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https://www.rpr.lib.ok.us/taxonomy/term/1312/all
enEffect of glycaemic control on cardiovascular disease in individuals with type 2 diabetes with pre-existing cardiovascular disease: A systematic review and meta-analysis
https://www.rpr.lib.ok.us/resource/effect-glycaemic-control-cardiovascular-disease-individuals-type-2-diabetes-pre-existing
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-01-06T00:00:00-06:00">January 6, 2019</span></div>
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<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
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<div class="field-item even">Diabetes, Obesity and Metabolism </div>
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<div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix">
<div class="field-label">Publisher: </div>
<div class="field-items">
<div class="field-item even">John Wiley & Sons, Inc.</div>
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<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
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<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2018-11-13T00:00:00-06:00">November 13, 2018</span></div>
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<div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix">
<div class="field-label">Pages: </div>
<div class="field-items">
<div class="field-item even">1-4</div>
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<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
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<div class="field-item even"><a href="https://onlinelibrary.wiley.com/doi/full/10.1111/dom.13581" target="_blank">Effect of glycaemic control on cardiovascular disease in individuals with type 2 diabetes with pre-existing cardiovascular disease: A systematic review and meta-analysis</a></div>
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</div>
<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
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<div class="field-item even">Meta-analyses, Reviews, and Guidelines, Meta-analyses, Reviews, and Guidelines</div>
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<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
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<div class="field-item even">Article</div>
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<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
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<div class="field-item even">10.1111/dom.13581</div>
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<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
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<div class="field-item even"><a href="/tags/cardiovascular-disease" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">cardiovascular disease</a></div>
<div class="field-item odd"><a href="/tags/glucose-control" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">glucose control</a></div>
<div class="field-item even"><a href="/tags/intensive" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">intensive</a></div>
<div class="field-item odd"><a href="/tags/type-2-diabetes" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">type 2 diabetes</a></div>
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<div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix">
<div class="field-label">PMID (1): </div>
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<div class="field-item even">30426626</div>
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<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/diabetes-mellitus-type-2" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">diabetes mellitus, type 2</a></div>
<div class="field-item odd"><a href="/mesh/disease-cardiovascular" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">disease, cardiovascular</a></div>
<div class="field-item even"><a href="/mesh/blood-glucose" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">blood glucose</a></div>
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<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
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<div class="field-item even"><p>Glycemic control in patients with type 2 diabetes mellitus and cardiovascular disease did not reduce the rate of subsequent adverse cardiovascular events in this large meta-analysis which included patients on metformin but not some of the newest hypoglycemic agents. Reasons to control blood sugar levels in type 2 diabetics are: 1) to reduce symptoms related to dehydration; 2) to reduce the risk or severity of certain infections (e.g. Monilial infections and possibly UTIs), 3) to reduce the risk of hyperosmolar non-ketotic coma; and 4) to reduce the risk of microvascular complications over the long term.</p>
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<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
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<div class="field-item even">Free full text</div>
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<div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-05027568eab78f65d22aab40cb2a8822">
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<div class="views-row views-row-1 views-row-odd views-row-first views-row-last">
<a href="https://www.ncbi.nlm.nih.gov/pubmed/30426626?dopt=Abstract" class="btn btn-primary" target="_blank">View</a> </div>
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<div class="field-item even" property="content:encoded"><p>The role of intensive glucose control in people with type 2 diabetes and pre‐existing cardiovascular disease (CVD) is controversial. The aim of this systematic review and meta‐analysis was to determine in a subset of people with type 2 diabetes and pre‐existing CVD, the CV effect of intensive glucose control versus standard of care. We searched Medline, the Cochrane library, EMBASE and the National Institutes of Health Trial registration database for randomized controlled trials that evaluated the effect of intensive glucose control versus standard glucose control in people with type 2 diabetes on incident CVD. Data were extracted using a structured form. When data were not available in the publications, authors were contacted. Eight trials involving 8339 participants were included. Among adults with type 2 diabetes and pre‐existing CVD, there was no difference in the risk of CV events in those allocated to intensive glucose control compared with those in the standard care arm (relative risk 0.98, 95% confidence interval 0.87‐1.09). In conclusion, in people with diabetes and pre‐existing CVD, intensive glucose control versus standard care had a neutral effect on incident CV events.</p>
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<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
<div class="field-items">
<div class="field-item even">Barer, Yael, Cohen, Ohad, Cukierman-Yaffe, Tali</div>
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Sun, 06 Jan 2019 06:00:00 +0000Tracy Ashby307 at https://www.rpr.lib.ok.us