sexually transmitted diseases

Doxycycline postexposure prophylaxis to prevent bacterial sexually transmitted infections

Alex Haga — Tue, 27 May 2025 13:12:27 +0000

Date Added:

May 27, 2025

Journal/Publication:

Canadian Medical Association Journal

Publication Date:

May 20, 2025

Issue:

Volume:

197

Pages:

E534-E535

URL:

Doxycycline postexposure prophylaxis to prevent bacterial sexually transmitted infections

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

DOI (1):

10.1503/cmaj.250128

Keywords

doxycycline

prophylaxis

sexually transmitted diseases

Chlamydia

PMID (1):

40393712

MeSH

Doxycycline

sexually transmitted diseases

chlamydia

A concise review of the use of doxycycline for STI prevention following unprotected intercourse. James W. Mold, MD, MPH

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No abstract available.

Author/s:

Victor Leung, Junine Toy, Peter Phillips, Julio S G Montaner

Adolescent-Centered Sexual and Reproductive Health Communication

Alex Haga — Thu, 23 Jan 2025 19:37:47 +0000

Date Added:

January 23, 2025

Journal/Publication:

JAMA

Publication Date:

January 21, 2025

URL:

Adolescent-Centered Sexual and Reproductive Health Communication

Type:

Best Local Practices

Format:

Article

DOI (1):

10.1001/jama.2024.24246

Keywords

contraception

adolescent

sexual behavior

PMID (1):

39693089

MeSH

adolescent

Reproductive Health

Sexual Behavior

sexually transmitted diseases

Contraception

Tips for talking with teens about sex and pregnancy. James W. Mold, MD, MPH

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This JAMA Insights explores how clinicians can effectively communicate person-centered health care information to adolescents regarding sexual and reproductive health, contraception, and sexually transmitted infection testing and treatment.

Author/s:

Bianca A Allison, Tracey A Wilkinson, Julie Maslowsky

Doxycycline Postexposure Prophylaxis to Prevent Bacterial Sexually Transmitted Infection

Alex Haga — Sun, 05 Jan 2025 21:47:03 +0000

Date Added:

January 5, 2025

Journal/Publication:

JAMA

Publication Date:

January 19, 2025

URL:

Doxycycline Postexposure Prophylaxis to Prevent Bacterial Sexually Transmitted Infection

Type:

Meta-analyses, Reviews, and Guidelines, Public Health Announcements

Format:

Article

DOI (1):

10.1001/jama.2024.24540

Keywords

sexually transmitted diseases

doxycycline

PMID (1):

39699880

MeSH

sexually transmitted diseases

Doxycycline

A guideline from the CDC regarding the use of doxycycline post exposure to STIs to prevent infection. James W. Mold, MD, MPH

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This JAMA Guidelines Synopsis summarizes the 2024 Centers for Disease Control and Prevention guidelines on use of doxycycline postexposure prophylaxis (doxyPEP) for bacterial sexually transmitted infection prevention.

Author/s:

John Flores, Andrew M Davis, Aniruddha Hazra

Adolescent-Centered Sexual and Reproductive Health Communication

Alex Haga — Sun, 05 Jan 2025 21:43:38 +0000

Date Added:

January 5, 2025

Journal/Publication:

JAMA

Publication Date:

December 18, 2024

URL:

Adolescent-Centered Sexual and Reproductive Health Communication

Type:

Clinical Decision Aids, Patient Education Materials

Format:

Article

DOI (1):

10.1001/jama.2024.24246

Keywords

adolescent

sexuality

sexually transmitted diseases

PMID (1):

39693089

MeSH

sexually transmitted diseases

A useful list of internet sources for clinicians, parents, and adolescents regarding sexual and reproductive health concerns. James W. Mold, MD, MPH

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Author/s:

Bianca A Allison, Tracey A Wilkinson, Julie Maslowsky

Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society-USA Panel

Alex Haga — Sun, 08 Dec 2024 20:41:28 +0000

Date Added:

December 8, 2024

Journal/Publication:

JAMA

Publication Date:

December 1, 2024

URL:

Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society-USA Panel

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

DOI (1):

10.1001/jama.2024.24543

Keywords

HIV Infections

HIV

sexually transmitted diseases

PMID (1):

39616604

MeSH

HIV infections

sexually transmitted diseases

2024 guidelines for the use of anti-retrovirals for prevention and treatment of HIV infections. James W. Mold, MD, MPH

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Importance: New data and new antiretroviral drugs and formulations continue to become available for the prevention and management of HIV infection.

