Deprecated : Return type of DrupalCacheArray::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 362 Deprecated : Return type of DrupalCacheArray::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 369 Deprecated : Return type of DrupalCacheArray::offsetSet($offset, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 381 Deprecated : Return type of DrupalCacheArray::offsetUnset($offset) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 388
resolution of cognitive conflict
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Deficient Functioning of Frontostriatal Circuits During the Resolution of Cognitive Conflict in Cannabis-Using Youth
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
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<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-06-26T00:00:00-05:00">June 26, 2019</span></div>
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<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
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<div class="field-item even">Journal of American Academy of Child Adolescent Psychiatry</div>
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<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
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<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-06-01T00:00:00-05:00">June 1, 2019</span></div>
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<div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix">
<div class="field-label">Issue: </div>
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<div class="field-item even">7</div>
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<div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix">
<div class="field-label">Volume: </div>
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<div class="field-item even">58</div>
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<div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix">
<div class="field-label">Pages: </div>
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<div class="field-item even">702-711</div>
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<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
<div class="field-items">
<div class="field-item even"><a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Deficient%20Functioning%20of%20Frontostriatal%20Circuits%20During%20the%20Resolution%20of%20Cognitive%20Conflict%20in%20Cannabis-Using%20Youth" target="_blank">Deficient Functioning of Frontostriatal Circuits During the Resolution of Cognitive Conflict in Cannabis-Using Youth</a></div>
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<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
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<div class="field-item even">Clinical Research Results</div>
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<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
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<div class="field-item even">Article</div>
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<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
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<div class="field-item even"> 10.1016/j.jaac.2018.09.436</div>
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<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
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<div class="field-item even"><a href="/tags/cannabis-use" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">cannabis use</a></div>
<div class="field-item odd"><a href="/tags/frontostriatal-circuits" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">frontostriatal circuits</a></div>
<div class="field-item even"><a href="/tags/functional-magnetic-resonance-imaging" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">functional magnetic resonance imaging</a></div>
<div class="field-item odd"><a href="/tags/resolution-cognitive-conflict" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">resolution of cognitive conflict</a></div>
<div class="field-item even"><a href="/tags/youth" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">youth</a></div>
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<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
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<div class="field-item even"><a href="/mesh/adolescent-psychiatry" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Adolescent Psychiatry</a></div>
<div class="field-item odd"><a href="/mesh/cannabis" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">cannabis</a></div>
<div class="field-item even"><a href="/mesh/prefrontal-cortex" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Prefrontal Cortex</a></div>
<div class="field-item odd"><a href="/mesh/marijuana-smoking" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Marijuana Smoking</a></div>
<div class="field-item even"><a href="/mesh/corpus-striatum" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Corpus Striatum</a></div>
<div class="field-item odd"><a href="/mesh/globus-pallidus" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Globus Pallidus</a></div>
<div class="field-item even"><a href="/mesh/thalamus" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Thalamus</a></div>
<div class="field-item odd"><a href="/mesh/magnetic-resonance-imaging" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Magnetic Resonance Imaging</a></div>
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<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
<div class="field-items">
<div class="field-item even"><p>Functional MRI evidence supporting important adverse effects of marijuana on the brains of adolescents. James W. Mold, MD, MPH</p>
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<div class="field-item even">Free full text</div>
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<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Deficient%20Functioning%20of%20Frontostriatal%20Circuits%20During%20the%20Resolution%20of%20Cognitive%20Conflict%20in%20Cannabis-Using%20Youth" class="btn btn-primary" target="_blank">View</a> </div>
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<div class="field-item even" property="content:encoded"><p>Abstract</p>
<p>OBJECTIVE:</p>
<p>Disturbances in self-regulatory control are involved in the initiation and maintenance of addiction, including cannabis use disorder. In adults, long-term cannabis use is associated with disturbances in frontostriatal circuits during tasks that require the engagement of self-regulatory control, including the resolution of cognitive conflict. Understudied are the behavioral and neural correlates of these processes earlier in the course of cannabis use disentangled from effects of long-term use. The present study investigated the functioning of frontostriatal circuits during the resolution of cognitive conflict in cannabis-using youth.</p>
<p>METHOD:</p>
<p>Functional magnetic resonance imaging data were acquired from 28 cannabis-using youth and 32 age-matched healthy participants during the performance of a Simon task. General linear modeling was used to compare patterns of brain activation during correct responses to conflict stimuli across groups. Psychophysiologic interaction analyses were used to examine conflict-related frontostriatalconnectivity across groups. Associations of frontostriatal activation and connectivity with cannabis use measures were explored.</p>
<p>RESULTS:</p>
<p>Decreased conflict-related activity was detected in cannabis-using versus healthy control youth in frontostriatal regions, including the ventromedial prefrontal cortex, striatum, pallidum, and thalamus. Frontostriatal connectivity did not differ across groups, but negative connectivity between the ventromedial prefrontal cortex and striatum was detected in the 2 groups.</p>
<p>CONCLUSION:</p>
<p>These findings are consistent with previous reports of cannabis-associated disturbances in frontostriatal circuits in adults and point to the specific influence of cannabis on neurodevelopmental changes in youth. Future studies should examine whether frontostriatalfunctioning is a reliable marker of cannabis use disorder severity and a potential target for circuit-based interventions.</p>
<p>Copyright © 2018 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved</p>
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<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
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<div class="field-item even">Cyr, M., Tau, G.Z., Fontaine, M., Levin, F.R., Marsh, R.</div>
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Wed, 26 Jun 2019 19:39:50 +0000
Brian Desmarais
629 at https://www.rpr.lib.ok.us