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https://www.rpr.lib.ok.us/taxonomy/term/4256/all
en2024 edition of the Rourke Baby Record
https://www.rpr.lib.ok.us/resource/2024-edition-rourke-baby-record-0
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2025-09-13T00:00:00-05:00">September 13, 2025</span></div>
</div>
</div>
<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
<div class="field-items">
<div class="field-item even">Canadian Family Physician</div>
</div>
</div>
<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2025-09-13T00:00:00-05:00">September 13, 2025</span></div>
</div>
</div>
<div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix">
<div class="field-label">Issue: </div>
<div class="field-items">
<div class="field-item even">9</div>
</div>
</div>
<div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix">
<div class="field-label">Volume: </div>
<div class="field-items">
<div class="field-item even">71</div>
</div>
</div>
<div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix">
<div class="field-label">Pages: </div>
<div class="field-items">
<div class="field-item even"> 553-561</div>
</div>
</div>
<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
<div class="field-items">
<div class="field-item even"><a href="https://pubmed.ncbi.nlm.nih.gov/40940145/" target="_blank">2024 edition of the Rourke Baby Record</a></div>
</div>
</div>
<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
<div class="field-items">
<div class="field-item even">Meta-analyses, Reviews, and Guidelines</div>
</div>
</div>
<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
<div class="field-items">
<div class="field-item even">Article</div>
</div>
</div>
<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
<div class="field-items">
<div class="field-item even">10.46747/cfp.7109553</div>
</div>
</div>
<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
<div class="field-items">
<div class="field-item even"><a href="/tags/child" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">child</a></div>
<div class="field-item odd"><a href="/tags/infant" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">infant</a></div>
<div class="field-item even"><a href="/tags/baby" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Baby</a></div>
</div>
</div>
<div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix">
<div class="field-label">PMID (1): </div>
<div class="field-items">
<div class="field-item even">40940145</div>
</div>
</div>
<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/child" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">child</a></div>
<div class="field-item odd"><a href="/mesh/infant" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">infant</a></div>
<div class="field-item even"><a href="/mesh/preschool" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Preschool</a></div>
<div class="field-item odd"><a href="/mesh/literacy" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Literacy</a></div>
<div class="field-item even"><a href="/mesh/diet" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">diet</a></div>
<div class="field-item odd"><a href="/mesh/vegan" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vegan</a></div>
<div class="field-item even"><a href="/mesh/cannabis" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">cannabis</a></div>
<div class="field-item odd"><a href="/mesh/expert-testimony" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Expert Testimony</a></div>
<div class="field-item even"><a href="/mesh/singing" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Singing</a></div>
<div class="field-item odd"><a href="/mesh/hallucinogens" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Hallucinogens</a></div>
<div class="field-item even"><a href="/mesh/culturally-competent-care" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Culturally Competent Care</a></div>
<div class="field-item odd"><a href="/mesh/primary-health-care" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">primary health care</a></div>
<div class="field-item even"><a href="/mesh/vegetarians" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vegetarians</a></div>
<div class="field-item odd"><a href="/mesh/eating" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Eating</a></div>
</div>
</div>
<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
<div class="field-items">
<div class="field-item even"><p>This is an article explaining and updating a tool used in many Canadian practices that care for babies and their mothers. The actual Baby Record can b downloaded free at <a href="https://www.rourkebabyrecord.ca">https://www.rourkebabyrecord.ca</a></p>
</div>
</div>
</div>
<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
<div class="field-items">
<div class="field-item even">Free full text</div>
</div>
</div>
<div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden">
<div class="field-items">
<div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-e6eda46e25f7586f43c34bcb0c48036d">
<div class="view-content">
<div class="views-row views-row-1 views-row-odd views-row-first views-row-last">
<a href="https://pubmed.ncbi.nlm.nih.gov/40940145/" class="btn btn-primary" target="_blank">View</a> </div>
</div>
</div></div>
</div>
</div>
<div class="field field-name-body field-type-text-with-summary field-label-hidden">
<div class="field-items">
<div class="field-item even" property="content:encoded"><p>Objective: To assist busy primary care providers caring for infants and young children and their families by providing them with the most recent recommendations and supportive evidence included in the 2024 edition of the Rourke Baby Record (RBR).</p>
