Practice Guidelines as Topic / standards*

Topical Therapies for Atopic Dermatitis

Rowan Hutchins — Sun, 12 Nov 2023 21:20:37 +0000

Date Added:

November 12, 2023

Journal/Publication:

JAMA

Publisher:

AMA

Publication Date:

October 27, 2023

URL:

Topical Therapies for Atopic Dermatitis

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

DOI (1):

10.1001/jama.2023.17719

Keywords

Atopic Dermatitis

guidelines

allergy and clinical immunology

PMID (1):

37889498

MeSH

Dermatitis, Atopic

dermatology

Practice Guidelines as Topic / standards*

clinical decision-making

A summary of current topical treatment options for atopic dermatitis. James W. Mold, MD, MPH

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Atopic dermatitis (AD) is a chronic inflammatory skin condition affecting approximately 10% of the US population. AD often occurs as a childhood disease in conjunction with allergies and asthma, but it can also persist into or arise de novo in adulthood. AD negatively affects quality of life, social interactions, and work productivity, with annual US health care costs exceeding $5.3 billion.1 The current guideline provides recommendations on the management of AD in adults with both nonpharmacologic and pharmacologic topical therapies

Author/s:

Amy Z. Xu, Jason T. Alexander

Canadian guideline for the clinical management of high-risk drinking and alcohol use disorder

Rowan Hutchins — Sun, 22 Oct 2023 05:00:00 +0000

Date Added:

October 22, 2023

Journal/Publication:

CMAJ

Publisher:

CMA

Publication Date:

October 16, 2023

Issue:

Volume:

195

Pages:

E1364-E1379

URL:

Canadian guideline for the clinical management of high-risk drinking and alcohol use disorder

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

DOI (1):

10.1503/cmaj.230715

Keywords

alcohol

alcohol abuse

PMID (1):

37844924

MeSH

Alcohol use disorder

Practice Guidelines as Topic / standards*

Canadian Guidelines for management of alcohol use disorder. James W. Mold, MD, MPH

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Background: In Canada, low awareness of evidence-based interventions for the clinical management of alcohol use disorder exists among health care providers and people who could benefit from care. To address this gap, the Canadian Research Initiative in Substance Misuse convened a national committee to develop a guideline for the clinical management of high-risk drinking and alcohol use disorder.

Methods: Development of this guideline followed the ADAPTE process, building upon the 2019 British Columbia provincial guideline for alcohol use disorder. A national guideline committee (consisting of 36 members with diverse expertise, including academics, clinicians, people with lived and living experiences of alcohol use, and people who self-identified as Indigenous or Métis) selected priority topics, reviewed evidence and reached consensus on the recommendations. We used the Appraisal of Guidelines for Research and Evaluation Instrument (AGREE II) and the Guidelines International Network’s Principles for Disclosure of Interests and Management of Conflicts to ensure the guideline met international standards for transparency, high quality and methodological rigour. We rated the final recommendations using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) tool; the recommendations underwent external review by 13 national and international experts and stakeholders.

Recommendations: The guideline includes 15 recommendations that cover screening, diagnosis, withdrawal management and ongoing treatment, including psychosocial treatment interventions, pharmacotherapies and community-based programs. The guideline committee identified a need to emphasize both underused interventions that may be beneficial and common prescribing and other practice patterns that are not evidence based and that may potentially worsen alcohol use outcomes.

Interpretation: The guideline is intended to be a resource for physicians, policymakers and other clinical and nonclinical personnel, as well as individuals, families and communities affected by alcohol use. The recommendations seek to provide a framework for addressing a large burden of unmet treatment and care needs for alcohol use disorder within Canada in an evidence-based manner.

Author/s:

Evan Wood, Jessica Bright, Katrina Hsu, Nirupa Goel, Josey W.G. Ross, Averill Hanson, Rand Teed, Ginette Poulin, Bryany Denning, Kim Corace, Corrina Chase, Katelyn Halpape, Ronald Lim, Tim Kealey, Jürgen Rehm

Health supervision for children with Down syndrome

Aubrey Delammermore — Sun, 06 Nov 2022 05:00:00 +0000

Date Added:

November 6, 2022

Journal/Publication:

American Academy of Pediatrics

Publisher:

American Academy of Pediatrics

Publication Date:

August 1, 2011

Issue:

Volume:

182

Pages:

393-406

URL:

Health supervision for children with Down syndrome

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

DOI (1):

10.1542/peds.2011-1605

Keywords

Academies and Institutes / standards*

Age Factors

Pediatrics / methods

Pediatrics / standards*

Genetic Counseling / standards

PMID (1):

21788214

MeSH

Down Syndrome / diagnosis*

Down Syndrome / therapy*

Practice Guidelines as Topic / standards*

Prenatal Diagnosis / methods

Prenatal Diagnosis / standards

Recommended guidelines for the routine care of children with Down’s Syndrome. James W. Mold, MD, MPH

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These guidelines are designed to assist the pediatrician in caring for the child in whom a diagnosis of Down syndrome has been confirmed by chromosome analysis. Although a pediatrician's initial contact with the child is usually during infancy, occasionally the pregnant woman who has been given a prenatal diagnosis of Down syndrome will be referred for review of the condition and the genetic counseling provided. Therefore, this report offers guidance for this situation as well.

Author/s:

Bull, M. J., Committee on Genetics