Deprecated : Return type of DrupalCacheArray::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 362 Deprecated : Return type of DrupalCacheArray::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 369 Deprecated : Return type of DrupalCacheArray::offsetSet($offset, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 381 Deprecated : Return type of DrupalCacheArray::offsetUnset($offset) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 388
Bone Resorption
en
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Bisphosphonates for Postmenopausal Osteoporosis
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-10-19T00:00:00-05:00">October 19, 2019</span></div>
</div>
</div>
<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
<div class="field-items">
<div class="field-item even">JAMA</div>
</div>
</div>
<div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix">
<div class="field-label">Publisher: </div>
<div class="field-items">
<div class="field-item even">American Medical Association</div>
</div>
</div>
<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-10-17T00:00:00-05:00">October 17, 2019</span></div>
</div>
</div>
<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
<div class="field-items">
<div class="field-item even"><a href="https://www.ncbi.nlm.nih.gov/pubmed/31621799" target="_blank">Bisphosphonates for Postmenopausal Osteoporosis</a></div>
</div>
</div>
<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
<div class="field-items">
<div class="field-item even">Meta-analyses, Reviews, and Guidelines</div>
</div>
</div>
<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
<div class="field-items">
<div class="field-item even">Article</div>
</div>
</div>
<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
<div class="field-items">
<div class="field-item even">10.1001/jama.2019.15781</div>
</div>
</div>
<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
<div class="field-items">
<div class="field-item even"><a href="/tags/post-menopausal-osteoporosis" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">post-menopausal osteoporosis</a></div>
<div class="field-item odd"><a href="/tags/bisphosphonates" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">bisphosphonates</a></div>
<div class="field-item even"><a href="/tags/antiresorptive-agents" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">antiresorptive agents</a></div>
</div>
</div>
<div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix">
<div class="field-label">PMID (1): </div>
<div class="field-items">
<div class="field-item even">31621799</div>
</div>
</div>
<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/humans" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Humans</a></div>
<div class="field-item odd"><a href="/mesh/female" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">female</a></div>
<div class="field-item even"><a href="/mesh/ibandronic-acid" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">ibandronic acid</a></div>
<div class="field-item odd"><a href="/mesh/denosumab" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Denosumab</a></div>
<div class="field-item even"><a href="/mesh/zoledronic-acid" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">zoledronic acid</a></div>
<div class="field-item odd"><a href="/mesh/bone-density-conservation-agents" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Bone Density Conservation Agents</a></div>
<div class="field-item even"><a href="/mesh/raloxifene-hydrochloride" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Raloxifene Hydrochloride</a></div>
<div class="field-item odd"><a href="/mesh/risedronate-sodium" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Risedronate Sodium</a></div>
<div class="field-item even"><a href="/mesh/alendronate" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Alendronate</a></div>
<div class="field-item odd"><a href="/mesh/osteoporosis-postmenopausal" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Osteoporosis, Postmenopausal</a></div>
<div class="field-item even"><a href="/mesh/selective-estrogen-receptor-modulators" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Selective Estrogen Receptor Modulators</a></div>
<div class="field-item odd"><a href="/mesh/creatinine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">creatinine</a></div>
<div class="field-item even"><a href="/mesh/progestins" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Progestins</a></div>
<div class="field-item odd"><a href="/mesh/bone-density" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Bone Density</a></div>
<div class="field-item even"><a href="/mesh/esophageal-achalasia" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Esophageal Achalasia</a></div>
<div class="field-item odd"><a href="/mesh/barrett-esophagus" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Barrett Esophagus</a></div>
<div class="field-item even"><a href="/mesh/hypocalcemia" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Hypocalcemia</a></div>
<div class="field-item odd"><a href="/mesh/osteoclasts" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Osteoclasts</a></div>
<div class="field-item even"><a href="/mesh/esophageal-stenosis" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Esophageal Stenosis</a></div>
<div class="field-item odd"><a href="/mesh/postmenopause" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">postmenopause</a></div>
<div class="field-item even"><a href="/mesh/goals" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Goals</a></div>
<div class="field-item odd"><a href="/mesh/groin" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Groin</a></div>
<div class="field-item even"><a href="/mesh/hip-fractures" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">hip fractures</a></div>
<div class="field-item odd"><a href="/mesh/diphosphonates" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Diphosphonates</a></div>
<div class="field-item even"><a href="/mesh/bone-resorption" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Bone Resorption</a></div>
<div class="field-item odd"><a href="/mesh/gatroesophageal-reflux" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Gatroesophageal Reflux</a></div>
<div class="field-item even"><a href="/mesh/estrogens" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Estrogens</a></div>
<div class="field-item odd"><a href="/mesh/vitamin-d-deficiency" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">vitamin D deficiency</a></div>
<div class="field-item even"><a href="/mesh/peptic-ulcer" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Peptic Ulcer</a></div>
<div class="field-item odd"><a href="/mesh/risk-reduction-behavior" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">risk reduction behavior</a></div>
<div class="field-item even"><a href="/mesh/breast-neoplasms" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">breast neoplasms</a></div>
<div class="field-item odd"><a href="/mesh/biological-therapy" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Biological Therapy</a></div>
<div class="field-item even"><a href="/mesh/femoral-fractures" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Femoral Fractures</a></div>
<div class="field-item odd"><a href="/mesh/osteonecrosis" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Osteonecrosis</a></div>
<div class="field-item even"><a href="/mesh/hydroxyapatites" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Hydroxyapatites</a></div>
<div class="field-item odd"><a href="/mesh/minerals" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Minerals</a></div>
<div class="field-item even"><a href="/mesh/pain" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">pain</a></div>
</div>
</div>
<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
<div class="field-items">
<div class="field-item even"><p>A short, sweet review of how, when, and for how long to treat postmenopausal osteoporosis. James W. Mold, MD, MPH</p>
</div>
</div>
</div>
<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
<div class="field-items">
<div class="field-item even">Commercial full text (fees may apply)</div>
</div>
</div>
<div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden">
<div class="field-items">
<div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-34e53c7a54c37cc309860a9b9cf0720b">
<div class="view-content">
<div class="views-row views-row-1 views-row-odd views-row-first views-row-last">
<a href="https://jamanetwork.com/journals/jama/fullarticle/2753530" class="btn btn-primary" target="_blank">View</a> </div>
</div>
</div></div>
</div>
</div>
<div class="field field-name-body field-type-text-with-summary field-label-hidden">
<div class="field-items">
<div class="field-item even" property="content:encoded"><p>Bisphosphonates are the first-line pharmacologic treatment for postmenopausal osteoporosis and the most commonly prescribed medication for this condition.<a href="https://jamanetwork.com/journals/jama/fullarticle/2753530#jit190026r1">1</a> Bisphosphonates, classified as antiresorptive agents, have a very high affinity for bone mineral and bind to hydroxyapatite crystals on bony surfaces, where they inhibit osteoclast-mediated bone resorption.</p>
</div>
</div>
</div>
<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
<div class="field-items">
<div class="field-item even">Ensrud, KE, Crandall, CJ</div>
</div>
</div>
Sat, 19 Oct 2019 14:38:56 +0000
John Bayhi
798 at https://www.rpr.lib.ok.us