<p>Quality of evidence: Articles from pediatric preventive care literature (January 2019 to March 2023) were reviewed for relevance and quality of evidence. When available, evidence from systematic reviews, relevant clinical guidelines, and clinical trials were incorporated. In the absence of high-level evidence, observational studies and expert opinion on the topic were included. Primary research studies were reviewed and critically appraised using a modified protocol.</p>
<p>Main message: Notable updates in the 2024 edition of the RBR include the promotion of early relational health for families; identification of targeted support and resources as opposed to labelling of high-risk groups; guidance on culturally safe care; clarification and evidence-based adjustments of the age of achievement of some developmental surveillance milestones; recommendations on plant-based beverages, vegetarian, and vegan diets; screening considerations for iron deficiency; dangers of ingestion of button batteries and cannabis edibles; literacy and socioemotional benefits of reading, singing, and storytelling; the importance of unstructured outdoor play; the environment's effect on children's health; the significance of sentinel injuries; acholic stools; and the normal presence and abnormal persistence of developmental (primitive) reflexes.</p>
<p>Conclusion: Building on its 40-year history, the 2024 RBR provides freely available, evidence-informed recommendations to guide clinicians in providing effective, up-to-date, and comprehensive preventive pediatric care. Despite the challenging and evolving landscape of primary health care delivery, the RBR will continue to support primary care providers.</p>
</div>
</div>
</div>
<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
<div class="field-items">
<div class="field-item even">Anne Rowan-Legg, Patricia Li, Bruce Kwok, Leslie Rourke, Denis Leduc, James Rourke, Imaan Bayoumi</div>
</div>
</div>
Sat, 13 Sep 2025 19:21:41 +0000Hope Smashey2761 at https://www.rpr.lib.ok.us2024 edition of the Rourke Baby Record
https://www.rpr.lib.ok.us/resource/2024-edition-rourke-baby-record
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2025-09-13T00:00:00-05:00">September 13, 2025</span></div>
</div>
</div>
<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
<div class="field-items">
<div class="field-item even">Canadian Family Physician</div>
</div>
</div>
<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2025-09-13T00:00:00-05:00">September 13, 2025</span></div>
</div>
</div>
<div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix">
<div class="field-label">Issue: </div>
<div class="field-items">
<div class="field-item even">9</div>
</div>
</div>
<div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix">
<div class="field-label">Volume: </div>
<div class="field-items">
<div class="field-item even">71</div>
</div>
</div>
<div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix">
<div class="field-label">Pages: </div>
<div class="field-items">
<div class="field-item even"> 553-561</div>
</div>
</div>
<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
<div class="field-items">
<div class="field-item even"><a href="https://pubmed.ncbi.nlm.nih.gov/40940145/" target="_blank">2024 edition of the Rourke Baby Record</a></div>
</div>
</div>
<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
<div class="field-items">
<div class="field-item even">Meta-analyses, Reviews, and Guidelines</div>
</div>
</div>
<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
<div class="field-items">
<div class="field-item even">Article</div>
</div>
</div>
<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
<div class="field-items">
<div class="field-item even">10.46747/cfp.7109553</div>
</div>
</div>
<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
<div class="field-items">
<div class="field-item even"><a href="/tags/child" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">child</a></div>
<div class="field-item odd"><a href="/tags/infant" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">infant</a></div>
<div class="field-item even"><a href="/tags/baby" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Baby</a></div>
</div>
</div>
<div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix">
<div class="field-label">PMID (1): </div>
<div class="field-items">
<div class="field-item even">40940145</div>
</div>
</div>
<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/child" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">child</a></div>
<div class="field-item odd"><a href="/mesh/infant" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">infant</a></div>
<div class="field-item even"><a href="/mesh/preschool" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Preschool</a></div>
<div class="field-item odd"><a href="/mesh/literacy" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Literacy</a></div>
<div class="field-item even"><a href="/mesh/diet" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">diet</a></div>
<div class="field-item odd"><a href="/mesh/vegan" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vegan</a></div>
<div class="field-item even"><a href="/mesh/cannabis" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">cannabis</a></div>
<div class="field-item odd"><a href="/mesh/expert-testimony" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Expert Testimony</a></div>
<div class="field-item even"><a href="/mesh/singing" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Singing</a></div>
<div class="field-item odd"><a href="/mesh/hallucinogens" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Hallucinogens</a></div>
<div class="field-item even"><a href="/mesh/culturally-competent-care" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Culturally Competent Care</a></div>
<div class="field-item odd"><a href="/mesh/primary-health-care" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">primary health care</a></div>
