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https://www.rpr.lib.ok.us/taxonomy/term/10874/all en https://www.rpr.lib.ok.us/resource/parkinsons-disease <div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Date Added:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2024-09-10T00:00:00-05:00">September 10, 2024</span></div> </div> </div> <div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix"> <div class="field-label">Journal/Publication:&nbsp;</div> <div class="field-items"> <div class="field-item even">New England Journal of Medicine</div> </div> </div> <div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Publication Date:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2024-07-31T00:00:00-05:00">July 31, 2024</span></div> </div> </div> <div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix"> <div class="field-label">Issue:&nbsp;</div> <div class="field-items"> <div class="field-item even">5</div> </div> </div> <div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix"> <div class="field-label">Volume:&nbsp;</div> <div class="field-items"> <div class="field-item even">391</div> </div> </div> <div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix"> <div class="field-label">Pages:&nbsp;</div> <div class="field-items"> <div class="field-item even">442-452</div> </div> </div> <div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix"> <div class="field-label">URL:&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="https://pubmed.ncbi.nlm.nih.gov/39083773/" target="_blank">Parkinson's Disease</a></div> </div> </div> <div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Type:&nbsp;</div> <div class="field-items"> <div class="field-item even">Meta-analyses, Reviews, and Guidelines</div> </div> </div> <div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Format:&nbsp;</div> <div class="field-items"> <div class="field-item even">Article</div> </div> </div> <div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix"> <div class="field-label">DOI (1):&nbsp;</div> <div class="field-items"> <div class="field-item even">10.1056/NEJMra2401857</div> </div> </div> <div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above"> <div class="field-label">Keywords&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/tags/levodopa" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Levodopa</a></div> <div class="field-item odd"><a href="/tags/parkinson-disease" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Parkinson Disease</a></div> </div> </div> <div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix"> <div class="field-label">PMID (1):&nbsp;</div> <div class="field-items"> <div class="field-item even">39083773</div> </div> </div> <div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above"> <div class="field-label">MeSH&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/mesh/antiparkinson-agents-therapeutic-use" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Antiparkinson Agents / therapeutic use</a></div> <div class="field-item odd"><a href="/mesh/levodopa-therapeutic-use" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Levodopa / therapeutic use</a></div> <div class="field-item even"><a href="/mesh/parkinson-disease-diagnosis" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Parkinson Disease* / diagnosis</a></div> <div class="field-item odd"><a href="/mesh/antiparkinson-agents" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Antiparkinson Agents</a></div> <div class="field-item even"><a href="/mesh/levodopa" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Levodopa</a></div> </div> </div> <div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden"> <div class="field-items"> <div class="field-item even"><p>A review of current knowledge about Parkinson's Disease. James W. Mold, MD, MPH</p> </div> </div> </div> <div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden"> <div class="field-items"> <div class="field-item even">Free full text</div> </div> </div> <div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden"> <div class="field-items"> <div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-b49f75a7e021d99517f776f71c0d6951"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <a href="https://pubmed.ncbi.nlm.nih.gov/39083773/" class="btn btn-primary" target="_blank">View</a> </div> </div> </div></div> </div> </div> <div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="content:encoded"><p>The global burden of Parkinson’s disease is projected to increase in future decades as the number and proportion of older adults increases. This review addresses research advances since 1998, when the disorder was last reviewed in the Journal, and includes recently introduced concepts relevant to clinical practice. For two centuries, Parkinson’s disease has been diagnosed clinically on the basis of the characteristic motor syndrome of bradykinesia accompanied by resting tremor, rigidity, and postural reflex impairment, all largely the result of dopaminergic dysfunction in the nigrostriatal system. Advances in our understanding of the disease suggest that a biologic definition may be possible, but many questions remain. In this review, we use the clinical definition of Parkinson’s disease.</p> </div> </div> </div> <div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Author/s:&nbsp;</div> <div class="field-items"> <div class="field-item even">Caroline M. Tanner, Jill L Ostrem</div> </div> </div> Tue, 10 Sep 2024 17:11:07 +0000 Alex Haga 2407 at https://www.rpr.lib.ok.us