Deprecated : Return type of DrupalCacheArray::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 362 Deprecated : Return type of DrupalCacheArray::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 369 Deprecated : Return type of DrupalCacheArray::offsetSet($offset, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 381 Deprecated : Return type of DrupalCacheArray::offsetUnset($offset) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 388
chronic urticaria
en
-
Diagnosis and Treatment of Chronic Spontaneous Urticaria
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2024-10-01T00:00:00-05:00">October 1, 2024</span></div>
</div>
</div>
<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
<div class="field-items">
<div class="field-item even">JAMA</div>
</div>
</div>
<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2024-09-26T00:00:00-05:00">September 26, 2024</span></div>
</div>
</div>
<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
<div class="field-items">
<div class="field-item even"><a href="https://edhub.ama-assn.org/jn-learning/audio-player/18914701?utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=092624&adv=000003220113" target="_blank">Diagnosis and Treatment of Chronic Spontaneous Urticaria</a></div>
</div>
</div>
<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
<div class="field-items">
<div class="field-item even">Meta-analyses, Reviews, and Guidelines</div>
</div>
</div>
<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
<div class="field-items">
<div class="field-item even">Web Page</div>
</div>
</div>
<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
<div class="field-items">
<div class="field-item even"><a href="/tags/chronic-spontaneous-urticaria" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Chronic Spontaneous Urticaria</a></div>
<div class="field-item odd"><a href="/tags/chronic-urticaria" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">chronic urticaria</a></div>
<div class="field-item even"><a href="/tags/urticaria" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">urticaria</a></div>
</div>
</div>
<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/chronic-urticaria" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Chronic Urticaria</a></div>
<div class="field-item odd"><a href="/mesh/comorbidity" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">comorbidity</a></div>
<div class="field-item even"><a href="/mesh/urticaria" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Urticaria</a></div>
</div>
</div>
<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
<div class="field-items">
<div class="field-item even"><p>An 18-minute audiotape on the subject of chronic urticaria. James W. Mold, MD, MPH</p>
</div>
</div>
</div>
<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
<div class="field-items">
<div class="field-item even">Free full text</div>
</div>
</div>
<div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden">
<div class="field-items">
<div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-e6e9eec593d72ddd652d6a7ea29a4c5e">
<div class="view-content">
<div class="views-row views-row-1 views-row-odd views-row-first views-row-last">
<a href="https://edhub.ama-assn.org/jn-learning/audio-player/18914701?utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=092624&adv=000003220113" class="btn btn-primary" target="_blank">View</a> </div>
</div>
</div></div>
</div>
</div>
<div class="field field-name-body field-type-text-with-summary field-label-hidden">
<div class="field-items">
<div class="field-item even" property="content:encoded"><p>Chronic spontaneous urticaria affects approximately 1% of the general population worldwide, impairs patients’ quality of life, and is associated with multiple comorbidities. Pavel Kolkhir, MD, discusses the current evidence on the epidemiology, pathophysiology, diagnosis, and treatment of chronic spontaneous urticaria with JAMA Senior Editor Karen E. Lasser, MD, MPH.</p>
</div>
</div>
</div>
<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
<div class="field-items">
<div class="field-item even">Pavel Kolkhir, Karen E. Lasser</div>
</div>
</div>
Tue, 01 Oct 2024 17:10:47 +0000
Alex Haga
2431 at https://www.rpr.lib.ok.us
-
Chronic urticaria: unmet needs, emerging drugs, and new perspectives on personalised treatment
<div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Date Added: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2024-08-04T00:00:00-05:00">August 4, 2024</span></div>
</div>
</div>
<div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix">
<div class="field-label">Journal/Publication: </div>
<div class="field-items">
<div class="field-item even">Lancet</div>
</div>
</div>
<div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix">
<div class="field-label">Publication Date: </div>
<div class="field-items">
<div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2024-07-27T00:00:00-05:00">July 27, 2024</span></div>
</div>
</div>
<div class="field field-name-field-artifact-issue field-type-text field-label-inline clearfix">
<div class="field-label">Issue: </div>
<div class="field-items">
<div class="field-item even">10450</div>
</div>
</div>
<div class="field field-name-field-artifact-volume field-type-text field-label-inline clearfix">
<div class="field-label">Volume: </div>
<div class="field-items">
<div class="field-item even">404</div>
