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https://www.rpr.lib.ok.us/taxonomy/term/8699/all en https://www.rpr.lib.ok.us/resource/effect-fluvoxamine-outcomes-nonhospitalized-patients-covid-19-systematic-review-and-meta <div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Date Added:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2022-11-06T00:00:00-05:00">November 6, 2022</span></div> </div> </div> <div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix"> <div class="field-label">Journal/Publication:&nbsp;</div> <div class="field-items"> <div class="field-item even">Journal of Infection and Public Health</div> </div> </div> <div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix"> <div class="field-label">Publisher:&nbsp;</div> <div class="field-items"> <div class="field-item even">Elsevier B. V.</div> </div> </div> <div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Publication Date:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2022-10-13T00:00:00-05:00">October 13, 2022</span></div> </div> </div> <div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix"> <div class="field-label">Issue:&nbsp;</div> <div class="field-items"> <div class="field-item even">11</div> </div> </div> <div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix"> <div class="field-label">Volume:&nbsp;</div> <div class="field-items"> <div class="field-item even">15</div> </div> </div> <div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix"> <div class="field-label">Pages:&nbsp;</div> <div class="field-items"> <div class="field-item even">1259-1264</div> </div> </div> <div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix"> <div class="field-label">URL:&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="https://www.sciencedirect.com/science/article/pii/S1876034122002659?via%3Dihub" target="_blank">Effect of fluvoxamine on outcomes of nonhospitalized patients with COVID-19: A systematic review and meta-analysis</a></div> </div> </div> <div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Type:&nbsp;</div> <div class="field-items"> <div class="field-item even">Meta-analyses, Reviews, and Guidelines</div> </div> </div> <div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Format:&nbsp;</div> <div class="field-items"> <div class="field-item even">Article</div> </div> </div> <div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix"> <div class="field-label">DOI (1):&nbsp;</div> <div class="field-items"> <div class="field-item even">10.1016/j.jiph.2022.10.010</div> </div> </div> <div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above"> <div class="field-label">Keywords&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/tags/odds-ratio" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Odds Ratio</a></div> <div class="field-item odd"><a href="/tags/artificial-respiration" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Artificial respiration</a></div> <div class="field-item even"><a href="/tags/control-groups" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">control groups</a></div> <div class="field-item odd"><a href="/tags/hospitalization" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">hospitalization</a></div> <div class="field-item even"><a href="/tags/bibliometrics" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">bibliometrics</a></div> </div> </div> <div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix"> <div class="field-label">PMID (1):&nbsp;</div> <div class="field-items"> <div class="field-item even">36272390</div> </div> </div> <div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above"> <div class="field-label">MeSH&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/mesh/sars-cov-2" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">SARS-CoV-2</a></div> <div class="field-item odd"><a href="/mesh/covid-19" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">COVID-19</a></div> <div class="field-item even"><a href="/mesh/fluvoxamine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Fluvoxamine</a></div> <div class="field-item odd"><a href="/mesh/emergency-service" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Emergency Service</a></div> <div class="field-item even"><a href="/mesh/hospital" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Hospital</a></div> <div class="field-item odd"><a href="/mesh/intensive-care-units" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Intensive Care Units</a></div> </div> </div> <div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden"> <div class="field-items"> <div class="field-item even"><p>Fluvoxamine can reduce risk of hospitalization in outpatients with COVID-19. James W. Mold, MD, MPH</p> </div> </div> </div> <div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden"> <div class="field-items"> <div class="field-item even">Free full text</div> </div> </div> <div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden"> <div class="field-items"> <div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-282f19d9f3220157a719d74f3716dcf6"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <a href="https://www.sciencedirect.com/science/article/pii/S1876034122002659?via%253Dihub=" class="btn btn-primary" target="_blank">View</a> </div> </div> </div></div> </div> </div> <div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="content:encoded"><p>Objectives: This meta-analysis investigated the use of fluvoxamine for the treatment of nonhospitalized patients with COVID-19.</p> <p>Methods: PubMed, Web of Science, Ovid medline, Embase, Scopus, Cochrane Library databases, and ClinicalTrials.gov were searched for studies published before June 25, 2022. Only clinical studies that compared the efficacy and safety of fluvoxamine with other alternatives or placebos in the treatment of nonhospitalized patients with COVID-19 were included.</p> <p>Results: Four studies with 1814 patients, of whom 912 received fluvoxamine, were included in this study. Compared with the control group receiving placebo or no therapy, the study group receiving fluvoxamine demonstrated a lower risk of hospitalization and emergency department (ED) visits (odds ratio [OR], 0.59; 95 % CI, 0.44-0.79; I2 = 26 %). In addition, the rate of hospitalization remained significantly lower in patients who received fluvoxamine than in the control group (OR, 0.69; 95 % CI, 0.51-0.94; I2 = 36 %). Although the study group demonstrated a lower risk of requirement of mechanical ventilation and intensive care unit admission, and mortality than the control group, these differences were nonsignificant. Finally, fluvoxamine use was associated with a similar risk of adverse events as that observed in the control group.</p> <p>Conclusion: Fluvoxamine can be safely used in nonhospitalized patients with COVID-19 and can reduce the hospitalization rate or ED visits in these patients.</p> <p>Keywords: COVID-19; Emergency department; Fluvoxamine; Hospitalization; SARS-CoV-2.</p> </div> </div> </div> <div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Author/s:&nbsp;</div> <div class="field-items"> <div class="field-item even">Lu, L., Chao, C., Chang, S., Lan, S., Lai, C.</div> </div> </div> Sun, 06 Nov 2022 05:00:00 +0000 Aubrey Delammermore 1909 at https://www.rpr.lib.ok.us