<div class="field-item even"><a href="/mesh/vegetarians" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vegetarians</a></div>
<div class="field-item odd"><a href="/mesh/eating" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Eating</a></div>
</div>
</div>
<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
<div class="field-items">
<div class="field-item even"><p>This is an article explaining and updating a tool used in many Canadian practices that care for babies and their mothers. The actual Baby Record can b downloaded free at <a href="https://www.rourkebabyrecord.ca">https://www.rourkebabyrecord.ca</a></p>
</div>
</div>
</div>
<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
<div class="field-items">
<div class="field-item even">Free full text</div>
</div>
</div>
<div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden">
<div class="field-items">
<div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-1e958508520acfc258b9d7edccb832c4">
<div class="view-content">
<div class="views-row views-row-1 views-row-odd views-row-first views-row-last">
<a href="https://pubmed.ncbi.nlm.nih.gov/40940145/" class="btn btn-primary" target="_blank">View</a> </div>
</div>
</div></div>
</div>
</div>
<div class="field field-name-body field-type-text-with-summary field-label-hidden">
<div class="field-items">
<div class="field-item even" property="content:encoded"><p>Objective: To assist busy primary care providers caring for infants and young children and their families by providing them with the most recent recommendations and supportive evidence included in the 2024 edition of the Rourke Baby Record (RBR).</p>
<p>Quality of evidence: Articles from pediatric preventive care literature (January 2019 to March 2023) were reviewed for relevance and quality of evidence. When available, evidence from systematic reviews, relevant clinical guidelines, and clinical trials were incorporated. In the absence of high-level evidence, observational studies and expert opinion on the topic were included. Primary research studies were reviewed and critically appraised using a modified protocol.</p>
<p>Main message: Notable updates in the 2024 edition of the RBR include the promotion of early relational health for families; identification of targeted support and resources as opposed to labelling of high-risk groups; guidance on culturally safe care; clarification and evidence-based adjustments of the age of achievement of some developmental surveillance milestones; recommendations on plant-based beverages, vegetarian, and vegan diets; screening considerations for iron deficiency; dangers of ingestion of button batteries and cannabis edibles; literacy and socioemotional benefits of reading, singing, and storytelling; the importance of unstructured outdoor play; the environment's effect on children's health; the significance of sentinel injuries; acholic stools; and the normal presence and abnormal persistence of developmental (primitive) reflexes.</p>
<p>Conclusion: Building on its 40-year history, the 2024 RBR provides freely available, evidence-informed recommendations to guide clinicians in providing effective, up-to-date, and comprehensive preventive pediatric care. Despite the challenging and evolving landscape of primary health care delivery, the RBR will continue to support primary care providers.</p>
</div>
</div>
</div>
<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
<div class="field-items">
<div class="field-item even">Anne Rowan-Legg, Patricia Li, Bruce Kwok, Leslie Rourke, Denis Leduc, James Rourke, Imaan Bayoumi</div>
</div>
</div>
Sat, 13 Sep 2025 19:21:20 +0000Hope Smashey2759 at https://www.rpr.lib.ok.usAcid Suppression and Antibiotics Administered During Infancy Are Associated with Celiac Disease
https://www.rpr.lib.ok.us/resource/acid-suppression-and-antibiotics-administered-during-infancy-are-associated-celiac-disease
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2022-10-22T00:00:00-05:00">October 22, 2022</span></div>
</div>
</div>
<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
<div class="field-items">
<div class="field-item even">The Journal of Pediatrics</div>
</div>
</div>
<div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix">
<div class="field-label">Publisher: </div>
<div class="field-items">
<div class="field-item even">Elsevier</div>
</div>
</div>
<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2022-10-17T00:00:00-05:00">October 17, 2022</span></div>
</div>
</div>
<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
<div class="field-items">
<div class="field-item even"><a href="https://www.jpeds.com/article/S0022-3476(22)00900-3/fulltext?dgcid=raven_jbs_aip_email#relatedArticles" target="_blank">Acid Suppression and Antibiotics Administered During Infancy Are Associated with Celiac Disease</a></div>
</div>
</div>
<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
<div class="field-items">
<div class="field-item even">Clinical Research Results</div>
</div>
</div>
<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
<div class="field-items">
<div class="field-item even">Article</div>
</div>
</div>
<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
<div class="field-items">
<div class="field-item even">10.1016/j.jpeds.2022.10.013</div>
</div>
</div>
<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
<div class="field-items">
<div class="field-item even"><a href="/tags/infancy" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Infancy</a></div>
<div class="field-item odd"><a href="/tags/retrospective-studies" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Retrospective Studies</a></div>
<div class="field-item even"><a href="/tags/children" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">children</a></div>
<div class="field-item odd"><a href="/tags/prescriptions" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">prescriptions</a></div>
