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Methicillin-Resistant Staphylococcus aureus https://www.rpr.lib.ok.us/taxonomy/term/10579/all en Opioid-Induced Adrenal Insufficiency https://www.rpr.lib.ok.us/resource/opioid-induced-adrenal-insufficiency <div class="field field-name-field-artifact-uploaded-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Date Added:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2024-05-22T00:00:00-05:00">May 22, 2024</span></div> </div> </div> <div class="field field-name-field-artifact-journal field-type-text field-label-inline clearfix"> <div class="field-label">Journal/Publication:&nbsp;</div> <div class="field-items"> <div class="field-item even">JAMA International Medicine</div> </div> </div> <div class="field field-name-field-artifact-publisher field-type-text field-label-inline clearfix"> <div class="field-label">Publisher:&nbsp;</div> <div class="field-items"> <div class="field-item even">American Medical Association</div> </div> </div> <div class="field field-name-field-artifact-published-date field-type-datetime field-label-inline clearfix"> <div class="field-label">Publication Date:&nbsp;</div> <div class="field-items"> <div class="field-item even"><span class="date-display-single" property="dc:date" datatype="xsd:dateTime" content="2024-05-13T00:00:00-05:00">May 13, 2024</span></div> </div> </div> <div class="field field-name-field-artifact-url field-type-link-field field-label-inline clearfix"> <div class="field-label">URL:&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="https://pubmed.ncbi.nlm.nih.gov/38739374/" target="_blank">Opioid-Induced Adrenal Insufficiency</a></div> </div> </div> <div class="field field-name-field-artifact-type field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Type:&nbsp;</div> <div class="field-items"> <div class="field-item even">Meta-analyses, Reviews, and Guidelines</div> </div> </div> <div class="field field-name-field-artifact-format field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Format:&nbsp;</div> <div class="field-items"> <div class="field-item even">Article</div> </div> </div> <div class="field field-name-field-artifact-doi-1 field-type-text field-label-inline clearfix"> <div class="field-label">DOI (1):&nbsp;</div> <div class="field-items"> <div class="field-item even">10.1001/jamainternmed.2024.0687</div> </div> </div> <div class="field field-name-field-artifact-keywords field-type-taxonomy-term-reference field-label-above"> <div class="field-label">Keywords&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/tags/opioid-related-disorders" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Opioid-Related Disorders</a></div> <div class="field-item odd"><a href="/tags/opioid-use" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Opioid Use</a></div> <div class="field-item even"><a href="/tags/hyponatremia" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Hyponatremia</a></div> <div class="field-item odd"><a href="/tags/methicillin-resistant-staphylococcus-aureus" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Methicillin-Resistant Staphylococcus aureus</a></div> <div class="field-item even"><a href="/tags/methadone" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">methadone</a></div> <div class="field-item odd"><a href="/tags/opioids" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">opioids</a></div> <div class="field-item even"><a href="/tags/endocrinology" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Endocrinology</a></div> <div class="field-item odd"><a href="/tags/diabetes-and-endocrinology" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Diabetes and Endocrinology</a></div> </div> </div> <div class="field field-name-field-artifact-pmid-1 field-type-text field-label-inline clearfix"> <div class="field-label">PMID (1):&nbsp;</div> <div class="field-items"> <div class="field-item even">38739374</div> </div> </div> <div class="field field-name-field-artifact-mesh field-type-taxonomy-term-reference field-label-above"> <div class="field-label">MeSH&nbsp;</div> <div class="field-items"> <div class="field-item even"><a href="/mesh/opioid-related-disorders" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">opioid-related disorders</a></div> <div class="field-item odd"><a href="/mesh/hyponatremia" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Hyponatremia</a></div> <div class="field-item even"><a href="/mesh/methicillin-resistant-staphylococcus-aureus" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Methicillin-Resistant Staphylococcus aureus</a></div> <div class="field-item odd"><a href="/mesh/methadone" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">methadone</a></div> </div> </div> <div class="field field-name-field-artifact-editor-note field-type-text-long field-label-hidden"> <div class="field-items"> <div class="field-item even"><p>Chronic use of opioids can result in suppression of the hypothalamic, pituitary, adrenal axis causing adrenal insufficiency in up to 15% of patients. James W. Mold, MD, MPH</p> </div> </div> </div> <div class="field field-name-field-artifact-text-availability field-type-list-text field-label-hidden"> <div class="field-items"> <div class="field-item even">Commercial full text (fees may apply)</div> </div> </div> <div class="field field-name-field-artifact-document-content field-type-entityreference field-label-hidden"> <div class="field-items"> <div class="field-item even"><div class="view view-artifact-docs view-id-artifact_docs view-display-id-block view-dom-id-86d2286be803c471e00954611c42e203"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first views-row-last"> <a href="https://pubmed.ncbi.nlm.nih.gov/38739374/" class="btn btn-primary" target="_blank">View</a> </div> </div> </div></div> </div> </div> <div class="field field-name-body field-type-text-with-summary field-label-hidden"> <div class="field-items"> <div class="field-item even" property="content:encoded"><p>A woman in her 40s with opioid use disorder receiving methadone (70 mg daily) was admitted for extended antibiotic treatment for methicillin-resistant Staphylococcus aureus bacteremia. She had been taking methadone at varying doses (ranging from 15 to 70 mg daily) for 15 years.</p> <p>Following the resolution of bacteremia, she experienced unexplained persistent hyponatremia (129 mEq/L) and dizziness, with her urine sodium levels exceeding 40 mEq/L. A high dose, 250-μg cosyntropin stimulation test was performed, which revealed her cortisol levels were 6.6, 17.2, and 19.2 μg/mL (to convert to nmol/L, multiply by 27.6) at baseline, 30 minutes, and 60 minutes, respectively. A serum adrenocorticotropic hormone (ACTH) level was not measured.</p> </div> </div> </div> <div class="field field-name-field-resource-author field-type-taxonomy-term-reference field-label-inline clearfix"> <div class="field-label">Author/s:&nbsp;</div> <div class="field-items"> <div class="field-item even">Douglas Rice, Hirofumi Yoshida</div> </div> </div> Wed, 22 May 2024 23:12:22 +0000 Erin Blanchette 2315 at https://www.rpr.lib.ok.us