hepatitis C

In the United States, hepatitis C virus (HCV) infection affects more than 2 million adults and is the leading cause of liver-related mortality. Therapies that eradicate HCV may prevent progression to cirrhosis, liver decompensation, hepatocellular carcinoma, need for liver transplant, and death. HCV eradication also appears to reduce the risk of extrahepatic diseases, including cryoglobulinemic vasculitis and cardiovascularevents. Direct-acting antivirals (DAAs), oral drugs that target multiple mechanisms of the HCV lifecycle, have been usedincombination since 2013. Because of their efficacy and safety, the use of DAAshas substantiall yimproved HCV treatment and made HCV eradication possible for most patients, including patients with HIV infection, severe renal and hepatic impairment, and history of organ transplantation. Individuals living with HCV should be treated to reduce liver-related and all-cause morbidity and mortality and to prevent HCV transmission...

Author/s:

Kristen, Naggie, Susanna

Hepatitis (and Other Liver Diseases)

Jeffrey Wilson — Sat, 06 Apr 2019 18:28:04 +0000

Date Added:

April 6, 2019

Journal/Publication:

American Family Physician

Publisher:

American Academy of Family Physicians

Publication Date:

March 1, 2019

URL:

Hepatitis (and Other Liver Diseases)

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Web Page

Keywords

MeSH

A single link to content related to various types of hepatitis previously published in the American Family Physician. James W. Mold, MD, MPH

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This collection features the best content from AFP, as identified by the AFP editors, on hepatitis and other liver disease and related issues, including cirrhosis, chronic liver failure, hemochromatosis, hepatitis A, hepatitis B, hepatitis C, jaundice, and nonalcoholic fatty liver disease. New research may affect the interpretation and application of this material. Clinical judgment is advised. Note that AFP content published within the past 12 months is accessible to AAFP members and paid subscribers only.