<div class="field-item even"><a href="/tags/celiac-disease" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">celiac disease</a></div>
</div>
</div>
<div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix">
<div class="field-label">PMID (1): </div>
<div class="field-items">
<div class="field-item even">36265574</div>
</div>
</div>
<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/celiac-disease" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">celiac disease</a></div>
<div class="field-item odd"><a href="/mesh/international-classification-diseases" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">International Classification of Diseases</a></div>
<div class="field-item even"><a href="/mesh/anti-bacterial-agents" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">anti-bacterial agents</a></div>
<div class="field-item odd"><a href="/mesh/proton-pump-inhibitors" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">proton pump inhibitors</a></div>
<div class="field-item even"><a href="/mesh/child" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">child</a></div>
<div class="field-item odd"><a href="/mesh/preschool" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Preschool</a></div>
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<div class="field-item even"><p>Another reason to exercise care when prescribing acid suppression and antibiotics in young children. James W. Mold, MD, MPH</p>
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<div class="field-item even">Free full text</div>
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<div class="views-row views-row-1 views-row-odd views-row-first views-row-last">
<a href="https://www.jpeds.com/article/S0022-3476(22)00900-3/fulltext?dgcid=raven_jbs_aip_email#relatedArticles" class="btn btn-primary" target="_blank">View</a> </div>
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<div class="field-item even" property="content:encoded"><p>Objective<br />
To investigate why certain at-risk individuals develop celiac disease, we examined the association of proton pump inhibitors (PPI), histamine-2 receptor antagonist (H2RA), and antibiotic prescriptions in the first six months of life with an early childhood diagnosis of celiac disease.<br />
Study design<br />
A retrospective cohort study was performed using the Military Healthcare System (MHS) database. Children with a birth record from October 1, 2001- September 30, 2013, were identified. Outpatient prescription records were queried for antibiotic, PPI, and H2RA prescriptions in the first 6 months of life. Cox proportional hazards regression was used to calculate the hazard ratio (HR) of developing CD based on medication exposure. ICD-9 codes identified children with an outpatient visit for celiac disease.<br />
Results<br />
968,524 children met inclusion criteria with 1,704 cases of celiac in this group. Median follow up for the cohort was about 4.5 years. PPI’s (HR, 2.23; 95% CI, 1.76-2.83), H2RA’s (HR, 1.94 95% CI, 1.67-2.26) and antibiotics (HR 1.14 95%CI 1.02-1.28) were all associated with an increased hazard of celiac disease.<br />
Conclusion<br />
There is an increased risk of developing celiac disease if antibiotics, PPI’s and H2RA’s are prescribed in the first 6 months of life. Our study highlights modifiable factors such as medication stewardship that may change the childhood risk of CD.</p>
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<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
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<div class="field-item even">Boechler, M., Susi, A., Hisle-Gorman, E., Rogers, P. L., Nylund, C. M.</div>
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Sat, 22 Oct 2022 05:00:00 +0000Aubrey Delammermore1899 at https://www.rpr.lib.ok.usAssociation of use of cleaning products with respiratory health in a Canadian birth cohort
https://www.rpr.lib.ok.us/resource/association-use-cleaning-products-respiratory-health-canadian-birth-cohort
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
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<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2020-02-18T00:00:00-06:00">February 18, 2020</span></div>
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<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
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<div class="field-item even">Canadian Medical Association Journal</div>
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<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
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<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2020-02-18T00:00:00-06:00">February 18, 2020</span></div>
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<div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix">
<div class="field-label">Issue: </div>
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<div class="field-item even">7</div>
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<div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix">
<div class="field-label">Volume: </div>
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<div class="field-item even">192</div>
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<div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix">
<div class="field-label">Pages: </div>
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<div class="field-item even">E154-E161</div>
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<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
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<div class="field-item even"><a href="https://www.cmaj.ca/content/192/7/E154" target="_blank">Association of use of cleaning products with respiratory health in a Canadian birth cohort</a></div>
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<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
