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https://www.rpr.lib.ok.us/taxonomy/term/2381/all
enThe Many Faces of Cobalamin (Vitamin B12) Deficiency
https://www.rpr.lib.ok.us/resource/many-faces-cobalamin-vitamin-b12-deficiency-0
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-05-28T00:00:00-05:00">May 28, 2019</span></div>
</div>
</div>
<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
<div class="field-items">
<div class="field-item even">Mayo Clinic Proceedings, Innovations, Quality and Outcomes</div>
</div>
</div>
<div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix">
<div class="field-label">Publisher: </div>
<div class="field-items">
<div class="field-item even">Mayo Clinic</div>
</div>
</div>
<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-06-01T00:00:00-05:00">June 1, 2019</span></div>
</div>
</div>
<div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix">
<div class="field-label">Issue: </div>
<div class="field-items">
<div class="field-item even">2</div>
</div>
</div>
<div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix">
<div class="field-label">Volume: </div>
<div class="field-items">
<div class="field-item even">3</div>
</div>
</div>
<div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix">
<div class="field-label">Pages: </div>
<div class="field-items">
<div class="field-item even">200-214</div>
</div>
</div>
<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
<div class="field-items">
<div class="field-item even"><a href="https://www.sciencedirect.com/science/article/pii/S2542454819300335?via%3Dihub" target="_blank">The Many Faces of Cobalamin (Vitamin B12) Deficiency</a></div>
</div>
</div>
<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
<div class="field-items">
<div class="field-item even">Meta-analyses, Reviews, and Guidelines</div>
</div>
</div>
<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
<div class="field-items">
<div class="field-item even">https://doi.org/10.1016/j.mayocpiqo.2019.03.002</div>
</div>
</div>
<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
<div class="field-items">
<div class="field-item even"><a href="/tags/vitamin-b-12" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vitamin B 12</a></div>
<div class="field-item odd"><a href="/tags/biomarkers" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Biomarkers</a></div>
<div class="field-item even"><a href="/tags/diagnosis" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">diagnosis</a></div>
</div>
</div>
<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/methylmalonic-acid" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Methylmalonic Acid</a></div>
<div class="field-item odd"><a href="/mesh/vitamin-b-12" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vitamin B 12</a></div>
<div class="field-item even"><a href="/mesh/homocysteine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Homocysteine</a></div>
<div class="field-item odd"><a href="/mesh/vitamin-b-12-deficiency" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vitamin B 12 Deficiency</a></div>
<div class="field-item even"><a href="/mesh/anemia" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Anemia</a></div>
<div class="field-item odd"><a href="/mesh/megaloblastic" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Megaloblastic</a></div>
<div class="field-item even"><a href="/mesh/diagnostic-errors" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Diagnostic Errors</a></div>
<div class="field-item odd"><a href="/mesh/diagnostic-tests" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Diagnostic Tests</a></div>
<div class="field-item even"><a href="/mesh/routine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">routine</a></div>
<div class="field-item odd"><a href="/mesh/biomarkers" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Biomarkers</a></div>
</div>
</div>
<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
<div class="field-items">
<div class="field-item even"><p>This is a nice summary of the various manifestations of Vitamin B12 deficiency, an extremely common condition in older people. James W. Mold, MD, MPH</p>
</div>
</div>
</div>
<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
<div class="field-items">
<div class="field-item even">Free full text</div>
</div>
</div>
<div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden">
<div class="field-items">
<div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-5c0124e81f7c3683f702d5d82863409b">
<div class="view-content">
<div class="views-row views-row-1 views-row-odd views-row-first views-row-last">
<a href="https://www.sciencedirect.com/science/article/pii/S2542454819300335?via%253Dihub=" class="btn btn-primary" target="_blank">View</a> </div>
</div>
</div></div>
</div>
</div>
<div class="field field-name-body field-type-text-with-summary field-label-hidden">
<div class="field-items">
<div class="field-item even" property="content:encoded"><p>Although cobalamin (vitamin B12) deficiency was described over a century ago, it is still difficult toestablish the correct diagnosis and prescribe the right treatment. Symptoms related to vitamin B12 deficiency may be diverse and vary from neurologic to psychiatric. A number of individuals with vitamin B12 deficiency may present with the classic megaloblastic anemia.<br />
In clinical practice, many cases of vitamin B12 deficiency are overlooked or sometimes even misdiagnosed. In this review, we describe the heterogeneous disease spectrum of patients with vitamin B12 deficiency in whom the diagnosis was either based on low serum B12 levels, elevated biomarkers like methylmalonic acid and/or homocysteine, or the improvement of clinical symptoms after the institution of parenteral vitamin B12 therapy. We discuss the possible clinical signs and symptoms of patients with B12 deficiency and the various pitfalls of diagnosis and treatment.</p>
</div>
</div>
</div>
<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
<div class="field-items">
<div class="field-item even">Wolffenbuttel, Bruce, Wouters, Hanneke J.C.M., Heiner-Fokkema, Rebecca, van der Klauw, Melanie M.</div>
</div>
</div>
