran over a two-year time horizon using a societal perspective. Probabilities, including risk of AOM symptoms, were derived from prospectively collected patient diaries. Costs and quality-of-life measures were derived from the literature. We performed one-way and probabilistic sensitivity analyses, and secondary analyses in predetermined low- and high-risk subgroups. The primary outcome was incremental cost per quality-adjusted life-year gained.</p>
<p>Results: Tympanostomy tubes cost $989 more per child than medical management. Children managed with tympanostomy tubes gained 0.69 more quality-adjusted life-days than children managed medically, corresponding to $520,855 per quality-adjusted life-year gained. Results were sensitive to the costs of oral antibiotics, missed work, special childcare, the societal cost of antibiotic resistance, and the quality of life associated with AOM. In probabilistic sensitivity analyses, medical management was favored in 66% of model iterations at a willingness-to-pay threshold of $100,000/quality-adjusted life-year. Medical management was preferred in secondary analyses of low- and high-risk subgroups.</p>
<p>Conclusions: For young children with recurrent AOM, the additional cost associated with tympanostomy tube placement outweighs the small improvement in quality of life. Medical management for these children is an economically reasonable strategy.</p>
<p>Keywords: acute otitis media; economic analysis; tympanostomy tubes.</p>
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<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
<div class="field-items">
<div class="field-item even">Noorbakhsh, K. A., Liu, H., Kurs-Lasky, M., Smith, K. J., Hoberman, A., Shakh, N.</div>
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Sun, 11 Dec 2022 06:00:00 +0000Aubrey Delammermore1943 at https://www.rpr.lib.ok.us