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<div class="field-item even">Clinical Research Results</div>
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<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
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<div class="field-item even">Article</div>
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<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
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<div class="field-item even">https://doi.org/10.1503/cmaj.190819</div>
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<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
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<div class="field-item even"><a href="/tags/respiratory-medicine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Respiratory medicine</a></div>
<div class="field-item odd"><a href="/tags/family-medicine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">family medicine</a></div>
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<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
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<div class="field-item even"><a href="/mesh/child" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">child</a></div>
<div class="field-item odd"><a href="/mesh/preschool" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Preschool</a></div>
<div class="field-item even"><a href="/mesh/odds-ratio" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Odds Ratio</a></div>
<div class="field-item odd"><a href="/mesh/confidence-intervals" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Confidence Intervals</a></div>
<div class="field-item even"><a href="/mesh/respiratory-sounds" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Respiratory Sounds</a></div>
<div class="field-item odd"><a href="/mesh/hypersensitivity" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Hypersensitivity</a></div>
<div class="field-item even"><a href="/mesh/immediate" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Immediate</a></div>
<div class="field-item odd"><a href="/mesh/asthma" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">asthma</a></div>
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<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
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<div class="field-item even"><p>Perhaps it is a combination of excessive cleanliness and exposure to the cleaning products that increase the risk of asthma in children. James W. Mold, MD, MPH</p>
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<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
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<div class="field-item even">Free full text</div>
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<a href="https://www.cmaj.ca/content/192/7/E154" class="btn btn-primary" target="_blank">View</a> </div>
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<div class="field-item even" property="content:encoded"><p>Abstract</p>
<p><strong>BACKGROUND:</strong> Comprehensive longitudinal studies are important for understanding the complex risk factors, pathways, exposures and interactions that lead to the development and persistence of asthma. We aimed to examine associations between use of household cleaning products in early life and childhood respiratory and allergic disease using data from the Canadian Healthy Infant Longitudinal Development (CHILD) Cohort Study.</p>
<p><strong>METHODS:</strong> We summed responses from parental questionnaires that indicated the frequency of use of 26 household cleaning products in the homes of 2022 children from this birth cohort when they were 3–4 months of age to create a cumulative Frequency of Use Score (FUS). We used multivariable logistic regression models to assess whether frequent compared with less frequent use was associated with recurrent wheeze, atopy or asthma diagnosis, as defined by the questionnaire and clinical assessments at age 3 years. Data were collected between 2008 and 2015.</p>
<p><strong>RESULTS:</strong> Children in homes with a higher frequency of use of cleaning products in infancy, as determined by an interquartile range increase, had higher odds of recurrent wheeze (adjusted odds ratio [OR] 1.35, 95% confidence interval [CI] 1.11–1.64), recurrent wheeze with atopy (adjusted OR 1.49, 95% CI 1.02–2.16) and asthma diagnosis (adjusted OR 1.37, 95% CI 1.09–1.70), but no increase in the odds of atopy at age 3 years (adjusted OR 1.14, 95% CI 0.96–1.35). Compared with the lowest tertile of FUS exposure, infants in the highest tertile had higher odds of acquiring asthma. Stratification of the results showed that females had higher ORs than males for all outcomes, although the <em>p</em> values for this sex difference did not reach statistical significance.</p>
<p><strong>INTERPRETATION:</strong> Frequent use of household cleaning products in early life was associated with an increased risk for childhood wheeze and asthma but not atopy at age 3 years. Our findings add to the understanding of how early life exposures to cleaning products may be associated with the development of allergic airway disease and help to identify household behaviours as a potential area for intervention.</p>
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<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
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<div class="field-item even">McCandless, L., Parks, J., Dharma, C., Brook, J., Turvey, S.E., Mandhane, P., Becker, A.B., Kozyrskyj, A.L., Azad, M.B., Moraes, T.J., Lefebvre, D.L., Sears, M.R., Subbarao, P., Scott, J., Takaro, T.K.</div>
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Tue, 18 Feb 2020 16:35:59 +0000Brian Desmarais968 at https://www.rpr.lib.ok.us