Wed, 29 May 2019 02:15:28 +0000Brian Desmarais578 at https://www.rpr.lib.ok.usThe Many Faces of Cobalamin (Vitamin B12) Deficiency
https://www.rpr.lib.ok.us/resource/many-faces-cobalamin-vitamin-b12-deficiency-0
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-05-28T00:00:00-05:00">May 28, 2019</span></div>
</div>
</div>
<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
<div class="field-items">
<div class="field-item even">Mayo Clinic Proceedings, Innovations, Quality and Outcomes</div>
</div>
</div>
<div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix">
<div class="field-label">Publisher: </div>
<div class="field-items">
<div class="field-item even">Mayo Clinic</div>
</div>
</div>
<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-06-01T00:00:00-05:00">June 1, 2019</span></div>
</div>
</div>
<div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix">
<div class="field-label">Issue: </div>
<div class="field-items">
<div class="field-item even">2</div>
</div>
</div>
<div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix">
<div class="field-label">Volume: </div>
<div class="field-items">
<div class="field-item even">3</div>
</div>
</div>
<div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix">
<div class="field-label">Pages: </div>
<div class="field-items">
<div class="field-item even">200-214</div>
</div>
</div>
<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
<div class="field-items">
<div class="field-item even"><a href="https://www.sciencedirect.com/science/article/pii/S2542454819300335?via%3Dihub" target="_blank">The Many Faces of Cobalamin (Vitamin B12) Deficiency</a></div>
</div>
</div>
<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
<div class="field-items">
<div class="field-item even">Meta-analyses, Reviews, and Guidelines</div>
</div>
</div>
<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
<div class="field-items">
<div class="field-item even">https://doi.org/10.1016/j.mayocpiqo.2019.03.002</div>
</div>
</div>
<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
<div class="field-items">
<div class="field-item even"><a href="/tags/vitamin-b-12" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vitamin B 12</a></div>
<div class="field-item odd"><a href="/tags/biomarkers" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Biomarkers</a></div>
<div class="field-item even"><a href="/tags/diagnosis" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">diagnosis</a></div>
</div>
</div>
<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/methylmalonic-acid" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Methylmalonic Acid</a></div>
<div class="field-item odd"><a href="/mesh/vitamin-b-12" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vitamin B 12</a></div>
<div class="field-item even"><a href="/mesh/homocysteine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Homocysteine</a></div>
<div class="field-item odd"><a href="/mesh/vitamin-b-12-deficiency" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vitamin B 12 Deficiency</a></div>
<div class="field-item even"><a href="/mesh/anemia" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Anemia</a></div>
<div class="field-item odd"><a href="/mesh/megaloblastic" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Megaloblastic</a></div>
<div class="field-item even"><a href="/mesh/diagnostic-errors" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Diagnostic Errors</a></div>
<div class="field-item odd"><a href="/mesh/diagnostic-tests" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Diagnostic Tests</a></div>
<div class="field-item even"><a href="/mesh/routine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">routine</a></div>
<div class="field-item odd"><a href="/mesh/biomarkers" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Biomarkers</a></div>
</div>
</div>
<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
<div class="field-items">
<div class="field-item even"><p>This is a nice summary of the various manifestations of Vitamin B12 deficiency, an extremely common condition in older people. James W. Mold, MD, MPH</p>
</div>
</div>
</div>
<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
<div class="field-items">
<div class="field-item even">Free full text</div>
</div>
</div>
<div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden">
<div class="field-items">
<div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-f98c995b90a68304fa631408b6638b3b">
<div class="view-content">
<div class="views-row views-row-1 views-row-odd views-row-first views-row-last">
<a href="https://www.sciencedirect.com/science/article/pii/S2542454819300335?via%253Dihub=" class="btn btn-primary" target="_blank">View</a> </div>
</div>
</div></div>
</div>
</div>
<div class="field field-name-body field-type-text-with-summary field-label-hidden">
<div class="field-items">
<div class="field-item even" property="content:encoded"><p>Although cobalamin (vitamin B12) deficiency was described over a century ago, it is still difficult toestablish the correct diagnosis and prescribe the right treatment. Symptoms related to vitamin B12 deficiency may be diverse and vary from neurologic to psychiatric. A number of individuals with vitamin B12 deficiency may present with the classic megaloblastic anemia.<br />
In clinical practice, many cases of vitamin B12 deficiency are overlooked or sometimes even misdiagnosed. In this review, we describe the heterogeneous disease spectrum of patients with vitamin B12 deficiency in whom the diagnosis was either based on low serum B12 levels, elevated biomarkers like methylmalonic acid and/or homocysteine, or the improvement of clinical symptoms after the institution of parenteral vitamin B12 therapy. We discuss the possible clinical signs and symptoms of patients with B12 deficiency and the various pitfalls of diagnosis and treatment.</p>
</div>
</div>
</div>
<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
<div class="field-items">
<div class="field-item even">Wolffenbuttel, Bruce, Wouters, Hanneke J.C.M., Heiner-Fokkema, Rebecca, van der Klauw, Melanie M.</div>
</div>
</div>
Wed, 29 May 2019 02:15:26 +0000Brian Desmarais577 at https://www.rpr.lib.ok.us