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PSA https://www.rpr.lib.ok.us/taxonomy/term/3482/all en Association of Treatment With 5α-Reductase Inhibitors and Prostate Cancer Mortality Among Older Adults https://www.rpr.lib.ok.us/resource/association-treatment-5%CE%B1-reductase-inhibitors-and-prostate-cancer-mortality-among-older <div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Date Added:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-10-19T00:00:00-05:00">October 19, 2019</span></div> </div> </div> <div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix"> <div class="field-label">Journal/Publication:&nbsp;</div> <div class="field-items"> <div class="field-item even">JAMA Network Open</div> </div> </div> <div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix"> <div class="field-label">Publisher:&nbsp;</div> <div class="field-items"> <div class="field-item even">American Medical Association</div> </div> </div> <div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Publication Date:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-10-18T00:00:00-05:00">October 18, 2019</span></div> </div> </div> <div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix"> <div class="field-label">URL:&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="https://www.ncbi.nlm.nih.gov/pubmed/31626312" target="_blank">Association of Treatment With 5α-Reductase Inhibitors and Prostate Cancer Mortality Among Older Adults</a></div> </div> </div> <div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Type:&nbsp;</div> <div class="field-items"> <div class="field-item even">Clinical Research Results</div> </div> </div> <div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Format:&nbsp;</div> <div class="field-items"> <div class="field-item even">Article</div> </div> </div> <div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix"> <div class="field-label">DOI (1):&nbsp;</div> <div class="field-items"> <div class="field-item even">10.1001/jamanetworkopen.2019.13612</div> </div> </div> <div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above"> <div class="field-label">Keywords&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/tags/prostate-cancer" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">prostate cancer</a></div> <div class="field-item odd"><a href="/tags/5-alpha-reductase-inhibitors" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">5-alpha-reductase inhibitors</a></div> <div class="field-item even"><a href="/tags/5%CE%B1-reductase-inhibitors" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">5α-Reductase Inhibitors</a></div> <div class="field-item odd"><a href="/tags/5-aris" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">5-ARIs</a></div> <div class="field-item even"><a href="/tags/prostate-specific-antigen" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">prostate-specific antigen</a></div> <div class="field-item odd"><a href="/tags/psa" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">PSA</a></div> </div> </div> <div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix"> <div class="field-label">PMID (1):&nbsp;</div> <div class="field-items"> <div class="field-item even">31626312</div> </div> </div> <div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above"> <div class="field-label">MeSH&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/mesh/humans" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Humans</a></div> <div class="field-item odd"><a href="/mesh/male" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">male</a></div> <div class="field-item even"><a href="/mesh/prostate-specific-antigen" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Prostate-Specific Antigen</a></div> <div class="field-item odd"><a href="/mesh/dutasteride" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Dutasteride</a></div> <div class="field-item even"><a href="/mesh/finasteride" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Finasteride</a></div> <div class="field-item odd"><a href="/mesh/risk-factors" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">risk factors</a></div> <div class="field-item even"><a href="/mesh/prostatic-neoplasms" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">prostatic neoplasms</a></div> <div class="field-item odd"><a href="/mesh/prostactic-hyperplasia" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Prostactic Hyperplasia</a></div> </div> </div> <div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden"> <div class="field-items"> <div class="field-item even"><p>5-alpha-reductase inhibitors reduce PSA levels, even in patients with prostate cancer, so beware.  James W. Mold, MD, MPH</p> </div> </div> </div> <div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden"> <div class="field-items"> <div class="field-item even">Free full text</div> </div> </div> <div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden"> <div class="field-items"> <div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-ad77edec0f794673d064aaf4d4415c4f"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <a href="https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2753244" class="btn btn-primary" target="_blank">View</a> </div> </div> </div></div> </div> </div> <div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="content:encoded"><p>5α-reductase inhibitors (5-ARIs) are used to treat benign prostatic enlargement, a common condition causing urinary outflow obstruction. They also reduce prostate-specific antigen (PSA) by approximately 50%. Our group has recently published that among US military veterans, 5-ARIs are associated with delays in prostate cancer (PC) diagnoses, higher grade and stage at presentation, and worse PC-specific mortality (PCSM), presumably because of misinterpreted PSA values. We hypothesized that these results are generalizable to the broader US population.</p> </div> </div> </div> <div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Author/s:&nbsp;</div> <div class="field-items"> <div class="field-item even">Kumar, A, Nalawade, V, Riviere, P, Sarkar, RR, Parsons, JK, Murphy, JD, Rose, BS</div> </div> </div> Sat, 19 Oct 2019 15:06:17 +0000 John Bayhi 800 at https://www.rpr.lib.ok.us