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https://www.rpr.lib.ok.us/taxonomy/term/1971/all
enPsyllium fiber improves glycemic control proportional to loss of glycemic control: a meta-analysis of data in euglycemic subjects, patients at risk of type 2 diabetes mellitus, and patients being treated for type 2 diabetes mellitus
https://www.rpr.lib.ok.us/resource/psyllium-fiber-improves-glycemic-control-proportional-loss-glycemic-control-meta-analysis
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-04-09T00:00:00-05:00">April 9, 2019</span></div>
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</div>
<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
<div class="field-items">
<div class="field-item even">The American Journal of Clinical Nutrition</div>
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<div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix">
<div class="field-label">Publisher: </div>
<div class="field-items">
<div class="field-item even">American Society for Nutrition</div>
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<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2015-11-11T00:00:00-06:00">November 11, 2015</span></div>
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<div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix">
<div class="field-label">Issue: </div>
<div class="field-items">
<div class="field-item even">6</div>
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<div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix">
<div class="field-label">Volume: </div>
<div class="field-items">
<div class="field-item even">102</div>
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<div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix">
<div class="field-label">Pages: </div>
<div class="field-items">
<div class="field-item even">1604-1614</div>
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<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
<div class="field-items">
<div class="field-item even"><a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Psyllium%20fiber%20improves%20glycemic%20control%20proportional%20to%20loss%20of%20glycemic%20control%3A%20a%20meta-analysis%20of%20data%20in%20euglycemic%20subjects%2C%20patients%20at%20risk%20of%20type%202%20diabetes%20mellitus%2C%20and%20patients%20being%20treated%20for%20type%202%20diabetes%20mellitus" target="_blank">Psyllium fiber improves glycemic control proportional to loss of glycemic control: a meta-analysis of data in euglycemic subjects, patients at risk of type 2 diabetes mellitus, and patients being treated for type 2 diabetes mellitus</a></div>
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<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
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<div class="field-item even">Meta-analyses, Reviews, and Guidelines</div>
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</div>
<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
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<div class="field-item even">Article</div>
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<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
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<div class="field-item even">10.3945/ajcn.115.106989</div>
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</div>
<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
<div class="field-items">
<div class="field-item even"><a href="/tags/diabetes" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">diabetes</a></div>
<div class="field-item odd"><a href="/tags/fiber" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">fiber</a></div>
<div class="field-item even"><a href="/tags/glycemic" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">glycemic</a></div>
<div class="field-item odd"><a href="/tags/glycemic-control" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">glycemic control</a></div>
<div class="field-item even"><a href="/tags/meta-analysis" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">meta-analysis</a></div>
<div class="field-item odd"><a href="/tags/metabolic-syndrome" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">metabolic syndrome</a></div>
<div class="field-item even"><a href="/tags/psyllium" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">psyllium</a></div>
<div class="field-item odd"><a href="/tags/type-2-diabetes" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">type 2 diabetes</a></div>
</div>
</div>
<div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix">
<div class="field-label">PMID (1): </div>
<div class="field-items">
<div class="field-item even">26561625</div>
</div>
</div>
<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/diabetes-mellitus-type-2" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">diabetes mellitus, type 2</a></div>
<div class="field-item odd"><a href="/mesh/psyllium" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">psyllium</a></div>
<div class="field-item even"><a href="/mesh/hypolipidemic-agents" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">hypolipidemic agents</a></div>
<div class="field-item odd"><a href="/mesh/blood-glucose" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">blood glucose</a></div>
<div class="field-item even"><a href="/mesh/dietary-fiber" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">dietary fiber</a></div>
<div class="field-item odd"><a href="/mesh/postprandial-period" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">postprandial period</a></div>
<div class="field-item even"><a href="/mesh/glycated-hemoglobin-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">glycated hemoglobin a</a></div>
<div class="field-item odd"><a href="/mesh/cholesterol" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">cholesterol</a></div>
</div>
</div>
<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
<div class="field-items">
<div class="field-item even"><p>This 2015 meta-analysis found that the addition of 5 – 10 gm of psyllium husks taken before each meal reduced A1cs in type 2 diabetics by an average of 1%, comparable to most diabetes meds. Most patients will have to work their way up to that dose gradually I suspect. James W. Mold, MD, MPH</p>
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<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
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<div class="field-item even">Free full text</div>
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<a href="https://academic.oup.com/ajcn/article/102/6/1604/4555168" class="btn btn-primary" target="_blank">View</a> </div>
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<div class="field-item even" property="content:encoded"><p>BACKGROUND:</p>
<p>A number of health benefits are associated with intake of soluble, viscous, gel-forming fibers, including reduced serum cholesterol and the attenuation of postprandial glucose excursions.</p>
<p>OBJECTIVE:</p>
<p>We assess the effects of psyllium, which is a soluble, gel-forming, nonfermented fibersupplement, on glycemic control in patients who were being treated for type 2 diabetes mellitus (T2DM) and in patients who were at risk of developing T2DM.</p>
<p>DESIGN:</p>
<p>A comprehensive search was performed of available published literature (Scopus scientific database) and clinical records stored by Procter & Gamble with the use of key search terms to identify clinical studies that assessed the glycemic effects of psyllium in nondiabetic, pre-T2DM, and T2DM patients.</p>
<p>RESULTS:</p>
<p>We identified 35 randomized, controlled, clinical studies that spanned 3 decades and 3 continents. These data were assessed in 8 meta-analyses. In patients with T2DM, multiweek studies (psyllium dosed before meals) showed significant improvement in both the fasting blood glucose (FBG) concentration (-37.0 mg/dL; P < 0.001) and glycated hemoglobin (HbA1c) [-0.97% (-10.6 mmol/mol); P = 0.048]. Glycemic effects were proportional to baseline FBG; no significant glucose lowering was observed in euglycemic subjects, a modest improvement was observed in subjects with pre-T2DM, and the greatest improvement was observed in subjects who were being treated for T2DM.</p>
<p>CONCLUSIONS:</p>
<p>These data indicate that psyllium would be an effective addition to a lifestyle-intervention program. The degree of psyllium's glycemic benefit was commensurate with the loss of glycemic control. Because the greatest effect was seen in patients who were being treated for T2DM, additional studies are needed to determine how best to incorporate psyllium into existing prevention and treatment algorithms with concomitant hypoglycemic medications.</p>
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<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
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<div class="field-item even">Gibb, Roger D., McRorie, Johnson W., Russell, Darrell A., Hasselblad, Vic, D'Alessio, David A.</div>
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Tue, 09 Apr 2019 05:00:00 +0000Tracy Ashby493 at https://www.rpr.lib.ok.us