</div>
</div>
<div class="field field-name-field-artifact-pages field-type-text field-label-inline clearfix">
<div class="field-label">Pages: </div>
<div class="field-items">
<div class="field-item even">393-404</div>
</div>
</div>
<div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix">
<div class="field-label">URL: </div>
<div class="field-items">
<div class="field-item even"><a href="https://pubmed.ncbi.nlm.nih.gov/39004090/" target="_blank">Chronic urticaria: unmet needs, emerging drugs, and new perspectives on personalised treatment</a></div>
</div>
</div>
<div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Type: </div>
<div class="field-items">
<div class="field-item even">Meta-analyses, Reviews, and Guidelines</div>
</div>
</div>
<div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Format: </div>
<div class="field-items">
<div class="field-item even">Article</div>
</div>
</div>
<div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix">
<div class="field-label">DOI (1): </div>
<div class="field-items">
<div class="field-item even">10.1016/S0140-6736(24)00852-3</div>
</div>
</div>
<div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above">
<div class="field-label">Keywords </div>
<div class="field-items">
<div class="field-item even"><a href="/tags/urticaria" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">urticaria</a></div>
<div class="field-item odd"><a href="/tags/chronic-urticaria" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">chronic urticaria</a></div>
<div class="field-item even"><a href="/tags/omalizumab" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">omalizumab</a></div>
</div>
</div>
<div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix">
<div class="field-label">PMID (1): </div>
<div class="field-items">
<div class="field-item even">39004090</div>
</div>
</div>
<div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above">
<div class="field-label">MeSH </div>
<div class="field-items">
<div class="field-item even"><a href="/mesh/chronic-urticaria-drug-therapy" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Chronic Urticaria* / drug therapy</a></div>
<div class="field-item odd"><a href="/mesh/agammaglobulinaemia-tyrosine-kinase-antagonists-inhibitors" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Agammaglobulinaemia Tyrosine Kinase / antagonists & inhibitors</a></div>
<div class="field-item even"><a href="/mesh/cyclosporine-therapeutic-use" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Cyclosporine / therapeutic use</a></div>
<div class="field-item odd"><a href="/mesh/mast-cells-drug-effects" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Mast Cells / drug effects</a></div>
<div class="field-item even"><a href="/mesh/omalizumab-therapeutic-use" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Omalizumab* / therapeutic use</a></div>
</div>
</div>
<div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden">
<div class="field-items">
<div class="field-item even"><p>A review of what we know and don't know about chronic urticaria and its treatment. James W. Mold, MD, MPH</p>
</div>
</div>
</div>
<div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden">
<div class="field-items">
<div class="field-item even">Free full text</div>
</div>
</div>
<div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden">
<div class="field-items">
<div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-44e9043bc45c9865659adfb01569fca9">
<div class="view-content">
<div class="views-row views-row-1 views-row-odd views-row-first views-row-last">
<a href="https://pubmed.ncbi.nlm.nih.gov/39004090/" class="btn btn-primary" target="_blank">View</a> </div>
</div>
</div></div>
</div>
</div>
<div class="field field-name-body field-type-text-with-summary field-label-hidden">
<div class="field-items">
<div class="field-item even" property="content:encoded"><p>Chronic urticaria is a common and debilitating mast cell-driven skin disease presenting with itchy wheals, angio-oedema, or both. Chronic urticaria is classified as spontaneous (without definite triggers) and inducible (with definite and subtype-specific triggers; eg, cold or pressure). Current management guidelines recommend step-up administration of second-generation H1-antihistamines to four-fold the approved dose, followed by omalizumab and ciclosporin. However, in many patients, chronic urticaria does not respond to this linear approach due to heterogeneous underlying mechanisms. A personalised endotype-based approach is emerging based on the identification of autoantibodies and other drivers of urticaria pathogenesis. Over the past decade, clinical trials have presented promising options for targeted treatment of chronic urticaria with the potential for disease modification, including Bruton's tyrosine kinase inhibitors, anti-cytokine therapies, and mast cell depletion. This Therapeutics article focuses on the evidence for these novel drugs and their role in addressing an unmet need for personalised management of patients with chronic urticaria.</p>
</div>
</div>
</div>
<div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix">
<div class="field-label">Author/s: </div>
<div class="field-items">
<div class="field-item even">Torsten Zuberbier, Luis Felipe Ensina, Ana Giménez-Arnau, Clive Grattan</div>
</div>
</div>
Sun, 04 Aug 2024 18:10:28 +0000
Alex Haga
2367 at https://www.rpr.lib.ok.us