Objective: To provide updated recommendations for HIV treatment and clinical management and HIV prevention.

Methods: A panel of volunteer expert physician scientists were appointed to provide updated consensus recommendations for 2024. Relevant evidence in the literature since the last report was identified from PubMed and Embase searches (which initially yielded 3998 unique citations, of which 249 were considered relevant); from ongoing monitoring of the literature by the panel members; from data submitted by product manufacturers; and from studies presented at peer-reviewed scientific conferences between June 2022 and October 2024.

Findings: Antiretroviral therapy continues to be recommended for all individuals with HIV. For most people with HIV, initial regimens composed of an integrase strand transfer inhibitor (InSTI), specifically bictegravir or dolutegravir, with 2 (and in some cases 1) nucleoside or nucleotide reverse transcriptase inhibitors are recommended. Recommendations are made for those with particular clinical circumstances, such as pregnancy and active opportunistic diseases, as well as for those unable to take InSTIs. Regimens may need to be changed for virologic failure, adverse effects, convenience, or cost, among other reasons. Long-acting injectable therapy is available for those who prefer not to take daily oral medications and for people struggling with adherence to daily therapy. Recommendations are provided for laboratory monitoring, management of substance use disorders and weight changes, as well as use of statins for cardiovascular disease prevention. For HIV prevention, oral (daily or intermittent) and injectable long-acting medications are effective options for people at increased likelihood of HIV exposure. Further, new tools for maintaining health and well-being among people with HIV, such as doxycycline postexposure prophylaxis to avert sexually transmitted infection, and strategies to treat substance use disorders, are recommended. Disparities in HIV acquisition and care access are discussed and solutions proposed.

Conclusions: New approaches for treating and preventing HIV offer additional tools to help end the HIV epidemic, but achieving this goal depends on addressing disparities and inequities in access to care.

Author/s:

Rajesh T Gandhi, Raphael J Landovitz, Paul E Sax, Davey M Smith

What Is Genital Herpes?

Alex Haga — Sun, 08 Dec 2024 20:37:43 +0000

Date Added:

December 8, 2024

Journal/Publication:

JAMA

Publication Date:

November 27, 2024

URL:

What Is Genital Herpes?

Type:

Patient Education Materials

Format:

Article

DOI (1):

10.1001/jama.2024.21537

Keywords

genital herpes simplex infection

genital

herpes

PMID (1):

39602180

MeSH

herpes genitalis

Herpes Labialis

Persistent Infection

sexually transmitted diseases

Genitalia

Information for patients about genital herpes simplex infection. James W. Mold, MD, MPH

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This JAMA Patient Page describes genital herpes and its symptoms, diagnosis, treatment, and prevention measures.

Author/s:

Rebecca Voelker

Genital Herpes

Alex Haga — Tue, 20 Aug 2024 20:03:33 +0000

Date Added:

August 20, 2024

Journal/Publication:

JAMA

Publication Date:

August 14, 2024

URL:

Genital Herpes

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

DOI (1):

10.1001/jama.2024.12743

Keywords

sexually transmitted diseases

urinary tract infections

herpes

genital herpes

PMID (1):

39141407

MeSH

sexually transmitted diseases

urinary tract infections

Genitalia

A review of what we currently understand about genital herpes simplex infections. James W Mold, MD, MPH

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This JAMA Insights examines the history, diagnosis, prevention, and stigma of genital herpes infection in the US and explores treatments such as suppressive therapy.

