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donepezil https://www.rpr.lib.ok.us/taxonomy/term/2619/all en Some benefits from donepezil in Alzheimer’s disease https://www.rpr.lib.ok.us/resource/some-benefits-donepezil-alzheimer%E2%80%99s-disease <div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Date Added:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-06-20T00:00:00-05:00">June 20, 2019</span></div> </div> </div> <div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix"> <div class="field-label">Journal/Publication:&nbsp;</div> <div class="field-items"> <div class="field-item even">British Journal of General Practice</div> </div> </div> <div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Publication Date:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2013-03-01T00:00:00-06:00">March 1, 2013</span></div> </div> </div> <div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix"> <div class="field-label">Issue:&nbsp;</div> <div class="field-items"> <div class="field-item even">63</div> </div> </div> <div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix"> <div class="field-label">Volume:&nbsp;</div> <div class="field-items"> <div class="field-item even">608</div> </div> </div> <div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix"> <div class="field-label">Pages:&nbsp;</div> <div class="field-items"> <div class="field-item even">150</div> </div> </div> <div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix"> <div class="field-label">URL:&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582964/" target="_blank">Some benefits from donepezil in Alzheimer’s disease</a></div> </div> </div> <div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Type:&nbsp;</div> <div class="field-items"> <div class="field-item even">Meta-analyses, Reviews, and Guidelines</div> </div> </div> <div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Format:&nbsp;</div> <div class="field-items"> <div class="field-item even">Article</div> </div> </div> <div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix"> <div class="field-label">DOI (1):&nbsp;</div> <div class="field-items"> <div class="field-item even">10.3399/bjgp13X664333</div> </div> </div> <div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above"> <div class="field-label">Keywords&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/tags/donepezil" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">donepezil</a></div> <div class="field-item odd"><a href="/tags/alzheimers-disease" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">alzheimer&#039;s disease</a></div> <div class="field-item even"><a href="/tags/dementia" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">dementia</a></div> <div class="field-item odd"><a href="/tags/brain" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">brain</a></div> <div class="field-item even"><a href="/tags/cognition" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">cognition</a></div> </div> </div> <div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above"> <div class="field-label">MeSH&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/mesh/donepezil" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">donepezil</a></div> <div class="field-item odd"><a href="/mesh/cholinesterase-inhibitors" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Cholinesterase Inhibitors</a></div> <div class="field-item even"><a href="/mesh/acetylcholine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Acetylcholine</a></div> <div class="field-item odd"><a href="/mesh/indans" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Indans</a></div> <div class="field-item even"><a href="/mesh/piperidines" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Piperidines</a></div> <div class="field-item odd"><a href="/mesh/alzheimer-disease" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">alzheimer disease</a></div> <div class="field-item even"><a href="/mesh/dementia" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">dementia</a></div> <div class="field-item odd"><a href="/mesh/cognition" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Cognition</a></div> <div class="field-item even"><a href="/mesh/synaptic-transmission" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Synaptic Transmission</a></div> <div class="field-item odd"><a href="/mesh/brain" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">brain</a></div> </div> </div> <div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden"> <div class="field-items"> <div class="field-item even"><p>RPR Commentary: This is a summary of the data available to date on the effectiveness of donepezil for treatment of patients with Alzheimer’s Disease.  I told patients and their families that if a small improvement in functional abilities would make a huge difference in quality of life (e.g. could remain at home 6 months longer), it is probably worth trying donepezil.  Otherwise the expense and side effects are not worth the very small benefit.  5 to 10mg seems to be enough.   James W. Mold, MD, MPH</p> </div> </div> </div> <div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden"> <div class="field-items"> <div class="field-item even">Free full text</div> </div> </div> <div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden"> <div class="field-items"> <div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-1c76497bbf61ab16ad87ba8a66f79c94"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582964/" class="btn btn-primary" target="_blank">View</a> </div> </div> </div></div> </div> </div> <div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="content:encoded"><p>CLINICAL QUESTION</p> <p>How effective is exercise-based cardiac rehabilitation on mortality, morbidity, and health-related quality of life (QOL) in patients with coronary heart disease (CHD)?</p> <p>BOTTOM LINE</p> <p>Compared to usual care, in medium to longer-term follow-up (≥12 months) exercise-based cardiac rehabilitation was found to be effective in reducing overall and cardiovascular mortality in patients with CHD, and appeared to reduce the risk of hospital admissions in the shorter term (&lt;12 months follow-up). There was no reduction seen in the risk of total myocardial infarction, coronary artery bypass graft, or percutaneous transluminal coronary angioplasty.</p> </div> </div> </div> <div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Author/s:&nbsp;</div> <div class="field-items"> <div class="field-item even">McAvoy, B.R.</div> </div> </div> Thu, 20 Jun 2019 12:57:52 +0000 Brian Desmarais 623 at https://www.rpr.lib.ok.us