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https://www.rpr.lib.ok.us/taxonomy/term/1220/all
enA meta-analysis of alcohol consumption and the risk of 15 diseases
https://www.rpr.lib.ok.us/resource/meta-analysis-alcohol-consumption-and-risk-15-diseases
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2019-01-02T00:00:00-06:00">January 2, 2019</span></div>
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</div>
<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
<div class="field-items">
<div class="field-item even">Preventative Medicine</div>
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<div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix">
<div class="field-label">Publisher: </div>
<div class="field-items">
<div class="field-item even">Elsevier</div>
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</div>
<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
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<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2004-05-01T00:00:00-05:00">May 1, 2004</span></div>
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<div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix">
<div class="field-label">Issue: </div>
<div class="field-items">
<div class="field-item even">5</div>
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<div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix">
<div class="field-label">Volume: </div>
<div class="field-items">
<div class="field-item even">38</div>
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<div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix">
<div class="field-label">Pages: </div>
<div class="field-items">
<div class="field-item even">613-619</div>
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<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
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<div class="field-item even"><a href="https://www.ncbi.nlm.nih.gov/pubmed/15066364" target="_blank">A meta-analysis of alcohol consumption and the risk of 15 diseases</a></div>
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</div>
<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
<div class="field-items">
<div class="field-item even">Meta-analyses, Reviews, and Guidelines</div>
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</div>
<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
<div class="field-items">
<div class="field-item even">Article</div>
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<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
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<div class="field-item even">10.1016/j.ypmed.2003.11.027</div>
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<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
<div class="field-items">
<div class="field-item even"><a href="/tags/alcohol" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">alcohol</a></div>
<div class="field-item odd"><a href="/tags/alcohol-abuse" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">alcohol abuse</a></div>
</div>
</div>
<div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix">
<div class="field-label">PMID (1): </div>
<div class="field-items">
<div class="field-item even">15066364</div>
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</div>
<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/alcohol-drinking" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">alcohol drinking</a></div>
<div class="field-item odd"><a href="/mesh/pancreatitis-chronic" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">pancreatitis, chronic</a></div>
<div class="field-item even"><a href="/mesh/coronary-disease" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">coronary disease</a></div>
<div class="field-item odd"><a href="/mesh/neoplasms-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">neoplasms,</a></div>
<div class="field-item even"><a href="/mesh/hypertension" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">hypertension</a></div>
<div class="field-item odd"><a href="/mesh/violence" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">violence</a></div>
</div>
</div>
<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
<div class="field-items">
<div class="field-item even"><p>This meta-analysis found strong dose response relationships between alcohol intake and cancers of the <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/oral-cavity" target="_blank" title="Learn more about Oral Cavity">oral cavity</a>, esophagus, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/larynx" target="_blank" title="Learn more about Larynx">larynx</a>, as well as hypertension, <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/liver-cirrhosis" target="_blank" title="Learn more about Liver Cirrhosis">liver cirrhosis</a>, <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/chronic-pancreatitis" target="_blank" title="Learn more about Chronic Pancreatitis">chronic pancreatitis</a>, and injuries and violence. Note: Alcohol abuse is a fairly common cause of difficult to treat hypertension.</p>
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<div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden">
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<div class="views-row views-row-1 views-row-odd views-row-first views-row-last">
<a href="https://www.ncbi.nlm.nih.gov/pubmed/15066364" class="btn btn-primary" target="_blank">View</a> </div>
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</div></div>
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<div class="field field-name-body field-type-text-with-summary field-label-hidden">
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<div class="field-item even" property="content:encoded"><p>BACKGROUND:</p>
<p>To compare the strength of evidence provided by the epidemiological literature on the association between alcohol consumption and the risk of 14 major alcohol-related neoplasms and non-neoplastic diseases, plus injuries.</p>
<p>METHODS:</p>
<p>A search of the epidemiological literature from 1966 to 1998 was performed by several bibliographic databases. Meta-regression models were fitted considering fixed and random effect models and linear and nonlinear effects of alcohol intake. The effects of some characteristics of the studies, including an index of their quality, were considered.</p>
<p>RESULTS:</p>
<p>Of the 561 initially reviewed studies, 156 were selected for meta-analysis because of their a priori defined higher quality, including a total of 116,702 subjects. Strong trends in risk were observed for cancers of the oral cavity, esophagus and larynx, hypertension, liver cirrhosis, chronic pancreatitis, and injuries and violence. Less strong direct relations were observed for cancers of the colon, rectum, liver, and breast. For all these conditions, significant increased risks were also found for ethanol intake of 25 g per day. Threshold values were observed for ischemic and hemorrhagic strokes. For coronary heart disease, a J-shaped relation was observed with a minimum relative risk of 0.80 at 20 g/day, a significant protective effect up to 72 g/day, and a significant increased risk at 89 g/day. No clear relation was observed for gastroduodenal ulcer.</p>
<p>CONCLUSIONS:</p>
<p>This meta-analysis shows no evidence of a threshold effect for both neoplasms and several non-neoplastic diseases. J-shaped relations were observed only for coronary heart disease.</p>
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<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
<div class="field-items">
<div class="field-item even">Corrao, Giovanni, Bagnardi, Vincenzo, Zombon, Antonella, La Cecchia, Carlo</div>
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Wed, 02 Jan 2019 13:40:25 +0000Jeffrey Wilson279 at https://www.rpr.lib.ok.us