Author/s:

Christine Johnston, Anna Wald

Sexually Transmitted Infections Treatment Guidelines, 2021

Saige Blanchard — Fri, 23 Jul 2021 05:00:00 +0000

Date Added:

July 23, 2021

Journal/Publication:

Morbidity and Mortality Weekly Report

Publisher:

Centers for Disease Control and Prevention

Publication Date:

July 23, 2021

Issue:

Volume:

Pages:

1-187

URL:

Sexually Transmitted Infections Treatment Guidelines, 2021

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

Keywords

Sexually Transmitted Infection

MeSH

sexually transmitted diseases

Mycoplasma genitalium

neisseria gonorrhoeae

Pelvic Inflammatory Disease

Sexual and Gender Minorities

CDC 2021 Guidance for Treatment of Sexually Transmitted Infections. James W. Mold, MD, MPH

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The term “sexually transmitted infection” (STI) refers to a pathogen that causes infection through sexual contact, whereas the term “sexually transmitted disease” (STD) refers to a recognizable disease state that has developed from an infection. Physicians and other health care providers have a crucial role in preventing and treating STIs. These guidelines are intended to assist with that effort. Although the guidelines emphasize treatment, prevention strategies and diagnostic recommendations also are discussed.

This report updates Sexually Transmitted Diseases Treatment Guidelines, 2015 (1) and should be regarded as a source of clinical guidance rather than prescriptive standards. Health care providers should always consider the clinical circumstances of each person in the context of local disease prevalence. These guidelines are applicable to any patient care setting that serves persons at risk for STIs, including family planning clinics, HIV care clinics, correctional health care settings, private physicians’ offices, Federally Qualified Health Centers, clinics for adolescent care, and other primary care facilities. These guidelines are focused on treatment and counseling and do not address other community services and interventions that are essential to STI and HIV prevention efforts.

These STI treatment guidelines complement Recommendations for Providing Quality Sexually Transmitted Diseases Clinical Services, 2020 (2) regarding quality clinical services for STIs in primary care and STD specialty care settings. This guidance specifies operational determinants of quality services in various clinical settings, describes on-site treatment and partner services, and indicates when STI-related conditions should be managed through consultation with or referral to a specialist.

Author/s:

Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., Bolan, G. A.

Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020

Carly Hughes — Sat, 16 Jan 2021 20:18:42 +0000

Date Added:

January 16, 2021

Journal/Publication:

Morbidity and Mortality Weekly Report

Publisher:

Center for Disease Control and Prevention

Publication Date:

December 18, 2020

Issue:

Volume:

Pages:

1911-1916

URL:

Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020

Type:

Meta-analyses, Reviews, and Guidelines, Public Health Announcements

Format:

Article

Keywords

gonorrhea

sexually transmitted infections

treatment

MeSH

gonorrhea

sexually transmitted diseases

Treatment

2020 CDC Guidance regarding treatment of gonococcal infections. James W. Mold, MD, MPH

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Not available

Author/s:

Syr, Sancta St., Lindley, Barbee, Workowski, Kimberly A., Bachmann, Laura, Pham, Cau, Schlanger, Karen, Torrone, Elizabeth

Sexually Transmitted Infections: Behavioral Counseling

Brian Desmarais — Thu, 20 Aug 2020 14:37:26 +0000

Date Added:

August 20, 2020

Publisher:

U.S. Preventive Services Task Force

Publication Date:

August 18, 2020

URL:

Sexually Transmitted Infections: Behavioral Counseling

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Web Page

MeSH

sexually transmitted diseases

counseling

adolescent

The USPSTF now recommends behavioral counseling regarding prevention of STIs for all sexually active adolescents and adults at risk for STIs (a category B recommendation). James W. Mold, MD, MPH

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Not available.

Sexually Transmitted Infections

Tracy Ashby — Thu, 11 Apr 2019 05:00:00 +0000

Date Added:

April 11, 2019

Journal/Publication:

American Family Physician

Publisher:

American Academy of Family Physicians

URL:

Sexually Transmitted Infections

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Web Page

Keywords

sexually transmitted infections

human papillomavirus

MeSH

sexually transmitted diseases

acquired immunodeficiency syndrome

hepatitis A

hepatitis

This is a set of links to all recent American Family Physician/AAFP articles about sexually transmitted disease. James W. Mold, MD, MPH

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This collection features the best content from AFP, as identified by the AFP editors, on sexually transmitted disease and related issues, including chlamydia, genital herpes, gonorrhea, human papillomavirus, and syphilis. New research may affect the interpretation and application of this material. Clinical judgment is advised. Note that AFP content published within the past 12 months is accessible to AAFP members and paid subscribers only.
Note: This topic collection does not include human immunodeficiency virus (see separate topic collection on HIV/AIDS) or hepatitis (see separate topic collection on Hepatitis and Other Liver Diseases).