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ablation https://www.rpr.lib.ok.us/taxonomy/term/12476/all en Should We Continue Anticoagulation Indefinitely after Catheter Ablation of Atrial Fibrillation? https://www.rpr.lib.ok.us/resource/should-we-continue-anticoagulation-indefinitely-after-catheter-ablation-atrial-fibrillation <div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Date Added:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2025-12-11T00:00:00-06:00">December 11, 2025</span></div> </div> </div> <div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix"> <div class="field-label">Journal/Publication:&nbsp;</div> <div class="field-items"> <div class="field-item even">New England Journal of Medicine</div> </div> </div> <div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Publication Date:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2025-12-01T00:00:00-06:00">December 1, 2025</span></div> </div> </div> <div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix"> <div class="field-label">URL:&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="https://clinician.nejm.org/continue-anticoagulation-indefinitely-catheter-ablation-atrial-fibrillation-CLINjwNA59479?query=cl_we&amp;cid=DM2429966_Non_Subscriber&amp;bid=-1033623924" target="_blank">Should We Continue Anticoagulation Indefinitely after Catheter Ablation of Atrial Fibrillation?</a></div> </div> </div> <div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Type:&nbsp;</div> <div class="field-items"> <div class="field-item even">Clinical Research Results</div> </div> </div> <div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above"> <div class="field-label">Keywords&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/tags/anticoagulants" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">anticoagulants</a></div> <div class="field-item odd"><a href="/tags/ablation" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Ablation</a></div> <div class="field-item even"><a href="/tags/atrial-fibrillation" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">atrial fibrillation</a></div> </div> </div> <div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above"> <div class="field-label">MeSH&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/mesh/anticoagulants" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">anticoagulants</a></div> <div class="field-item odd"><a href="/mesh/ablation" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">ablation</a></div> <div class="field-item even"><a href="/mesh/atrial-fibrillation" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">atrial fibrillation</a></div> </div> </div> <div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden"> <div class="field-items"> <div class="field-item even"><p>It is reasonable to stop anticoagulants post successful ablation if there has been no reoccurrence of atrial fibrillation for 1 year or more. James W. Mold, MD, MPH</p> </div> </div> </div> <div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden"> <div class="field-items"> <div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-8d1f51e44540d37da8b80f41ec798cd8"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <a href="https://clinician.nejm.org/continue-anticoagulation-indefinitely-catheter-ablation-atrial-fibrillation-CLINjwNA59479?query=cl_we&amp;cid=DM2429966_Non_Subscriber&amp;bid=-1033623924" class="btn btn-primary" target="_blank">View</a> </div> </div> </div></div> </div> </div> <div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="content:encoded"><p>Context<br /> Current guidelines recommend indefinite anticoagulation after ablation of atrial fibrillation (AF) in patients with a CHA2DS2-VASc score ≥2–3, but few data support this practice. In a recent randomized trial (ALONE-AF), stopping anticoagulation 1 year after ablation did not raise stroke risk; now, another trial (OCEAN) has examined the same issue.</p> <p>Researchers randomized 1300 patients with successful catheter ablation (no AF at 1 year clinically or on Holter monitoring) to receive rivaroxaban 15 mg or low-dose aspirin. Exclusion criteria included severe renal disease, hypercoagulability, and age &gt;85. The mean CHA2DS2-VASc score was 2.2; only 10% of patients had scores ≥4.</p> <p>Key Results<br /> At 3 years, the incidence of the composite outcome (stroke, systemic embolism, or new covert stroke on MRI) did not differ significantly between treatment groups (0.8% with rivaroxaban and 1.4% with aspirin).<br /> Major bleeding occurred slightly more often with rivaroxaban than with aspirin (1.6% and 0.6%), but this did not reach significance.</p> </div> </div> </div> <div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Author/s:&nbsp;</div> <div class="field-items"> <div class="field-item even">Mark S. Link</div> </div> </div> Thu, 11 Dec 2025 22:10:24 +0000 Megan George 2847 at https://www.rpr.lib.ok.us